Transcranial Ultrasound Innovations Ready for Broad Clinical Application.
brain therapy
neuropsychiatric disease
ultrasound
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
ISSN: 2198-3844
Titre abrégé: Adv Sci (Weinh)
Pays: Germany
ID NLM: 101664569
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
29
05
2020
revised:
24
08
2020
entrez:
11
12
2020
pubmed:
12
12
2020
medline:
12
12
2020
Statut:
epublish
Résumé
Brain diseases are one of the most important problems in our rapidly ageing society. Currently, there are not many effective medications and surgical options are limited due to invasiveness and non-invasive brain stimulation techniques cannot be well targeted and cannot access deep brain areas. A novel therapy is transcranial ultrasound which allows a variety of treatments without opening of the skull. Recent technological developments generated three revolutionary options including 1) targeted non-invasive surgery, 2) highly targeted drug, antibody, or gene therapy via local opening of the blood-brain barrier, and 3) highly targeted brain stimulation to improve pathological brain functions. This progress report summarizes the current state of the art for clinical application and the results of recent patient investigations.
Identifiants
pubmed: 33304757
doi: 10.1002/advs.202002026
pii: ADVS2068
pmc: PMC7709976
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
2002026Informations de copyright
© 2020 The Authors. Published by Wiley‐VCH GmbH.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
Sci Transl Med. 2016 Jun 15;8(343):343re2
pubmed: 27306666
Adv Sci (Weinh). 2019 Dec 23;7(3):1902583
pubmed: 32042569
Sci Rep. 2016 Aug 11;6:31201
pubmed: 27510760
J Psychiatry Neurosci. 2018 Aug;43(5):327-337
pubmed: 30125241
J Neurosurg. 2018 May 1;:1-10
pubmed: 29799340
Neurosurgery. 2019 May 1;84(5):1138-1148
pubmed: 29905844
Sci Rep. 2015 Mar 04;5:8743
pubmed: 25735418
Stereotact Funct Neurosurg. 2020;98(3):182-186
pubmed: 32224617
Ann Neurol. 2019 Dec;86(6):975-980
pubmed: 31525269
J Neurosurg. 2015 Jan;122(1):152-61
pubmed: 25380106
J Ther Ultrasound. 2014 Oct 16;2:17
pubmed: 25671132
Oper Neurosurg (Hagerstown). 2020 Jul 1;19(1):9-18
pubmed: 31853548
Proc Natl Acad Sci U S A. 2020 Apr 28;117(17):9180-9182
pubmed: 32284421
Nat Commun. 2019 Sep 26;10(1):4373
pubmed: 31558719
Neurosurgery. 2010 Feb;66(2):323-32; discussion 332
pubmed: 20087132
Biol Psychiatry. 2018 Jan 1;83(1):e17-e18
pubmed: 28601192
Neurosurgery. 2020 Jul 1;87(1):1-10
pubmed: 31745558
Neurology. 2019 Dec 10;93(24):e2284-e2293
pubmed: 31748250
Mov Disord. 2019 May;34(5):727-734
pubmed: 30759322
JAMA. 2020 Feb 11;323(6):499
pubmed: 32044919
Elife. 2019 Feb 12;8:
pubmed: 30747105
N Engl J Med. 2016 Aug 25;375(8):730-9
pubmed: 27557301
NeuroRehabilitation. 2014 Jan 1;35(2):235-44
pubmed: 24990026
Proc Natl Acad Sci U S A. 2017 Jan 3;114(1):E75-E84
pubmed: 27994152
Cereb Cortex. 2020 Jun 30;30(8):4597-4606
pubmed: 32248223
Ultrasound Med Biol. 2004 Jul;30(7):979-89
pubmed: 15313330
Sci Rep. 2016 Sep 23;6:34026
pubmed: 27658372
Sci Rep. 2017 Nov 10;7(1):15321
pubmed: 29127399
Brain Stimul. 2016 Nov - Dec;9(6):940-941
pubmed: 27567470
Brain Stimul. 2019 Jul - Aug;12(4):901-910
pubmed: 30880027
Front Hum Neurosci. 2020 Feb 28;14:52
pubmed: 32184714
Clin Cancer Res. 2019 Jul 1;25(13):3793-3801
pubmed: 30890548
Nat Commun. 2018 Jul 25;9(1):2336
pubmed: 30046032
Cereb Cortex. 2019 Apr 1;29(4):1430-1438
pubmed: 30873554
Stroke. 2005 Jul;36(7):1441-6
pubmed: 15947262
J Neurosurg. 2018 Sep 21;131(2):384-386
pubmed: 30239322
Neuroimage. 2019 Oct 15;200:275-280
pubmed: 31254646
IEEE Trans Ultrason Ferroelectr Freq Control. 2016 Feb 18;63(5):671-682
pubmed: 26890732
Brain Stimul. 2019 Nov - Dec;12(6):1367-1380
pubmed: 31401074
Mov Disord. 2019 Jan;34(1):148-149
pubmed: 30485534
Neurosurg Focus. 2012 Jan;32(1):E1
pubmed: 22208894
Brain Stimul. 2013 May;6(3):409-15
pubmed: 22664271
Alzheimers Dement (N Y). 2019 Aug 08;5:374-381
pubmed: 31440580
Mult Scler. 2020 Jun;26(7):855-858
pubmed: 31617444
Handb Clin Neurol. 2019;163:73-92
pubmed: 31590749
J Neurooncol. 2020 Feb 28;:
pubmed: 32112296
Sci Rep. 2020 Mar 27;10(1):5573
pubmed: 32221350
Neuropharmacology. 2017 Jul 1;120:20-37
pubmed: 26907805
BMC Neurosci. 2016 Oct 26;17(1):68
pubmed: 27784293
Eur J Nucl Med Mol Imaging. 2020 Feb;47(2):425-436
pubmed: 31705173
J Korean Neurosurg Soc. 2019 Jan;62(1):10-26
pubmed: 30630292
Sci Transl Med. 2015 Mar 11;7(278):278ra33
pubmed: 25761889
Mov Disord. 2018 Oct;33(10):1647-1650
pubmed: 30288794
Lancet Neurol. 2013 May;12(5):462-8
pubmed: 23523144
Sci Rep. 2019 Jan 23;9(1):321
pubmed: 30674905
J Control Release. 2019 Sep 10;309:25-36
pubmed: 31326464