Nucleic Acids Analysis.
DNA nanotechnology
aptamer
biosensing
nucleic acids analysis
signal amplification
Journal
Science China. Chemistry
ISSN: 1674-7291
Titre abrégé: Sci China Chem
Pays: China
ID NLM: 101532738
Informations de publication
Date de publication:
2021
2021
Historique:
received:
09
07
2020
accepted:
04
09
2020
pubmed:
10
12
2020
medline:
10
12
2020
entrez:
9
12
2020
Statut:
ppublish
Résumé
Nucleic acids are natural biopolymers of nucleotides that store, encode, transmit and express genetic information, which play central roles in diverse cellular events and diseases in living things. The analysis of nucleic acids and nucleic acids-based analysis have been widely applied in biological studies, clinical diagnosis, environmental analysis, food safety and forensic analysis. During the past decades, the field of nucleic acids analysis has been rapidly advancing with many technological breakthroughs. In this review, we focus on the methods developed for analyzing nucleic acids, nucleic acids-based analysis, device for nucleic acids analysis, and applications of nucleic acids analysis. The representative strategies for the development of new nucleic acids analysis in this field are summarized, and key advantages and possible limitations are discussed. Finally, a brief perspective on existing challenges and further research development is provided.
Identifiants
pubmed: 33293939
doi: 10.1007/s11426-020-9864-7
pii: 9864
pmc: PMC7716629
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
171-203Informations de copyright
© Science China Press and Springer-Verlag GmbH Germany, part of Springer Nature 2020.
Références
Biosens Bioelectron. 2016 Jul 15;81:487-494
pubmed: 27016627
Biosens Bioelectron. 2015 Dec 15;74:587-93
pubmed: 26190470
J Clin Microbiol. 2010 Jan;48(1):229-37
pubmed: 19864480
Eur J Pharm Sci. 2003 Feb;18(2):129-32
pubmed: 12594005
Anal Chem. 2017 May 2;89(9):4776-4780
pubmed: 28394117
Anal Chim Acta. 2017 Feb 1;952:32-40
pubmed: 28010840
ACS Appl Mater Interfaces. 2015 Jun 17;7(23):12708-12
pubmed: 26018359
Analyst. 2019 Nov 18;144(23):7032-7040
pubmed: 31651914
Angew Chem Int Ed Engl. 2016 Feb 18;55(8):2709-13
pubmed: 26748431
Chem Soc Rev. 2008 May;37(5):1052-60
pubmed: 18443689
Biosens Bioelectron. 2019 Mar 15;129:124-131
pubmed: 30690176
Nat Biotechnol. 1998 Apr;16(4):359-63
pubmed: 9555727
ACS Sens. 2019 Oct 25;4(10):2605-2614
pubmed: 31514496
Nucleic Acids Res. 2000 Jun 15;28(12):E63
pubmed: 10871386
Mass Spectrom Rev. 2001 Sep-Oct;20(5):310-43
pubmed: 11948655
Nature. 2009 Nov 26;462(7272):461-4
pubmed: 19940916
J Invest Dermatol. 2013 Mar;133(3):1-4
pubmed: 23399825
Nat Commun. 2017 Mar 06;8:14378
pubmed: 28262725
Nat Nanotechnol. 2010 Dec;5(12):833-42
pubmed: 21102465
Chem Sci. 2018 Apr 2;9(17):4160-4167
pubmed: 29780546
Int J Mol Sci. 2018 Jul 20;19(7):
pubmed: 30037005
Anal Chem. 2020 Feb 4;92(3):2739-2747
pubmed: 31977184
Chem Soc Rev. 2016 Mar 7;45(5):1410-31
pubmed: 26758955
Ann Rev Mar Sci. 2011;3:347-71
pubmed: 21329209
Anal Chem. 2016 Jul 19;88(14):7289-94
pubmed: 27306491
Anal Chem. 2018 Aug 7;90(15):8919-8926
pubmed: 29987923
Methods Mol Biol. 2014;1096:101-10
pubmed: 24515363
Nat Chem. 2020 Jan;12(1):26-35
pubmed: 31767992
Angew Chem Int Ed Engl. 2010 Apr 1;49(15):2720-3
pubmed: 20232423
Sci Rep. 2017 May 2;7(1):1347
pubmed: 28465576
Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15687-92
pubmed: 12429852
Electrophoresis. 2012 Dec;33(23):3397-417
pubmed: 23208921
Chem Sci. 2019 Jan 22;10(10):3103-3109
pubmed: 30996893
Biosens Bioelectron. 2010 Dec 15;26(4):1386-91
pubmed: 20692149
Biomacromolecules. 2008 Mar;9(3):935-41
pubmed: 18293902
Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5315-20
pubmed: 23509279
Biosens Bioelectron. 2014 May 15;55:39-43
pubmed: 24361420
Biosens Bioelectron. 2011 Dec 15;30(1):73-7
pubmed: 21940158
J Cancer Res Clin Oncol. 2014 Jan;140(1):145-150
pubmed: 24281335
Forensic Sci Int Genet. 2018 Nov;37:162-171
pubmed: 30176438
Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3960-4
pubmed: 12651960
Angew Chem Int Ed Engl. 2020 Aug 3;59(32):13267-13272
pubmed: 32367682
Clin Chem. 2015 Jan;61(1):25-31
pubmed: 25477535
Science. 2015 Apr 24;348(6233):aaa6090
pubmed: 25858977
Angew Chem Int Ed Engl. 2016 Feb 12;55(7):2431-4
pubmed: 26676768
Genome Biol. 2016 Jun 17;17(1):130
pubmed: 27315811
Nano Lett. 2018 Jun 13;18(6):3557-3564
pubmed: 29756442
Nat Rev Mol Cell Biol. 2017 Aug;18(8):507-516
pubmed: 28537574
Anal Chem. 2018 Sep 4;90(17):10434-10441
pubmed: 30073833
Sci Rep. 2016 Oct 14;6:35451
pubmed: 27739510
Anal Bioanal Chem. 2013 Jan;405(2-3):1025-34
pubmed: 23099529
Nature. 2017 Dec 6;552(7683):72-77
pubmed: 29219968
Cold Spring Harb Symp Quant Biol. 1986;51 Pt 1:263-73
pubmed: 3472723
Chem Commun (Camb). 2012 Nov 11;48(87):10733-5
pubmed: 23011391
Nucleic Acids Res. 2002 Dec 15;30(24):e137
pubmed: 12490728
Nat Biotechnol. 1996 Mar;14(3):303-8
pubmed: 9630890
Nano Lett. 2014 Jul 9;14(7):3908-13
pubmed: 24857406
Biosens Bioelectron. 2019 Jan 1;123:160-166
pubmed: 30139622
Forensic Sci Int. 2005 Aug 11;152(1):1-12
pubmed: 15939171
Analyst. 2012 Sep 7;137(17):3940-5
pubmed: 22679625
Genome Biol. 2018 Jul 13;19(1):90
pubmed: 30005597
Lab Chip. 2016 Jan 21;16(2):242-5
pubmed: 26621222
Trends Analyt Chem. 2009 Sep;28(8):925-942
pubmed: 32287534
Biosens Bioelectron. 2018 Sep 30;116:130-147
pubmed: 29879539
J Am Chem Soc. 2011 Nov 2;133(43):17149-51
pubmed: 21954996
Chem Soc Rev. 2015 May 21;44(10):2963-97
pubmed: 25739971
Biosens Bioelectron. 2018 Nov 30;120:144-152
pubmed: 30173010
Biomed Microdevices. 2014 Dec;16(6):905-14
pubmed: 25106501
Chem Commun (Camb). 2010 Jun 14;46(22):3896-8
pubmed: 20407665
Nucleic Acids Res. 2009 Feb;37(3):e20
pubmed: 19129227
Adv Mater. 2016 Jul;28(28):5907-15
pubmed: 27158947
Nat Chem. 2011 Jul 24;3(9):697-703
pubmed: 21860458
Genome Biol. 2015 Jul 23;16:148
pubmed: 26201400
Nat Biotechnol. 2017 Dec;35(12):1170-1178
pubmed: 29106407
Chem Rev. 2013 Aug 14;113(8):6207-33
pubmed: 23697835
Biosens Bioelectron. 2011 Jan 15;26(5):2045-52
pubmed: 20869865
Talanta. 2017 Mar 1;164:261-267
pubmed: 28107927
Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):11923-8
pubmed: 26340991
Nat Protoc. 2016 Jul;11(7):1244-63
pubmed: 27310264
ACS Appl Mater Interfaces. 2018 Aug 1;10(30):25621-25628
pubmed: 29969017
Anal Chem. 2011 Feb 15;83(4):1300-6
pubmed: 21247195
Cell. 2016 May 19;165(5):1255-1266
pubmed: 27160350
Clin Lab. 2015;61(9):1129-35
pubmed: 26554231
Nat Commun. 2019 Nov 7;10(1):5079
pubmed: 31699984
Proc Natl Acad Sci U S A. 2015 May 12;112(19):5903-8
pubmed: 25918425
ACS Sens. 2017 Jul 28;2(7):876-891
pubmed: 28750519
Angew Chem Int Ed Engl. 2007;46(8):1318-20
pubmed: 17211899
