No increased bleeding events in patients with relapsed chronic lymphocytic leukemia and indolent non-Hodgkin lymphoma treated with idelalisib.


Journal

Leukemia & lymphoma
ISSN: 1029-2403
Titre abrégé: Leuk Lymphoma
Pays: United States
ID NLM: 9007422

Informations de publication

Date de publication:
04 2021
Historique:
pubmed: 11 12 2020
medline: 1 5 2021
entrez: 10 12 2020
Statut: ppublish

Résumé

The advent of novel B-cell receptor pathway targeting agents like ibrutinib dramatically changed management of B-cell malignancies. However, with concomitant anticoagulation (AC) and antiplatelet (AP) therapy, ibrutinib is associated with increased bleeding. This

Identifiants

pubmed: 33297794
doi: 10.1080/10428194.2020.1845339
doi:

Substances chimiques

Antineoplastic Agents 0
Purines 0
Quinazolinones 0
idelalisib YG57I8T5M0

Banques de données

ClinicalTrials.gov
['NCT01282424', 'NCT01539512']

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

837-845

Subventions

Organisme : NCATS NIH HHS
ID : UL1 TR002384
Pays : United States

Auteurs

Jacqueline C Barrientos (JC)

Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.

Peter Hillmen (P)

St. James's University Hospital, Leeds, UK.

Gilles Salles (G)

Hospices Civils de Lyon, University Claude Bernard, Pierre Benite, France.

Jeff Sharman (J)

Willamette Valley Cancer Institute and Research Center/US Oncology Research, Springfield, OR, USA.

Stephan Stilgenbauer (S)

Department of Medicine III, University of Ulm, Ulm, Germany.

Oksana Gurtovaya (O)

Gilead Sciences, Inc, Foster City, CA, USA.

Guan Xing (G)

Gilead Sciences, Inc, Foster City, CA, USA.

Bianca Ruzicka (B)

Gilead Sciences, Inc, Foster City, CA, USA.

Pankaj Bhargava (P)

Gilead Sciences, Inc, Foster City, CA, USA.

Paolo Ghia (P)

Università Vita-Salute San Raffaele and IRCCS Instituto Scientifico San Raffaele, Milano, Italy.

John M Pagel (JM)

Swedish Cancer Institute, Seattle, WA, USA.

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Classifications MeSH