A risk scoring tool for predicting Kenyan women at high risk of contraceptive discontinuation.
Contraception
Discontinuation
Family planning
LMIC
Risk score
Unmet need
Journal
Contraception: X
ISSN: 2590-1516
Titre abrégé: Contracept X
Pays: United States
ID NLM: 101767748
Informations de publication
Date de publication:
2020
2020
Historique:
received:
24
03
2020
revised:
12
10
2020
accepted:
13
10
2020
entrez:
9
12
2020
pubmed:
10
12
2020
medline:
10
12
2020
Statut:
epublish
Résumé
We developed and validated a pragmatic risk assessment tool for identifying contraceptive discontinuation among Kenyan women who do not desire pregnancy. Within a prospective cohort of contraceptive users, participants were randomly allocated to derivation ( The overall contraceptive discontinuation rate was 36.9 per 100 woman-years (95% confidence interval [CI] 30.3-44.9). The predictors of discontinuation selected for the risk score included use of a short-term method or copper intrauterine device (vs. injectable or implant), method continuation or switch (vs. initiation), < 9 years of completed education, not having a child aged < 6 months, and having no spouse or a spouse supportive of family planning (vs. having a spouse who has unsupportive or uncertain attitudes towards family planning). AUC at 24 weeks was 0.76 (95% CI 0.64-0.87) with 70.0% sensitivity and 78.6% specificity at the optimal cut point in the derivation cohort. Discontinuation was 3.8-fold higher among high- vs. low-risk women (95% CI 2.33-6.30). AUC was 0.68 (95% CI 0.47-0.90) in the validation cohort. A simplified score comprising routinely collected variables demonstrated similar performance (derivation-AUC: 0.73 [95% CI 0.60-0.85]; validation-AUC: 0.73 [95% CI 0.51-0.94]). Positive predictive value in the derivation cohort was 31.4% for the full and 28.1% for the simplified score. The risk scores demonstrated moderate predictive ability but identified large proportions of women as high risk. Future research is needed to improve sensitivity and specificity of a clinical tool to identify women at high risk for experiencing method-related challenges. Contraceptive discontinuation is a major driver of unmet contraceptive need globally. Few tools exist for identifying women who may benefit most from additional support in order to meet their contraceptive needs and preferences. This study developed and assessed the validity of a provider-focused risk prediction tool for contraceptive discontinuation among Kenyan women using modern contraception. High rates of early discontinuation observed in this study emphasize the necessity of investing in efforts to develop new contraceptive technologies and stronger delivery systems to better align with women's needs and preferences for voluntary family planning.
Identifiants
pubmed: 33294838
doi: 10.1016/j.conx.2020.100045
pii: S2590-1516(20)30028-9
pmc: PMC7683324
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100045Subventions
Organisme : NICHD NIH HHS
ID : F32 HD100202
Pays : United States
Organisme : NIAID NIH HHS
ID : K01 AI116298
Pays : United States
Informations de copyright
© 2020 The Authors.
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