The effect of cannabidiol on sevoflurane minimum alveolar concentration reduction produced by morphine in rats.

Analgesics, Opioid / pharmacology Anesthetics, Inhalation Animals Cannabidiol / pharmacology Male Morphine / pharmacology Rats Rats, Wistar Sevoflurane
cannabidiol minimum alveolar concentration (MAC) morphine rat sevoflurane

Journal

Veterinary anaesthesia and analgesia
ISSN: 1467-2995
Titre abrégé: Vet Anaesth Analg
Pays: United States
ID NLM: 100956422

Informations de publication

Date de publication:
Jan 2021
Historique:
received: 04 04 2019
revised: 09 01 2020
accepted: 05 04 2020
pubmed: 12 12 2020
medline: 11 11 2021
entrez: 11 12 2020
Statut: ppublish

Résumé

To investigate the effect of cannabidiol (CBD) on sevoflurane minimum alveolar concentration (MAC Randomized, blinded trial. A total of 75 male Wistar Han rats weighing 276 ± 23 g (mean and standard deviation), aged 3 months. Cannabidiol (CBD) was prepared in an ethanol-solutol-saline vehicle. Animals were randomly divided into 15 groups and given an intraperitoneal bolus of 1, 3, 5, 6.5, 7.5 or 10 mg kg MAC

Identifiants

DOI: 10.1016/j.vaa.2020.04.017 PMID: 33303398
pubmed: 33303398
pii: S1467-2987(20)30224-5
doi: 10.1016/j.vaa.2020.04.017
pii:
doi:

Substances chimiques

Analgesics, Opioid 0
Anesthetics, Inhalation 0
Cannabidiol 19GBJ60SN5
Sevoflurane 38LVP0K73A
Morphine 76I7G6D29C

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

74-81

Informations de copyright

Copyright © 2020 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia. Published by Elsevier Ltd. All rights reserved.

Auteurs

Cristina Orden (C)

Medical and Surgical Research Unit, Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain. Electronic address: cristinaordenq@gmail.com.

Martín Santos (M)

Medical and Surgical Research Unit, Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain.

María Ceprian (M)

Medical and Surgical Research Unit, Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain; Department of Biochemistry and Molecular Biology III, CIBERNED, IRICYS, School of Medicine, Universidad Complutense de Madrid, Spain.

Francisco J Tendillo (FJ)

Medical and Surgical Research Unit, Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain.

Articles similaires

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Meal Timing and Anthropometric and Metabolic Outcomes: A Systematic Review and Meta-Analysis.

Hiu Yee Liu, Ashley A Eso, Nathan Cook et al.
1.00
Humans Meals Time Factors Female Adult

Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents du système nerveux central › Dépresseurs du système nerveux central › Stupéfiants › Analgésiques morphiniques › The effect of cannabidiol on sevoflurane...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents du système nerveux central › Dépresseurs du système nerveux central › Anesthésiques › Anesthésiques généraux › Anesthésiques par inhalation › The effect of cannabidiol on sevoflurane...
questionsmedicales.fr › Eucaryotes › Animaux › The effect of cannabidiol on sevoflurane...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Cannabinoïdes › Cannabidiol › The effect of cannabidiol on sevoflurane...
questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Phénanthrènes › Morphinanes › Dérivés de la morphine › Morphine › The effect of cannabidiol on sevoflurane...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › The effect of cannabidiol on sevoflurane...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Rat Wistar › The effect of cannabidiol on sevoflurane...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures halogénés › Hydrocarbures fluorés › Sévoflurane › The effect of cannabidiol on sevoflurane...