Chem Soc Rev. 2013 Jan 21;42(2):450-7
pubmed: 23032871
Angew Chem Int Ed Engl. 2014 Feb 24;53(9):2389-93
pubmed: 24469913
Biosens Bioelectron. 2015 Sep 15;71:7-12
pubmed: 25880832
Anal Chem. 2016 Dec 6;88(23):11384-11389
pubmed: 27800678
ACS Synth Biol. 2017 May 19;6(5):782-792
pubmed: 28094993
Proc Natl Acad Sci U S A. 2004 Oct 26;101(43):15275-8
pubmed: 15492210
Nucleic Acids Res. 1997 Apr 1;25(7):1442-9
pubmed: 9060442
Science. 2011 Jul 22;333(6041):470-4
pubmed: 21700839
Anal Chem. 2018 Jun 19;90(12):7107-7111
pubmed: 29847923
Annu Rev Anal Chem (Palo Alto Calif). 2017 Jun 12;10(1):439-462
pubmed: 28301747
J Am Chem Soc. 2009 Jul 29;131(29):9866-7
pubmed: 19572753
Biosensors (Basel). 2016 Aug 05;6(3):
pubmed: 27527231
Nucleic Acids Res. 2019 Dec 16;47(22):e145
pubmed: 31584096
Nat Rev Genet. 2010 Jan;11(1):31-46
pubmed: 19997069
Biotechnol Adv. 2011 Nov-Dec;29(6):830-9
pubmed: 21741465
Science. 1988 Jan 29;239(4839):487-91
pubmed: 2448875
ACS Nano. 2012 May 22;6(5):3974-81
pubmed: 22424140
Anal Chem. 2019 Sep 3;91(17):11403-11408
pubmed: 31414597
Anal Chem. 2019 Apr 2;91(7):4696-4701
pubmed: 30859815
Chem Sci. 2019 Oct 21;11(1):62-69
pubmed: 32110357
Theranostics. 2013 May 05;3(6):395-408
pubmed: 23781286
Chem Soc Rev. 2015 Nov 7;44(21):7829-54
pubmed: 26204249
Lab Chip. 2014 Feb 7;14(3):562-8
pubmed: 24297040
Biosystems. 2005 Jul;81(1):25-9
pubmed: 15917125
Nat Rev Genet. 2012 Sep;13(9):601-612
pubmed: 22868263
Nat Methods. 2014 Apr;11(4):360-1
pubmed: 24681720
Anal Chem. 2019 Dec 17;91(24):15694-15702
pubmed: 31725282
Biosens Bioelectron. 2019 Oct 15;143:111616
pubmed: 31472412
Anal Chem. 2009 Nov 1;81(21):9109-13
pubmed: 19810694
Sci Adv. 2016 Nov 23;2(11):e1600974
pubmed: 28138524
Anal Chem. 2013 Dec 3;85(23):11509-17
pubmed: 24206055
Spectrochim Acta A Mol Biomol Spectrosc. 2020 Feb 15;227:117529
pubmed: 31703998
Anal Chem. 2014 Jan 7;86(1):884-90
pubmed: 24328238
Nat Commun. 2019 Nov 29;10(1):5469
pubmed: 31784537
Biosens Bioelectron. 2020 Jan 1;147:111789
pubmed: 31655383
Anal Bioanal Chem. 2012 Jan;402(1):187-94
pubmed: 22052153
Food Chem. 2020 Mar 1;307:125534
pubmed: 31644980
Nat Methods. 2016 Jul;13(7):587-90
pubmed: 27159086
Nat Commun. 2018 Aug 6;9(1):3114
pubmed: 30082701
ACS Nano. 2014 Mar 25;8(3):2632-8
pubmed: 24528470
J Am Chem Soc. 2017 Aug 30;139(34):11752-11759
pubmed: 28762730
Chem Rev. 2010 Aug 11;110(8):4709-23
pubmed: 20583806
Cell. 2013 Sep 26;155(1):27-38
pubmed: 24074859
Proc Natl Acad Sci U S A. 2020 Feb 11;117(6):2886-2893
pubmed: 31988135
Chem Commun (Camb). 2014 Dec 28;50(100):15932-5
pubmed: 25381873
Anal Chem. 2017 May 16;89(10):5428-5435
pubmed: 28394582
Nano Lett. 2019 Jan 9;19(1):369-374
pubmed: 30511869
Angew Chem Int Ed Engl. 2019 Mar 18;58(12):3913-3917
pubmed: 30667127
J Mater Chem B. 2016 Mar 14;4(10):1757-1769
pubmed: 32263053
Mod Pathol. 2002 Jun;15(6):657-65
pubmed: 12065780
Anal Chem. 2009 Aug 15;81(16):7091-5
pubmed: 20337388
ACS Appl Mater Interfaces. 2019 May 1;11(17):16198-16206
pubmed: 30892007
Clin Chem. 2013 Dec;59(12):1691-3
pubmed: 24100808
Anal Chem. 2008 Dec 15;80(24):9402-10
pubmed: 19007191
Acc Chem Res. 2019 Dec 17;52(12):3275-3286
pubmed: 31721559
Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2056-61
pubmed: 17284609
Int J Mycobacteriol. 2014 Sep;3(3):205-10
pubmed: 26786489
Science. 2017 Dec 15;358(6369):
