A case of laryngopharyngeal reflux-associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay.
chronic cough
laryngopharyngeal reflux
mosapride
proton‐pump inhibitor
silent aspiration
Journal
Journal of general and family medicine
ISSN: 2189-7948
Titre abrégé: J Gen Fam Med
Pays: Japan
ID NLM: 101689875
Informations de publication
Date de publication:
Nov 2020
Nov 2020
Historique:
received:
27
02
2020
revised:
01
05
2020
accepted:
14
05
2020
entrez:
11
12
2020
pubmed:
12
12
2020
medline:
12
12
2020
Statut:
epublish
Résumé
A 62-year-old woman presented with a dry cough lasting 18 months. She had previously been examined by multiple doctors, but no abnormalities were observed. Several medications such as rabeprazole and inhaled corticosteroids were administered as test treatments without any improvement. Therefore, the possibility of biological disease, including acid reflux, had been mistakenly ruled out. We examined the sputum gram stain. The result showed phagocyted normal bacterial flora, suggesting aspiration. Laryngoscopy revealed edema of the arytenoid cartilage. The patient was finally diagnosed with laryngopharyngeal reflux and silent aspiration. This case suggested that the ineffectiveness of proton-pump inhibitors cannot always exclude the presence of reflux disease and the usefulness of gram stain examination to detect silent aspiration.
Identifiants
pubmed: 33304721
doi: 10.1002/jgf2.348
pii: JGF2348
pmc: PMC7689238
doi:
Types de publication
Case Reports
Langues
eng
Pagination
258-260Informations de copyright
© 2020 The Authors. Journal of General and Family Medicine published by John Wiley & Sons Australia, Ltd on behalf of Japan Primary Care Association.
Déclaration de conflit d'intérêts
The authors have stated explicitly that there are no conflicts of interest in connection with this article.
Références
Cough. 2007 Jan 08;3:1
pubmed: 17210085
BMJ. 2014 Oct 09;349:g5813
pubmed: 25300569
World J Gastroenterol. 2013 Aug 21;19(31):5118-24
pubmed: 23964146
Otolaryngol Head Neck Surg. 2002 Jul;127(1):32-5
pubmed: 12161727
Otolaryngol Head Neck Surg. 2008 Sep;139(3):414-20
pubmed: 18722223
Gastroenterology. 2010 Sep;139(3):754-62
pubmed: 20600028
Eur Arch Otorhinolaryngol. 2013 Mar;270(4):1385-90
pubmed: 23292040
Otolaryngol Head Neck Surg. 2016 Dec;155(6):923-935
pubmed: 27554511
Ann Otol Rhinol Laryngol. 2003 Jun;112(6):481-91
pubmed: 12834114
Scand J Gastroenterol. 2010 May;45(5):533-9
pubmed: 20180645
Gastroenterology. 2008 Oct;135(4):1392-1413, 1413.e1-5
pubmed: 18801365
Am J Med. 2000 Mar 6;108 Suppl 4a:27S-37S
pubmed: 10718448