The outcome at follow-up after inpatient eating disorder treatment: a naturalistic study.
Adults
Eating disorders
Follow-up
Inpatient treatment
Outcome predictors
Remission
Treatment outcome
Journal
Journal of eating disorders
ISSN: 2050-2974
Titre abrégé: J Eat Disord
Pays: England
ID NLM: 101610672
Informations de publication
Date de publication:
02 Dec 2020
02 Dec 2020
Historique:
received:
29
06
2020
accepted:
03
11
2020
entrez:
9
12
2020
pubmed:
10
12
2020
medline:
10
12
2020
Statut:
epublish
Résumé
Patients with eating disorders may experience a severe and enduring course of illness. Treatment outcome for patients provided with inpatient treatment is reported as poor. Research to date has not provided consistent results for predictors of treatment outcome. The aims of the study were to investigate rates of remission at follow-up after inpatient treatment, symptom change from admission to follow-up, and predictors of treatment outcome. The follow-up sample consisted of 150 female adult former patients (69.4% of all eligible female patients) with eating disorders. Mean age at admission was 21.7 (SD = 4.9) years. Diagnostic distribution: 66% (n = 99) anorexia nervosa, 21.3% (n = 32) bulimia nervosa and 12.7% (n = 19) other specified feeding or eating disorder, including binge eating. Data were collected at admission, discharge and follow-up (mean 2.7 (SD = 1.9) years). Definition of remission was based on the EDE-Q Global score, body mass index and binge/purge behavior. Paired T-tests were performed to investigate change over time. Univariate and multivariate logistic regressions were estimated to investigate predictors of remission. At follow-up, 35.2% of the participants were classified as in remission. Significant symptom reduction (in all patients) (p < 0.001) and significant increase in body mass index (BMI) (in underweight participants at admission) (p < 0.001) was found. Increased BMI (p < 0.05), the level of core eating disorder symptoms at admission (p < 0.01) and reduced core eating disorder symptoms (p < 0.01) during inpatient treatment were found significant predictors of outcome in the multivariate model. All participants had an eating disorder requiring inpatient treatment. Approximately one-third of all participants could be classified as in remission at follow-up. However, most participants experienced significant symptom improvement during inpatient treatment and the improvements were sustained at follow-up. Increased probability of remission at follow-up was indicated by lower core ED symptoms at admission for all patients, raised BMI during admission for patients with AN, and reduced core ED symptoms during inpatient treatment for all patients. This finding contributes important information and highlights the importance of targeting these core symptoms in transdiagnostic treatment programs.
Sections du résumé
BACKGROUND
BACKGROUND
Patients with eating disorders may experience a severe and enduring course of illness. Treatment outcome for patients provided with inpatient treatment is reported as poor. Research to date has not provided consistent results for predictors of treatment outcome. The aims of the study were to investigate rates of remission at follow-up after inpatient treatment, symptom change from admission to follow-up, and predictors of treatment outcome.
METHODS
METHODS
The follow-up sample consisted of 150 female adult former patients (69.4% of all eligible female patients) with eating disorders. Mean age at admission was 21.7 (SD = 4.9) years. Diagnostic distribution: 66% (n = 99) anorexia nervosa, 21.3% (n = 32) bulimia nervosa and 12.7% (n = 19) other specified feeding or eating disorder, including binge eating. Data were collected at admission, discharge and follow-up (mean 2.7 (SD = 1.9) years). Definition of remission was based on the EDE-Q Global score, body mass index and binge/purge behavior. Paired T-tests were performed to investigate change over time. Univariate and multivariate logistic regressions were estimated to investigate predictors of remission.
RESULTS
RESULTS
At follow-up, 35.2% of the participants were classified as in remission. Significant symptom reduction (in all patients) (p < 0.001) and significant increase in body mass index (BMI) (in underweight participants at admission) (p < 0.001) was found. Increased BMI (p < 0.05), the level of core eating disorder symptoms at admission (p < 0.01) and reduced core eating disorder symptoms (p < 0.01) during inpatient treatment were found significant predictors of outcome in the multivariate model.