pubmed: 29242318
Anal Chim Acta. 2020 Feb 15;1098:56-65
pubmed: 31948587
Angew Chem Int Ed Engl. 2018 Mar 5;57(11):2768-2798
pubmed: 28521066
Science. 2018 Jul 27;361(6400):
pubmed: 29930089
Annu Rev Microbiol. 1990;44:625-48
pubmed: 2252397
Lab Chip. 2016 Jan 7;16(1):199-207
pubmed: 26610171
Lab Chip. 2011 Apr 7;11(7):1286-91
pubmed: 21243159
Angew Chem Int Ed Engl. 2012 May 29;51(22):5497-501
pubmed: 22511466
Anal Chem. 2019 Jul 2;91(13):8549-8557
pubmed: 31247732
Chem Sci. 2019 Jun 28;10(31):7466-7471
pubmed: 31489169
Biosens Bioelectron. 2016 May 15;79:220-36
pubmed: 26708241
J Mol Evol. 2015 Dec;81(5-6):150-61
pubmed: 26530075
Clin Chim Acta. 2015 Jan 15;439:231-50
pubmed: 25451956
Anal Chem. 2017 Apr 4;89(7):4153-4160
pubmed: 28271879
J Am Chem Soc. 2020 Jun 3;142(22):9975-9981
pubmed: 32369359
Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14173-14175
pubmed: 27911833
Sci Rep. 2016 Nov 25;6:37732
pubmed: 27886248
ACS Nano. 2011 May 24;5(5):4236-44
pubmed: 21520951
Nucleic Acids Res. 2015 Jul 13;43(12):6125-33
pubmed: 25990730
Angew Chem Int Ed Engl. 2014 Feb 10;53(7):1845-8
pubmed: 24402831
Mol Cell. 2019 Jan 3;73(1):130-142.e5
pubmed: 30472192
Mass Spectrom Rev. 1996;15(2):67-138
pubmed: 27082318
J Am Chem Soc. 2013 May 29;135(21):7967-73
pubmed: 23642046
Sci Adv. 2017 Mar 22;3(3):e1501645
pubmed: 28345028
Biosens Bioelectron. 1998 Oct 1;13(7-8):757-62
pubmed: 9828369
Nature. 1999 Jun 10;399(6736):533-4
pubmed: 10376592
Nat Chem. 2011 Feb;3(2):103-13
pubmed: 21258382
Cell. 1977 Sep;12(1):23-36
pubmed: 198139
Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9134-7
pubmed: 12867594
Angew Chem Int Ed Engl. 2010;49(2):355-8
pubmed: 19967683
Analyst. 2012 Aug 21;137(16):3821-7
pubmed: 22773999
Anal Chem. 2017 Oct 3;89(19):10468-10473
pubmed: 28810735
Nature. 2017 Oct 19;550(7676):345-353
pubmed: 29019985
Lab Chip. 2019 Sep 7;19(17):2769-2785
pubmed: 31365009
J Appl Microbiol. 2003;95(6):1343-50
pubmed: 14633009
Mikrochim Acta. 2014 Apr;181(5-6):479-491
pubmed: 25419005
Expert Rev Mol Diagn. 2001 May;1(1):1-5
pubmed: 11901792
Nucleic Acids Res. 1997 Jul 15;25(14):2816-22
pubmed: 9207029
ACS Nano. 2020 Feb 25;14(2):2497-2508
pubmed: 32045522
Anal Chem. 2017 Jan 3;89(1):728-735
pubmed: 28105843
Chem Sci. 2018 Jun 15;9(27):5967-5975
pubmed: 30079211
Nat Commun. 2019 Feb 5;10(1):608
pubmed: 30723214
Nat Methods. 2019 Mar;16(3):225-234
pubmed: 30804549
Anal Chem. 2020 Jul 21;92(14):9895-9900
pubmed: 32551560
Lab Chip. 2018 Sep 11;18(18):2749-2756
pubmed: 30123896
Anal Chem. 2015 Jan 20;87(2):929-36
pubmed: 25494977
Science. 2014 Mar 21;343(6177):1360-3
pubmed: 24578530
Clin Cancer Res. 2014 Mar 15;20(6):1428-44
pubmed: 24634466
J Mol Med (Berl). 2018 Jan;96(1):85-96
pubmed: 29098316
Integr Biol (Camb). 2017 Mar 1;9(3):188-205
pubmed: 28144664
Nat Protoc. 2017 Jun;12(6):1198-1228
pubmed: 28518172
Mol Ther. 2014 Jul;22(7):1375-1387
pubmed: 24682172
Theranostics. 2017 Jun 1;7(8):2220-2230
pubmed: 28740546
Angew Chem Int Ed Engl. 2015 Sep 1;54(36):10448-53
pubmed: 26180027
Lab Chip. 2013 Jun 21;13(12):2210-51
pubmed: 23652632
Chem Biol. 1994 Dec;1(4):223-9
pubmed: 9383394
Chem Rev. 2012 Apr 11;112(4):2528-56
pubmed: 22233123
Nat Rev Genet. 2019 Apr;20(4):235-248
pubmed: 30647469
Proc Natl Acad Sci U S A. 2014 May 13;111(19):7048-53
pubmed: 24782542
Angew Chem Int Ed Engl. 2012 Jul 23;51(30):7426-30
