Universal screening for SARS-CoV-2 infection among pregnant women at Elmhurst Hospital Center, Queens, New York.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2020
Historique:
received: 17 05 2020
accepted: 17 08 2020
entrez: 10 12 2020
pubmed: 11 12 2020
medline: 5 1 2021
Statut: epublish

Résumé

Universal screening for SARS-CoV-2 infection on Labor and Delivery (L&D) units is a critical strategy to manage patient and health worker safety, especially in a vulnerable high-prevalence community. We describe the results of a SARS-CoV-2 universal screening program at the L&D Unit at Elmhurst Hospital in Queens, NY, a 545-bed public hospital serving a diverse, largely immigrant and low-income patient population and an epicenter of the global pandemic. We conducted a retrospective cross-sectional study. All pregnant women admitted to the L&D Unit of Elmhurst Hospital from March 29, 2020 to April 22, 2020 were included for analysis. The primary outcomes of the study were: (1) SARS-CoV-2 positivity among universally screened pregnant women, stratified by demographic characteristics, maternal comorbidities, and delivery outcomes; and (2) Symptomatic or asymptomatic presentation at the time of testing among SARS-CoV-2 positive women. A total of 126 obstetric patients were screened for SARS-CoV-2 between March 29 and April 22. Of these, 37% were positive. Of the women who tested positive, 72% were asymptomatic at the time of testing. Patients who tested positive for SARS-CoV-2 were more likely to be of Hispanic ethnicity (unadjusted difference 24.4 percentage points, CI 7.9, 41.0) and report their primary language as Spanish (unadjusted difference 32.9 percentage points, CI 15.8, 49.9) than patients who tested negative. In this retrospective cross-sectional study of data from a universal SARS-Cov-2 screening program implemented in the L&D unit of a safety-net hospital in Queens, New York, we found over one-third of pregnant women testing positive, the majority of those asymptomatic. The rationale for universal screening at the L&D Unit at Elmhurst Hospital was to ensure safety of patients and staff during an acute surge in SARS-Cov-2 infections through appropriate identification and isolation of pregnant women with positive test results. Women were roomed by their SARS-CoV-2 status given increasing space limitations. In addition, postpartum counseling was tailored to infection status. We quickly established discharge counseling and follow-up protocols tailored to their specific social needs. The experience at Elmhurst Hospital is instructive for other L&D units serving vulnerable populations and for pandemic preparedness.

Sections du résumé

BACKGROUND
Universal screening for SARS-CoV-2 infection on Labor and Delivery (L&D) units is a critical strategy to manage patient and health worker safety, especially in a vulnerable high-prevalence community. We describe the results of a SARS-CoV-2 universal screening program at the L&D Unit at Elmhurst Hospital in Queens, NY, a 545-bed public hospital serving a diverse, largely immigrant and low-income patient population and an epicenter of the global pandemic.
METHODS AND FINDINGS
We conducted a retrospective cross-sectional study. All pregnant women admitted to the L&D Unit of Elmhurst Hospital from March 29, 2020 to April 22, 2020 were included for analysis. The primary outcomes of the study were: (1) SARS-CoV-2 positivity among universally screened pregnant women, stratified by demographic characteristics, maternal comorbidities, and delivery outcomes; and (2) Symptomatic or asymptomatic presentation at the time of testing among SARS-CoV-2 positive women. A total of 126 obstetric patients were screened for SARS-CoV-2 between March 29 and April 22. Of these, 37% were positive. Of the women who tested positive, 72% were asymptomatic at the time of testing. Patients who tested positive for SARS-CoV-2 were more likely to be of Hispanic ethnicity (unadjusted difference 24.4 percentage points, CI 7.9, 41.0) and report their primary language as Spanish (unadjusted difference 32.9 percentage points, CI 15.8, 49.9) than patients who tested negative.
CONCLUSIONS
In this retrospective cross-sectional study of data from a universal SARS-Cov-2 screening program implemented in the L&D unit of a safety-net hospital in Queens, New York, we found over one-third of pregnant women testing positive, the majority of those asymptomatic. The rationale for universal screening at the L&D Unit at Elmhurst Hospital was to ensure safety of patients and staff during an acute surge in SARS-Cov-2 infections through appropriate identification and isolation of pregnant women with positive test results. Women were roomed by their SARS-CoV-2 status given increasing space limitations. In addition, postpartum counseling was tailored to infection status. We quickly established discharge counseling and follow-up protocols tailored to their specific social needs. The experience at Elmhurst Hospital is instructive for other L&D units serving vulnerable populations and for pandemic preparedness.

Identifiants

pubmed: 33301498
doi: 10.1371/journal.pone.0238409
pii: PONE-D-20-14679
pmc: PMC7728244
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0238409

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Références

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pubmed: 32271722
N Engl J Med. 2020 May 28;382(22):2163-2164
pubmed: 32283004
Euro Surveill. 2020 Mar;25(10):
pubmed: 32183930

Auteurs

Sheela Maru (S)

Department of Health System Design and Global Health and the Arnhold Institute for Global Health, Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.
Department of Obstetrics, Gynecology and Reproductive Science at the Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.
New York City Health + Hospitals/Elmhurst, New York City, NY, United States of America.

Uday Patil (U)

New York City Health + Hospitals/Elmhurst, New York City, NY, United States of America.
Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.

Rachel Carroll-Bennett (R)

Department of Obstetrics, Gynecology and Reproductive Science at the Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.
New York City Health + Hospitals/Elmhurst, New York City, NY, United States of America.

Aaron Baum (A)

Department of Health System Design and Global Health and the Arnhold Institute for Global Health, Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.

Tracy Bohn-Hemmerdinger (T)

Department of Obstetrics, Gynecology and Reproductive Science at the Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.
New York City Health + Hospitals/Elmhurst, New York City, NY, United States of America.

Andrew Ditchik (A)

Department of Obstetrics, Gynecology and Reproductive Science at the Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.
New York City Health + Hospitals/Elmhurst, New York City, NY, United States of America.

Michael L Scanlon (ML)

Department of Health System Design and Global Health and the Arnhold Institute for Global Health, Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.

Parvathy Krishnan (P)

New York City Health + Hospitals/Elmhurst, New York City, NY, United States of America.
Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.

Kelly Bogaert (K)

Department of Obstetrics, Gynecology and Reproductive Science at the Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.
New York City Health + Hospitals/Elmhurst, New York City, NY, United States of America.

Carson Woodbury (C)

Department of Obstetrics, Gynecology and Reproductive Science at the Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.
New York City Health + Hospitals/Elmhurst, New York City, NY, United States of America.

Duncan Maru (D)

Department of Health System Design and Global Health and the Arnhold Institute for Global Health, Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.
New York City Health + Hospitals/Elmhurst, New York City, NY, United States of America.
Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.
Department of Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.

Lawrence Noble (L)

New York City Health + Hospitals/Elmhurst, New York City, NY, United States of America.
Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.

Randi Wasserman (R)

New York City Health + Hospitals/Elmhurst, New York City, NY, United States of America.
Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.

Barry Brown (B)

Department of Obstetrics, Gynecology and Reproductive Science at the Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.
New York City Health + Hospitals/Elmhurst, New York City, NY, United States of America.

Rachel Vreeman (R)

Department of Health System Design and Global Health and the Arnhold Institute for Global Health, Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.

Joseph Masci (J)

New York City Health + Hospitals/Elmhurst, New York City, NY, United States of America.
Department of Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America.

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Classifications MeSH