Incidence of Stroke and Ischemic Stroke Subtypes: A Community-Based Study in Brno, Czech Republic.


Journal

Cerebrovascular diseases (Basel, Switzerland)
ISSN: 1421-9786
Titre abrégé: Cerebrovasc Dis
Pays: Switzerland
ID NLM: 9100851

Informations de publication

Date de publication:
2021
Historique:
received: 07 07 2020
accepted: 11 09 2020
pubmed: 11 12 2020
medline: 6 8 2021
entrez: 10 12 2020
Statut: ppublish

Résumé

There are few contemporary epidemiological data on stroke for Central Europe. We performed a population-based study evaluating the incidence of stroke, stroke types, and ischemic stroke (IS) subtypes in Brno, the second biggest city in the Czech Republic (CR). Using the National Registry of Hospitalized Patients, and hospital databases, we identified all patients hospitalized with a stroke diagnosis in Brno hospitals in 2011. For Brno residents with validated stroke diagnosis, we calculated (a) the overall incidence of hospitalized stroke, (b) incidence rates for IS, subarachnoid hemorrhage (SAH) and intracerebral hemorrhage (ICH), and (c) incidence rates for IS subtypes. We calculated the average annual age- and sex-standardized incidence (European Standard Population and World Health Organization), to compare our results with other studies. The overall crude incidence of stroke in Brno was 213/100,000 population. The incidence of stroke for stroke types were as follows: SAH, 6.9; ICH, 26.4; and IS, 180 cases per 100,000 population, respectively. The WHO-standardized annual stroke incidence was 107 for all strokes and 88 for IS, 14.4 for ICH, and 5 for SAH. For IS subtypes, the WHO-standardized incidence was large artery atherosclerosis 25.8, cardioembolism 27.8, lacunar 21.6, other determined etiology 6.2, and undetermined etiology 6.5 cases per 100,000 population. The stroke incidence is lower than that previously reported for the CR and Eastern Europe probably reflecting socioeconomic changes in post-communistic countries in the region. These findings could contribute to stroke prevention strategies and influence health policies.

Sections du résumé

BACKGROUND
There are few contemporary epidemiological data on stroke for Central Europe. We performed a population-based study evaluating the incidence of stroke, stroke types, and ischemic stroke (IS) subtypes in Brno, the second biggest city in the Czech Republic (CR).
METHODS
Using the National Registry of Hospitalized Patients, and hospital databases, we identified all patients hospitalized with a stroke diagnosis in Brno hospitals in 2011. For Brno residents with validated stroke diagnosis, we calculated (a) the overall incidence of hospitalized stroke, (b) incidence rates for IS, subarachnoid hemorrhage (SAH) and intracerebral hemorrhage (ICH), and (c) incidence rates for IS subtypes. We calculated the average annual age- and sex-standardized incidence (European Standard Population and World Health Organization), to compare our results with other studies.
RESULTS
The overall crude incidence of stroke in Brno was 213/100,000 population. The incidence of stroke for stroke types were as follows: SAH, 6.9; ICH, 26.4; and IS, 180 cases per 100,000 population, respectively. The WHO-standardized annual stroke incidence was 107 for all strokes and 88 for IS, 14.4 for ICH, and 5 for SAH. For IS subtypes, the WHO-standardized incidence was large artery atherosclerosis 25.8, cardioembolism 27.8, lacunar 21.6, other determined etiology 6.2, and undetermined etiology 6.5 cases per 100,000 population.
CONCLUSIONS
The stroke incidence is lower than that previously reported for the CR and Eastern Europe probably reflecting socioeconomic changes in post-communistic countries in the region. These findings could contribute to stroke prevention strategies and influence health policies.

Identifiants

pubmed: 33302276
pii: 000512180
doi: 10.1159/000512180
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

54-61

Informations de copyright

© 2020 The Author(s) Published by S. Karger AG, Basel.

Auteurs

Petra Sedova (P)

Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA.
International Clinical Research Center, St. Anne's University Hospital, Brno, Czechia.
Department of Internal Medicine, Haematology and Oncology, University Hospital Brno, and Faculty of Medicine, Masaryk University, Brno, Czechia.

Robert D Brown (RD)

Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA.

Miroslav Zvolsky (M)

Institute of Health Information and Statistics of the Czech Republic, Prague, Czechia.

Silvia Belaskova (S)

International Clinical Research Center, St. Anne's University Hospital, Brno, Czechia.

Michaela Volna (M)

International Clinical Research Center, St. Anne's University Hospital, Brno, Czechia.

Jana Baluchova (J)

International Clinical Research Center, St. Anne's University Hospital, Brno, Czechia.

Josef Bednarik (J)

Department of Neurology, University Hospital Brno, and Faculty of Medicine, Masaryk University, Brno, Czechia.

Robert Mikulik (R)

International Clinical Research Center, St. Anne's University Hospital, Brno, Czechia, mikulik@hotmail.com.
Department of Neurology, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, Brno, Czechia, mikulik@hotmail.com.

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