pubmed: 22806948
Angew Chem Int Ed Engl. 2008;47(23):4346-50
pubmed: 18435522
Chem Soc Rev. 2015 May 21;44(10):3036-55
pubmed: 25777303
Curr Opin Biotechnol. 2017 Jun;45:191-201
pubmed: 28458112
Analyst. 2015 Nov 21;140(22):7540-9
pubmed: 26393240
Nat Commun. 2020 Jan 14;11(1):267
pubmed: 31937772
Nat Rev Genet. 2016 May 17;17(6):333-51
pubmed: 27184599
Anal Chem. 2018 Jan 16;90(2):1087-1091
pubmed: 29231705
Anal Chem. 2008 May 15;80(10):3699-707
pubmed: 18407617
Biomicrofluidics. 2012 Mar;6(1):11301-1130113
pubmed: 22662067
Angew Chem Int Ed Engl. 2012 Jul 9;51(28):6925-8
pubmed: 22639438
Bioconjug Chem. 2015 Nov 18;26(11):2186-97
pubmed: 26083153
Nat Biotechnol. 2019 Jan 3;37(1):102
pubmed: 30605160
Biosens Bioelectron. 2013 Sep 15;47:524-9
pubmed: 23643946
ACS Nano. 2016 Jun 28;10(6):6201-10
pubmed: 27299807
Anal Chem. 2019 Nov 5;91(21):14043-14048
pubmed: 31577421
Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):E1866-E1874
pubmed: 28223521
Nat Rev Genet. 2019 Nov;20(11):631-656
pubmed: 31341269
J Am Chem Soc. 2013 Jun 19;135(24):9121-9
pubmed: 23679108
ACS Nano. 2020 Feb 25;14(2):1319-1337
pubmed: 31976651
ACS Nano. 2017 Apr 25;11(4):3532-3541
pubmed: 28264152
J Am Chem Soc. 2007 Feb 7;129(5):1042-3
pubmed: 17263380
Curr Opin Biotechnol. 2017 Jun;45:15-23
pubmed: 28088092
Nat Protoc. 2011 Jun;6(6):772-8
pubmed: 21637197
Talanta. 2013 Oct 15;115:133-42
pubmed: 24054570
ACS Nano. 2017 Dec 26;11(12):11908-11914
pubmed: 29045785
Chem Biol. 1998 Sep;5(9):505-17
pubmed: 9751647
Annu Rev Biomed Eng. 2008;10:107-44
pubmed: 18358075
Lancet. 2018 Sep 1;392(10149):777-786
pubmed: 30100054
Nature. 2006 Mar 16;440(7082):297-302
pubmed: 16541064
Nucleic Acids Res. 2016 Jun 20;44(11):e105
pubmed: 27060140
Anal Chem. 2011 Jun 15;83(12):4327-41
pubmed: 21612267
J Am Chem Soc. 2020 Jan 8;142(1):207-213
pubmed: 31800219
Small. 2017 Mar;13(10):
pubmed: 28026123
Chem Commun (Camb). 2020 Sep 11;56(70):10235-10238
pubmed: 32756614
Anal Chem. 2020 Jan 21;92(2):2301-2309
pubmed: 31845797
J Am Chem Soc. 2013 May 22;135(20):7430-3
pubmed: 23647466
ACS Nano. 2020 Jan 28;14(1):28-117
pubmed: 31478375
Nano Lett. 2020 Mar 11;20(3):1477-1478
pubmed: 32011893
Small. 2016 Jan 13;12(2):205-13
pubmed: 26578391
Trends Microbiol. 2002;10(10 Suppl):S15-21
pubmed: 12377563
J Am Chem Soc. 2009 Dec 23;131(50):18048-9
pubmed: 19950958
Angew Chem Int Ed Engl. 2011 Apr 11;50(16):3751-4
pubmed: 21412961
Mikrochim Acta. 2019 Dec 7;187(1):29
pubmed: 31813061
Mol Biotechnol. 2007 Nov;37(3):246-57
pubmed: 17952671
Nat Nanotechnol. 2016 Dec;11(12):1112-1119
pubmed: 27548358
J Am Chem Soc. 2010 Oct 20;132(41):14346-8
pubmed: 20873767
Mol Oncol. 2012 Dec;6(6):567-78
pubmed: 22902148
Adv Mater. 2019 Feb;31(6):e1805875
pubmed: 30556205
Sci Technol Adv Mater. 2013 Aug 6;14(4):044404
pubmed: 27877589
Nat Rev Drug Discov. 2017 Feb;16(2):131-147
pubmed: 27932801
Nat Rev Genet. 2018 Mar;19(3):175-185
pubmed: 29151588
Nature. 1986 Jun 12-18;321(6071):674-9
pubmed: 3713851
Clin Biochem. 2015 Oct;48(15):948-56
pubmed: 25828047
Chem Rev. 2019 Nov 27;119(22):11631-11717
pubmed: 31573184
Nature. 2005 Sep 15;437(7057):376-80
pubmed: 16056220
Chem Soc Rev. 2008 Apr;37(4):648-63
pubmed: 18362974
J Am Chem Soc. 2013 Mar 13;135(10):3748-51
pubmed: 23339662
Chem Rev. 2007 Sep;107(9):3715-43
pubmed: 17715981
Angew Chem Int Ed Engl. 2015 Nov 2;54(45):13214-8