CONCLUSIONS
CONCLUSIONS
All participants had an eating disorder requiring inpatient treatment. Approximately one-third of all participants could be classified as in remission at follow-up. However, most participants experienced significant symptom improvement during inpatient treatment and the improvements were sustained at follow-up. Increased probability of remission at follow-up was indicated by lower core ED symptoms at admission for all patients, raised BMI during admission for patients with AN, and reduced core ED symptoms during inpatient treatment for all patients. This finding contributes important information and highlights the importance of targeting these core symptoms in transdiagnostic treatment programs.
Identifiants
pubmed: 33292634
doi: 10.1186/s40337-020-00349-6
pii: 10.1186/s40337-020-00349-6
pmc: PMC7709321
doi:
Types de publication
Journal Article
Langues
eng
Pagination
67Références
Psychother Psychosom. 2013;82(6):390-8
pubmed: 24060628
Eur Eat Disord Rev. 2009 Sep-Oct;17(5):366-70
pubmed: 19618382
Eur Eat Disord Rev. 2015 Sep;23(5):408-12
pubmed: 26094887
Arch Pediatr Adolesc Med. 1997 Jan;151(1):16-21
pubmed: 9006523
Eat Disord. 2011 Mar-Apr;19(2):132-44
pubmed: 21360364
Int J Eat Disord. 2006 Mar;39(2):87-100
pubmed: 16231345
Int J Eat Disord. 2019 Jul;52(7):834-845
pubmed: 31002430
Int J Eat Disord. 2007 May;40(4):293-309
pubmed: 17370291
Psychother Res. 2018 Mar;28(2):297-312
pubmed: 27456048
Int J Eat Disord. 2017 Sep;50(9):1018-1030
pubmed: 28644530
Eat Weight Disord. 2010 Mar-Jun;15(1-2):e74-80
pubmed: 20571324
Child Adolesc Psychiatr Clin N Am. 2009 Jan;18(1):225-42
pubmed: 19014869
BMC Psychiatry. 2014 Sep 06;14:258
pubmed: 25193513
BMC Health Serv Res. 2018 Jan 15;18(1):22
pubmed: 29334934
Int J Eat Disord. 1999 Dec;26(4):359-85
pubmed: 10550777
Front Psychol. 2018 Dec 11;9:2456
pubmed: 30618916
Psychol Med. 2009 Jun;39(6):1037-45
pubmed: 18845008
J Psychosom Res. 2014 Jan;76(1):12-8
pubmed: 24360135
Am J Psychiatry. 2006 Jul;163(7 Suppl):4-54
pubmed: 16925191
Eur Eat Disord Rev. 2020 May;28(3):246-259
pubmed: 32196843
Behav Res Ther. 2010 Mar;48(3):194-202
pubmed: 19945094
Eur Eat Disord Rev. 2009 Nov;17(6):462-7
pubmed: 19504471
Clin Psychol Rev. 2012 Jun;32(4):292-300
pubmed: 22459790
Front Psychol. 2020 Jan 17;10:2985
pubmed: 32010027
Int J Eat Disord. 2010 Apr;43(3):195-204
pubmed: 20186717
Int J Eat Disord. 2006 Apr;39(3):175-83
pubmed: 16485268
Psychiatry Res. 2014 Aug 15;218(1-2):195-200
pubmed: 24794153
Int J Eat Disord. 2016 Apr;49(4):432-3
pubmed: 27084797
J Eat Disord. 2018 Sep 25;6:34
pubmed: 30258631
J Eat Disord. 2017 Jun 14;5:20
pubmed: 28630708
Int J Eat Disord. 1997 Dec;22(4):361-84
pubmed: 9356885
Nord J Psychiatry. 2006;60(1):44-50
pubmed: 16500799
J Pers Assess. 1990 Winter;55(3-4):521-36
pubmed: 2280321
Eur Eat Disord Rev. 2011 Jan-Feb;19(1):2-11
pubmed: 20597067
Eat Disord. 2012;20(4):261-75
pubmed: 22703568
Int J Eat Disord. 2001 Jul;30(1):69-74
pubmed: 11439410
Nord J Psychiatry. 2010 Dec;64(6):428-32
pubmed: 20429744