Stronger tilt aftereffects in persons with schizophrenia.
Journal
Journal of abnormal psychology
ISSN: 1939-1846
Titre abrégé: J Abnorm Psychol
Pays: United States
ID NLM: 0034461
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
pubmed:
11
12
2020
medline:
11
5
2021
entrez:
10
12
2020
Statut:
ppublish
Résumé
Individuals with schizophrenia may fail to appropriately use temporal context and apply past environmental regularities to the interpretation of incoming sensory information. Here we use the visual system as a test bed for investigating how prior experience shapes perception in individuals with schizophrenia. Specifically, we use visual aftereffects, illusory percepts resulting from prior exposure to visual input, to measure the influence of prior events on current processing. At a neural level, visual aftereffects arise due to attenuation in the responses of neurons that code the features of the prior stimulus (neuronal adaptation) and subsequent disinhibition of neurons signaling activity at the opposite end of the feature dimension. In the current study, we measured tilt aftereffects and negative afterimages, 2 types of aftereffects that reflect, respectively, adaptation of cortical orientation-coding neurons and adaptation of subcortical and retinal luminance-coding cells in persons with schizophrenia (PSZ; n = 36) and demographically matched healthy controls (HC; n = 22). We observed stronger tilt aftereffects in PSZ compared to HC, but no difference in negative afterimages. Stronger tilt aftereffects were related to more severe negative symptoms. These data suggest oversensitivity to recent regularities, in the form of stronger visual adaptation, at cortical, but not subcortical, levels in schizophrenia. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
Identifiants
pubmed: 33301337
pii: 2020-94557-001
doi: 10.1037/abn0000653
pmc: PMC8100990
mid: NIHMS1696938
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
186-197Subventions
Organisme : NIMH NIH HHS
ID : R01 MH112644
Pays : United States
Organisme : National Institutes of Mental Health
Organisme : Michigan State University; College of Social Science
Références
Schizophr Res. 2006 Sep;86(1-3):89-98
pubmed: 16829048
Neuropsychobiology. 2009;60(3-4):204-12
pubmed: 19893337
J Opt Soc Am A. 1993 Jan;10(1):29-37
pubmed: 8478743
Neurosci Biobehav Rev. 2005;29(6):977-88
pubmed: 15964074
J Neurosci. 2017 Feb 22;37(8):1984-1996
pubmed: 28077727
Vision Res. 2007 Oct;47(23):2923-33
pubmed: 17825350
Behav Res Methods. 2019 Feb;51(1):195-203
pubmed: 30734206
Schizophr Res. 2019 May;207:48-57
pubmed: 29685421
Biol Psychiatry. 2008 Jul 1;64(1):40-7
pubmed: 18549875
Hum Psychopharmacol. 2012 Mar;27(2):226-34
pubmed: 22389087
J Physiol. 1962 Oct;164:168-79
pubmed: 14015499
Neuron. 2017 Apr 5;94(1):153-167.e8
pubmed: 28384469
J Neurophysiol. 2007 May;97(5):3155-64
pubmed: 17344377
Biol Psychiatry. 2017 May 15;81(10):818-820
pubmed: 28063469
Biol Psychiatry. 2017 Mar 15;81(6):525-535
pubmed: 27316853
Nebr Symp Motiv. 1984;31:231-82
pubmed: 6728074
Neuropsychiatr Dis Treat. 2014 Jan 16;10:97-110
pubmed: 24476630
Neurosci Biobehav Rev. 2019 Jun;101:68-77
pubmed: 30940436
Neurosci Biobehav Rev. 2008;32(4):611-56
pubmed: 18061262
J Ophthalmic Vis Res. 2012 Jan;7(1):105-6
pubmed: 22737398
J Clin Psychol. 1974 Oct;30(4):513-6
pubmed: 4425268