pubmed: 26337144
ACS Appl Mater Interfaces. 2016 Oct 19;8(41):27772-27778
pubmed: 27696801
N Engl J Med. 2018 Aug 2;379(5):464-473
pubmed: 30067923
Nucleic Acids Res. 1997 Oct 1;25(19):3925-9
pubmed: 9380518
Nat Commun. 2017 Dec 12;8(1):2090
pubmed: 29233999
Clin Chem. 2013 Dec;59(12):1722-31
pubmed: 23938455
Biosens Bioelectron. 2019 Mar 1;128:151-158
pubmed: 30660930
Biosens Bioelectron. 2016 Nov 15;85:247-260
pubmed: 27179566
Nat Methods. 2013 Jul;10(7):641-6
pubmed: 23749303
Science. 2012 Feb 17;335(6070):831-4
pubmed: 22344439
Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2233-7
pubmed: 9482868
Nature. 1995 Jun 15;375(6532):611-4
pubmed: 7791880
Front Chem. 2014 Jun 26;2:41
pubmed: 25019067
Nature. 2008 Nov 6;456(7218):53-9
pubmed: 18987734
Lab Chip. 2010 Apr 7;10(7):887-93
pubmed: 20300675
J Am Chem Soc. 2008 Aug 27;130(34):11268-9
pubmed: 18680291
Anal Chem. 2019 Jan 15;91(2):1222-1226
pubmed: 30569701
Anal Chem. 2019 Oct 1;91(19):12581-12586
pubmed: 31539224
Adv Mater. 2017 Nov;29(42):
pubmed: 28980743
Nucleic Acids Res. 2011 Jul;39(12):e80
pubmed: 21486750
Nature. 2008 Jan 17;451(7176):318-22
pubmed: 18202654
Biosens Bioelectron. 2017 May 15;91:334-340
pubmed: 28043075
Nat Nanotechnol. 2007 May;2(5):275-84
pubmed: 18654284
Commun Biol. 2019 Apr 29;2:147
pubmed: 31044172
Chem Sci. 2016 Aug 1;7(8):5495-5502
pubmed: 30034689
J Am Chem Soc. 2018 Feb 21;140(7):2478-2484
pubmed: 29406750
Analyst. 2013 Feb 21;138(3):907-15
pubmed: 23230566
Angew Chem Int Ed Engl. 2018 Jun 11;57(24):7131-7135
pubmed: 29603524
Nucleic Acids Res. 2011 Mar;39(6):2458-69
pubmed: 21030439
Chem Soc Rev. 2016 May 3;45(9):2583-602
pubmed: 26954935
Anal Chem. 2019 Nov 19;91(22):14254-14260
pubmed: 31595744
Anal Chem. 2011 May 1;83(9):3352-7
pubmed: 21462922
Anal Chem. 2019 Dec 17;91(24):15899-15907
pubmed: 31743646
Biosens Bioelectron. 2018 May 15;105:218-225
pubmed: 29412946
Nat Rev Genet. 2020 Mar;21(3):171-189
pubmed: 31729472
Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17104-9
pubmed: 25404304
Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5386-91
pubmed: 23509255
Nature. 2016 Feb 11;530(7589):228-232
pubmed: 26840485
Nat Biotechnol. 2014 Mar;32(3):261-266
pubmed: 24561555
Science. 2014 Aug 15;345(6198):799-804
pubmed: 25124436
Sci Rep. 2017 Sep 26;7(1):12335
pubmed: 28951563
Lancet. 2005 Jul 9-15;366(9480):123-8
pubmed: 16005334
Chem Rev. 2015 Nov 25;115(22):12491-545
pubmed: 26551336
Nat Protoc. 2008;3(5):877-82
pubmed: 18451795
J Am Chem Soc. 2013 Mar 27;135(12):4604-7
pubmed: 23445447
J Am Chem Soc. 2015 Aug 26;137(33):10576-84
pubmed: 26258907
ACS Appl Mater Interfaces. 2017 Jul 19;9(28):23287-23301
pubmed: 28632380
Anal Chem. 2012 Jun 19;84(12):5392-9
pubmed: 22632712
Angew Chem Int Ed Engl. 2015 Feb 9;54(7):2151-5
pubmed: 25556850
Anal Chem. 2020 Mar 3;92(5):3867-3873
pubmed: 32069024
Lab Chip. 2016 Oct 5;16(20):3866-3884
pubmed: 27713993
J Am Chem Soc. 2015 Apr 22;137(15):4900-3
pubmed: 25835750
Cancer Cell. 2015 Nov 9;28(5):666-676
pubmed: 26525104
Biosens Bioelectron. 2015 Dec 15;74:836-42
pubmed: 26232679
Anal Chem. 2013 Dec 3;85(23):11634-42
pubmed: 24206087
Anal Chem. 2014 Aug 19;86(16):8418-24
pubmed: 25048399
Nano Lett. 2006 Oct;6(10):2225-31
pubmed: 17034088
Appl Microbiol Biotechnol. 2018 Dec;102(24):10377-10391
pubmed: 30302518
Anal Chem. 2018 Jun 19;90(12):7221-7229
