Detection and prevalence of depression among adult type 2 diabetes mellitus patients attending non-communicable diseases clinics in Lilongwe, Malawi.

Depression Malawi Type 2 diabetes mellitus

Journal

International journal of mental health systems
ISSN: 1752-4458
Titre abrégé: Int J Ment Health Syst
Pays: England
ID NLM: 101294224

Informations de publication

Date de publication:
04 Nov 2020
Historique:
received: 01 07 2020
accepted: 29 10 2020
entrez: 9 12 2020
pubmed: 10 12 2020
medline: 10 12 2020
Statut: epublish

Résumé

Depression is associated with chronic physical illnesses and negatively affects health outcomes. However, it often goes undiagnosed and untreated. We investigated the prevalence of depression among adult type 2 diabetes mellitus (T2DM) patients attending non-communicable diseases (NCD) clinics in Lilongwe, Malawi, and estimated the level of routine detection by NCD clinicians. This study set out to determine the prevalence of major depression and its detection among adult type 2 diabetes mellitus (T2DM) patients attending NCD clinics in Lilongwe, Malawi. In a cross-sectional study design, 323 T2DM patients aged ≥ 18 years were screened for depression with the Patient Health Questionnare-9 (PHQ-9) followed by diagnostic assessment with the Structured Clinical Interview for DSM-IV (SCID). We analysed the association between presence of major depression and sociodemographic factors using logistic regression. Three quarters of the participants (76%) were females. The participants' ages ranged from 21-79 years. Of the 323 participants, 58 (18%) met criteria for DSM-IV major depression. None of the cases of major depression had been identified by the NCD clinicians. Major depression was found not to be significantly associated with any of the sociodemographic factors. We found that depression is common among NCD clinic attendees with T2DM in Malawi, and poorly detected by NCD clinicians. Given the high prevalence and challenges in clinical identification, integration of depression screening with a standardized validated tool should be a high priority so as to link patients to appropriate services.

Sections du résumé

BACKGROUND BACKGROUND
Depression is associated with chronic physical illnesses and negatively affects health outcomes. However, it often goes undiagnosed and untreated. We investigated the prevalence of depression among adult type 2 diabetes mellitus (T2DM) patients attending non-communicable diseases (NCD) clinics in Lilongwe, Malawi, and estimated the level of routine detection by NCD clinicians. This study set out to determine the prevalence of major depression and its detection among adult type 2 diabetes mellitus (T2DM) patients attending NCD clinics in Lilongwe, Malawi.
METHODS METHODS
In a cross-sectional study design, 323 T2DM patients aged ≥ 18 years were screened for depression with the Patient Health Questionnare-9 (PHQ-9) followed by diagnostic assessment with the Structured Clinical Interview for DSM-IV (SCID). We analysed the association between presence of major depression and sociodemographic factors using logistic regression.
RESULTS RESULTS
Three quarters of the participants (76%) were females. The participants' ages ranged from 21-79 years. Of the 323 participants, 58 (18%) met criteria for DSM-IV major depression. None of the cases of major depression had been identified by the NCD clinicians. Major depression was found not to be significantly associated with any of the sociodemographic factors.
CONCLUSIONS CONCLUSIONS
We found that depression is common among NCD clinic attendees with T2DM in Malawi, and poorly detected by NCD clinicians. Given the high prevalence and challenges in clinical identification, integration of depression screening with a standardized validated tool should be a high priority so as to link patients to appropriate services.

Identifiants

pubmed: 33292422
doi: 10.1186/s13033-020-00413-3
pii: 10.1186/s13033-020-00413-3
pmc: PMC7640665
doi:

