Haemolytic anaemia: a consequence of COVID-19.


Journal

BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291

Informations de publication

Date de publication:
10 Dec 2020
Historique:
entrez: 11 12 2020
pubmed: 12 12 2020
medline: 17 12 2020
Statut: epublish

Résumé

A man in his early 50s presented with jaundice, mild shortness of breath on exertion and dark urine. He had had coryzal symptoms 2 weeks prior to admission. Medical history included obstructive sleep apnoea and hypertension. His initial blood tests showed a mild hyperbilirubinaemia and acute kidney injury stage 1. Chest X-ray and CT pulmonary angiogram were negative for features suggestive of COVID-19. He later developed a drop in haemoglobin and repeat bloods showed markedly raised lactate dehydrogenase and positive direct antiglobulin test. These results were felt to be consistent with a haemolytic anaemia. A nasopharyngeal swab came back positive for COVID-19. We suspect the cause of his symptoms was an autoimmune haemolytic anaemia secondary to COVID-19 which has recently been described in European cohorts.

Identifiants

pubmed: 33303503
pii: 13/12/e238118
doi: 10.1136/bcr-2020-238118
pmc: PMC10577752
pii:
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

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pubmed: 32369626
JAMA. 2020 Apr 28;323(16):1612-1614
pubmed: 32191259
J Clin Virol. 2020 Sep;130:104575
pubmed: 32805631
Br J Haematol. 2020 Jul;190(1):29-31
pubmed: 32374906
Br J Haematol. 2016 Jan;172(1):144-6
pubmed: 25941063
Kidney Int. 2020 Jul;98(1):219-227
pubmed: 32327202
JAMA Intern Med. 2020 Sep 1;180(9):1156-1163
pubmed: 32356867

Auteurs

Memoona Jawed (M)

Queen's Medical Centre, Nottingham University Hospital NHS Trust, Nottingham, UK memoona.jawed@nuh.nhs.uk.
Acute Medicine, Queen's Medical Centre, Nottingham University Hospital NHS Trust, Nottingham, UK.

Elizabeth Hart (E)

Acute Medicine, Nottingham University Hospitals NHS Trust, Nottingham, UK.

Malik Saeed (M)

Haematology, Nottingham University Hospitals NHS Trust, Nottingham, UK.

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