pubmed: 29761701
Anal Chem. 2013 Nov 5;85(21):10581-8
pubmed: 24088027
Annu Rev Biophys Biomol Struct. 1998;27:225-48
pubmed: 9646868
Anal Chem. 2018 Feb 20;90(4):2570-2577
pubmed: 29350029
Chem Rev. 2014 Aug 13;114(15):7631-77
pubmed: 25115973
Anal Chem. 2010 Jan 1;82(1):3-10
pubmed: 20000334
Chem Soc Rev. 2014 Sep 7;43(17):6239-53
pubmed: 24882068
Angew Chem Int Ed Engl. 2020 Feb 10;59(7):2628-2633
pubmed: 31793153
Chem Sci. 2017 Jul 1;8(7):4764-4770
pubmed: 28959399
Anal Chem. 2009 Jul 15;81(14):5821-6
pubmed: 19485415
Nucleic Acids Res. 2018 Nov 2;46(19):10262-10271
pubmed: 30215808
Cell. 2018 Feb 22;172(5):1091-1107.e17
pubmed: 29474909
Angew Chem Int Ed Engl. 2018 Apr 16;57(17):4549-4553
pubmed: 29504183
Nat Nanotechnol. 2008 Jul;3(7):418-22
pubmed: 18654566
Anal Chem. 2005 Apr 15;77(8):2381-5
pubmed: 15828770
Angew Chem Int Ed Engl. 2016 Feb 24;55(9):3073-6
pubmed: 26694689
Biomacromolecules. 2011 Jun 13;12(6):2008-15
pubmed: 21568314
J Am Chem Soc. 2019 Nov 27;141(47):18910-18915
pubmed: 31691568
Sci Rep. 2017 Jan 17;7:38896
pubmed: 28094255
Nat Methods. 2013 Feb;10(2):171-7
pubmed: 23314172
Science. 2004 Dec 17;306(5704):2068-72
pubmed: 15604402
Anal Chem. 2012 Jun 19;84(12):5407-14
pubmed: 22612343
ACS Appl Mater Interfaces. 2016 Nov 9;8(44):29939-29949
pubmed: 27759378
Nucleic Acids Res. 1997 Nov 15;25(22):4500-4
pubmed: 9358158
Biosens Bioelectron. 2019 Nov 1;144:111635
pubmed: 31513958
Nat Genet. 2014 Dec;46(12):1343-9
pubmed: 25326703
Nature. 2012 May 30;485(7400):623-6
pubmed: 22660323
Angew Chem Int Ed Engl. 2010 Feb 1;49(6):1052-6
pubmed: 20084650
Biosens Bioelectron. 2010 Dec 15;26(4):1624-30
pubmed: 20864333
Forensic Sci Int Genet. 2015 Sep;18:140-51
pubmed: 25934544
Anal Chem. 2014 Mar 4;86(5):2285-8
pubmed: 24528092
Forensic Sci Int. 2010 Dec 15;203(1-3):106-11
pubmed: 20674199
Nat Methods. 2018 Apr;15(4):275-278
pubmed: 29481551
Expert Rev Mol Diagn. 2015;15(9):1187-200
pubmed: 26189641
Angew Chem Int Ed Engl. 2011 Jan 3;50(1):295-9
pubmed: 21082638
Anal Chem. 2019 Jan 2;91(1):743-756
pubmed: 30212618
Anal Biochem. 1989 Dec;183(2):220-4
pubmed: 2696384
Biomicrofluidics. 2013 Jan;7(1):11302
pubmed: 23460772
ACS Sens. 2018 Jan 26;3(1):174-182
pubmed: 29282979
Nat Commun. 2020 Feb 11;11(1):838
pubmed: 32047166
Chem Rev. 2017 Jun 28;117(12):8272-8325
pubmed: 28598605
J Am Chem Soc. 2016 Jan 13;138(1):306-12
pubmed: 26691742
Nucleic Acids Res. 1997 Jan 1;25(1):7-14
pubmed: 9016493
Biosens Bioelectron. 2017 Dec 15;98:227-233
pubmed: 28688308
ACS Nano. 2014 May 27;8(5):4902-7
pubmed: 24766422
Biosens Bioelectron. 2018 Apr 15;102:582-588
pubmed: 29241062
Angew Chem Int Ed Engl. 2019 Aug 19;58(34):11574-11585
pubmed: 30707484
Small. 2015 Nov 18;11(43):5800-6
pubmed: 26382921
Methods Mol Biol. 2017;1500:51-80
pubmed: 27813001
ACS Appl Mater Interfaces. 2012 Dec;4(12):6450-3
pubmed: 23182299
Biosens Bioelectron. 2012 Oct-Dec;38(1):195-201
pubmed: 22776181
Appl Environ Microbiol. 2013 May;79(10):3148-55
pubmed: 23475615
Angew Chem Int Ed Engl. 2020 Feb 24;59(9):3573-3577
pubmed: 31867832
J Am Chem Soc. 2003 Jun 4;125(22):6642-3
pubmed: 12769568
Nanoscale. 2010 Jun;2(6):1021-6
pubmed: 20648302
Lab Chip. 2016 Sep 21;16(18):3524-31
pubmed: 27460504
Chem Rev. 2015 Oct 14;115(19):10530-74
pubmed: 26313138
Adv Mater. 2020 Apr;32(13):e1901743
pubmed: 31271253