Types de publication

Journal Article

Langues

eng

Pagination

79

Subventions

Organisme : Wellcome Trust
ID : DEL-15-01
Pays : United Kingdom

Références

Diabetes Res Clin Pract. 2009 Feb;83(2):268-79
pubmed: 19111364
J Epidemiol. 2008;18(5):204-8
pubmed: 18753734
PLoS Med. 2013;10(5):e1001435
pubmed: 23667343
PLoS One. 2016 Jun 29;11(6):e0155966
pubmed: 27355447
Br J Gen Pract. 2010 Jun;60(575):e239-45
pubmed: 20529487
BMC Psychiatry. 2013 Oct 14;13:260
pubmed: 24125027
Gen Hosp Psychiatry. 2010 Jan-Feb;32(1):33-41
pubmed: 20114126
Diabetes Metab Syndr Obes. 2018 Jul 10;11:333-343
pubmed: 30022843
Indian J Endocrinol Metab. 2012 Sep;16(5):764-8
pubmed: 23087861
PLoS Med. 2009 Oct;6(10):e1000160
pubmed: 19806180
Lancet. 2007 Oct 6;370(9594):1241-52
pubmed: 17804059
J Affect Disord. 2012 Oct;142 Suppl:S8-21
pubmed: 23062861
J Diabetes Complications. 2005 Mar-Apr;19(2):113-22
pubmed: 15745842
Curr Med Res Opin. 2009 Jul;25(7):1763-73
pubmed: 19505204
Depress Res Treat. 2018 May 23;2018:6135460
pubmed: 29951313
J Neurosci Rural Pract. 2014 Jul;5(3):250-3
pubmed: 25002763
PLoS One. 2012;7(5):e36887
pubmed: 22629339
PLoS One. 2009 Sep 28;4(9):e7185
pubmed: 19784380
Diabetes Care. 2003 Oct;26(10):2822-8
pubmed: 14514586
Indian J Psychol Med. 2012 Jan;34(1):30-3
pubmed: 22661804
PLoS One. 2016 Jun 16;11(6):e0156939
pubmed: 27310297
Diabetes Care. 2004 Apr;27(4):914-20
pubmed: 15047648
BMC Public Health. 2014 Feb 13;14:163
pubmed: 24524353
Malawi Med J. 2008 Sep;20(3):74-7
pubmed: 19537402
Diabetes Res Clin Pract. 2014 Feb;103(2):276-85
pubmed: 24485858
Psychosom Med. 1997 May-Jun;59(3):241-50
pubmed: 9178335
PLoS Med. 2013;10(5):e1001443
pubmed: 23690753
BMJ. 2011 May 13;342:d2600
pubmed: 21571914
Diabet Med. 2018 Jun;35(6):760-769
pubmed: 29478265
Diabetes Care. 2010 Feb;33(2):264-9
pubmed: 19933989
BMJ Open. 2018 Oct 15;8(10):e021601
pubmed: 30327400
Diabetes Care. 2001 Jun;24(6):1069-78
pubmed: 11375373
J Affect Disord. 2004 Jul;81(1):61-6
pubmed: 15183601
Malawi Med J. 2014 Jun;26(2):34-7
pubmed: 25157314
Lancet. 2007 Sep 8;370(9590):851-8
pubmed: 17826170
BMC Psychiatry. 2018 Nov 6;18(1):357
pubmed: 30400843
Indian J Psychol Med. 2017 Jan-Feb;39(1):52-58
pubmed: 28250559
Health Aff (Millwood). 2015 Sep;34(9):1498-505
pubmed: 26355051
Med Care. 2004 Dec;42(12):1194-201
pubmed: 15550799
PLoS One. 2011;6(5):e20316
pubmed: 21629735
Psychol Med. 2014 Feb;44(3):657-66
pubmed: 23721658
Psychosom Med. 2001 Jul-Aug;63(4):619-30
pubmed: 11485116
Diabetes Care. 2000 May;23(5):618-23
pubmed: 10834419
Diabetes Care. 2004 Sep;27(9):2154-60
pubmed: 15333477
Hum Resour Health. 2018 Jul 11;16(1):31
pubmed: 29996852
Mymensingh Med J. 2012 Jul;21(3):490-6
pubmed: 22828549
BMC Endocr Disord. 2014 May 12;14:41
pubmed: 24884894
Int J Gen Med. 2018 Jun 28;11:255-264
pubmed: 29988742
Diabet Med. 2000 Mar;17(3):198-202
pubmed: 10784223
World Psychiatry. 2010 Oct;9(3):169-76
pubmed: 20975864
J Gen Intern Med. 2001 Sep;16(9):606-13
pubmed: 11556941
Indian J Med Res. 2010 Aug;132:195-200
pubmed: 20716820
BMC Psychiatry. 2019 Feb 27;19(1):81
pubmed: 30813922
Croat Med J. 2009 Feb;50(1):77-8
pubmed: 19260148
Diabetes Care. 2009 Dec;32(12):2156-60
pubmed: 19729522
Diabetol Metab Syndr. 2010 Dec 20;2:72
pubmed: 21171976
Psychiatry J. 2019 Jan 15;2019:2083196
pubmed: 30775378

Auteurs

Michael Udedi (M)

Department of Mental Health, College of Medicine, University of Malawi, Chichiri, P/Bag 360, Blantyre 3, Malawi. mphatsoudedi@yahoo.co.uk.
Department of Clinical Services, Ministry of Health, P. O. Box 30377, Capital City, Lilongwe 3, Malawi. mphatsoudedi@yahoo.co.uk.
Department of Public Health, College of Medicine, University of Malawi, Chichiri, P/Bag 360, Blantyre 3, Malawi. mphatsoudedi@yahoo.co.uk.

Brian W Pence (BW)

Epidemiology Department, University of North Carolina At Chapel Hill Gillings School of Global Public Health, 135 Dauer Dr, Chapel Hill, NC, 27599, USA.

Robert C Stewart (RC)

Department of Mental Health, College of Medicine, University of Malawi, Chichiri, P/Bag 360, Blantyre 3, Malawi.
Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Morningside Park, Edinburgh, EH10 5HF, UK.
Malawi Epidemiology and Intervention Research Unit (MEIRU), Box 148, Lilongwe 3, Malawi.

Adamson S Muula (AS)

Department of Public Health, College of Medicine, University of Malawi, Chichiri, P/Bag 360, Blantyre 3, Malawi.
Africa Center of Excellence in Public Health and Herbal Medicine, College of Medicine, University of Malawi, Chichiri, P/Bag 360, Blantyre 3, Malawi.

Classifications MeSH