Trends Cogn Sci. 2002 Mar 1;6(3):136-143
pubmed: 11861192
Nat Rev Neurosci. 2007 Jul;8(7):522-35
pubmed: 17585305
Vision Res. 1985;25(11):1709-20
pubmed: 3832595
J Vis. 2018 Jul 2;18(7):3
pubmed: 29971348
Schizophr Res. 2020 Apr 11;:
pubmed: 32291128
Eur J Neurosci. 2013 Jul;38(1):2065-77
pubmed: 23581614
Hum Brain Mapp. 2017 Apr;38(4):1767-1779
pubmed: 28097738
Curr Opin Pharmacol. 2011 Feb;11(1):59-67
pubmed: 21420906
Vision Res. 1989;29(1):129-35
pubmed: 2773330
PLoS One. 2013 Apr 09;8(4):e60951
pubmed: 23585865
Vision Res. 1977;17(7):853-60
pubmed: 898691
Neural Comput. 2000 Jul;12(7):1721-40
pubmed: 10935924
Psychol Rev. 2019 Apr;126(3):374-394
pubmed: 30688472
Science. 2008 Apr 18;320(5874):385-8
pubmed: 18420937
Neurosci Biobehav Rev. 2010 Apr;34(5):689-700
pubmed: 19559045
Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):13401-6
pubmed: 26460044
Neural Comput. 1998 May 15;10(4):903-40
pubmed: 9573412
Nebr Symp Motiv. 2016;63:77-132
pubmed: 27627825
Percept Mot Skills. 1990 Apr;70(2):531-9
pubmed: 2342851
Nat Rev Neurosci. 2009 Jan;10(1):48-58
pubmed: 19050712
Can J Psychiatry. 2005 Apr;50(5):247-57
pubmed: 15968839
Proc Biol Sci. 2000 Sep 7;267(1454):1705-10
pubmed: 12233765
J Cogn Neurosci. 2010 Oct;22(10):2326-44
pubmed: 19929762
Schizophr Bull. 2009 Nov;35(6):1078-84
pubmed: 19620601
Schizophr Bull. 1988;14(2):297-315
pubmed: 3059473
Cell Rep. 2016 Sep 27;17(1):58-68
pubmed: 27681421
Front Hum Neurosci. 2011 Nov 04;5:127
pubmed: 22069385
Arch Gen Psychiatry. 1962 Aug;7:114-9
pubmed: 13925291
Science. 2001 Aug 31;293(5535):1677-80
pubmed: 11533495
J Neurosci. 2006 Nov 1;26(44):11403-12
pubmed: 17079669
Biol Psychiatry. 2010 Feb 1;67(3):255-62
pubmed: 19897178
Q J Exp Psychol. 1972 Feb;24(1):1-7
pubmed: 4622800
Psychopharmacology (Berl). 1983;79(1):49-57
pubmed: 6403965
Cereb Cortex. 2013 Aug;23(8):1849-58
pubmed: 22735157
J Opt Soc Am. 1982 Sep;72(9):1232-7
pubmed: 7131117
Vision Res. 1990;30(11):1561-71
pubmed: 2288075
J Neuropsychiatry Clin Neurosci. 2002 Spring;14(2):190-6
pubmed: 11983794
Schizophr Res. 2002 Jan 1;53(1-2):101-8
pubmed: 11728843
Arch Gen Psychiatry. 2005 May;62(5):495-504
pubmed: 15867102
Vision Res. 1975 Aug-Sep;15:967-72
pubmed: 1166632
Curr Biol. 2005 Oct 25;15(20):R822-4
pubmed: 16243017
Clin Psychol Sci. 2013 Jan 1;1(1):5-15
pubmed: 23997995
Neuropsychologia. 1971 Mar;9(1):97-113
pubmed: 5146491
J Vis. 2010 Jan 19;10(1):8.1-13
pubmed: 20143901
Curr Biol. 2009 Jan 13;19(1):R11-4
pubmed: 19138580
Biol Psychiatry. 2018 Nov 1;84(9):634-643
pubmed: 30007575
J Abnorm Psychol. 2013 May;122(2):506-12
pubmed: 23713504
Front Psychol. 2014 Dec 10;5:1431
pubmed: 25540631
Front Psychol. 2013 Feb 28;4:88
pubmed: 23450069
Psychol Med. 2015 Dec;45(16):3527-37
pubmed: 26315020
J Neurosci. 2010 Mar 10;30(10):3777-81
pubmed: 20220012
Compr Psychiatry. 2016 Apr;66:67-70
pubmed: 26995238
Psychopharmacology (Berl). 1986;89(2):177-82
pubmed: 3088634
Behav Brain Sci. 2003 Feb;26(1):65-82; discussion 82-137
pubmed: 14598440
Perception. 1987;16(6):693-709
pubmed: 3331424
Comput Psychiatr. 2017 Dec 01;1:102-131
pubmed: 30090855
Trends Cogn Sci. 2019 Feb;23(2):114-127
pubmed: 30583945
Cogn Neuropsychiatry. 2003 Feb;8(1):57-71
pubmed: 16571550
J Abnorm Psychol. 1998 Feb;107(1):49-62
pubmed: 9505038
Rev Neurosci. 2010;21(4):289-98
pubmed: 21086761
Psychopathology. 1991;24(6):375-80
pubmed: 1685795