Biochem J. 1944;38(3):224-32
pubmed: 16747784
Trends Analyt Chem. 2011 Nov;30(10):1587-1597
pubmed: 32287535
Angew Chem Int Ed Engl. 2018 Aug 13;57(33):10544-10548
pubmed: 29885071
ACS Chem Biol. 2010 Nov 19;5(11):1065-74
pubmed: 20809562
Anal Chem. 2014 Jun 17;86(12):6166-70
pubmed: 24871788
Chemistry. 2016 Jul 11;22(29):9886-900
pubmed: 27243551
Appl Microbiol Biotechnol. 2015 May;99(10):4119-29
pubmed: 25808518
Anal Chem. 2016 Nov 15;88(22):10795-10799
pubmed: 27783484
Science. 2005 Sep 9;309(5741):1728-32
pubmed: 16081699
J Am Chem Soc. 2019 May 1;141(17):7056-7062
pubmed: 30929430
J Am Chem Soc. 2016 Aug 31;138(34):11009-16
pubmed: 27513828
Lab Chip. 2018 Feb 13;18(4):610-619
pubmed: 29379939
Biosens Bioelectron. 2019 Oct 1;142:111525
pubmed: 31369944
Anal Chem. 1996 Jul 1;68(13):1989-99
pubmed: 9027217
Lab Chip. 2016 Aug 2;16(16):3097-104
pubmed: 27302553
Nat Biomed Eng. 2019 Sep;3(9):684-694
pubmed: 31285580
Nat Rev Clin Oncol. 2019 Feb;16(2):81-104
pubmed: 30356138
Anal Chem. 2019 Dec 17;91(24):15740-15747
pubmed: 31714070
J Am Chem Soc. 2020 Feb 12;142(6):2889-2896
pubmed: 31986025
Adv Mater. 2019 Dec;31(51):e1905311
pubmed: 31663165
Biosens Bioelectron. 2018 Feb 15;100:96-104
pubmed: 28869845
Anal Chem. 2016 Aug 2;88(15):7813-20
pubmed: 27373463
BMC Cancer. 2014 Jul 19;14:519
pubmed: 25037456
Oncotarget. 2015 Sep 8;6(26):22270-81
pubmed: 26045302
Angew Chem Int Ed Engl. 2008;47(34):6330-7
pubmed: 18680110
Angew Chem Int Ed Engl. 2019 Dec 9;58(50):18271-18275
pubmed: 31591798
Nature. 2011 Jul 20;475(7356):348-52
pubmed: 21776081
Luminescence. 2019 May;34(3):308-315
pubmed: 30690847
Annu Rev Med. 2016;67:419-32
pubmed: 26473414
Science. 2017 Apr 14;356(6334):189-194
pubmed: 28408603
Proc Natl Acad Sci U S A. 2010 Jun 15;107(24):10837-41
pubmed: 20534499
Biosens Bioelectron. 2017 May 15;91:441-448
pubmed: 28064129
Biosens Bioelectron. 2017 Apr 15;90:459-474
pubmed: 27818047
Expert Rev Mol Diagn. 2011 Jan;11(1):9-12
pubmed: 21171915
Anal Chem. 2013 Dec 17;85(24):11929-35
pubmed: 24191690
Front Biosci (Schol Ed). 2019 Mar 1;11(1):122-135
pubmed: 30844740
Analyst. 2009 Feb;134(2):314-9
pubmed: 19173055
Chem Sci. 2018 Jul 23;9(32):6605-6613
pubmed: 30310592
J Clin Microbiol. 2018 Oct 25;56(11):
pubmed: 30135232
Nanoscale. 2016 Aug 11;8(32):15008-15
pubmed: 27468834
Angew Chem Int Ed Engl. 2012 Feb 6;51(6):1316-32
pubmed: 22213382
ACS Appl Mater Interfaces. 2018 Apr 18;10(15):12526-12533
pubmed: 29624369
Anal Bioanal Chem. 2016 Dec;408(30):8611-8620
pubmed: 27220649
Anal Biochem. 2011 Oct 1;417(1):73-9
pubmed: 21693099
Trends Biotechnol. 2019 Dec;37(12):1367-1382
pubmed: 31679827
Anal Chem. 2018 Feb 6;90(3):2271-2276
pubmed: 29295617
Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19606-11
pubmed: 19064929
Adv Mater. 2016 Aug;28(32):6860-5
pubmed: 27218679
ACS Appl Mater Interfaces. 2019 Feb 27;11(8):7792-7799
pubmed: 30714711
Nucleic Acids Res. 1997 Jan 1;25(1):1-6
pubmed: 9016491
Analyst. 2008 Jul;133(7):846-54
pubmed: 18575633
ACS Appl Mater Interfaces. 2017 Aug 2;9(30):25107-25113
pubmed: 28696099
Chem Rev. 2013 Apr 10;113(4):2842-62
pubmed: 23509854
Proc Natl Acad Sci U S A. 1998 May 26;95(11):6027-31
pubmed: 9600911
Angew Chem Int Ed Engl. 2010 Jul 26;49(32):5498-501
pubmed: 20602382
Sci Rep. 2015 Dec 22;5:18478
pubmed: 26690672
J Am Chem Soc. 2006 Jul 5;128(26):8575-80
pubmed: 16802824