Effect of enhanced recovery after surgery protocol on recovery after open hepatectomy: a randomized clinical trial.
Enhanced recovery after surgery
Hepatectomy
Perioperative treatments
Randomized controlled trial
Journal
Annals of surgical treatment and research
ISSN: 2288-6575
Titre abrégé: Ann Surg Treat Res
Pays: Korea (South)
ID NLM: 101622895
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
14
05
2020
revised:
16
07
2020
accepted:
21
08
2020
entrez:
11
12
2020
pubmed:
12
12
2020
medline:
12
12
2020
Statut:
ppublish
Résumé
Enhanced recovery after surgery (ERAS) is beneficial to patients undergoing digestive surgery. However, its efficacy in patients undergoing open hepatectomy remains unclear. Consecutive patients scheduled for open hepatectomy were randomly assigned to undergo either ERAS or conventional postoperative management. The primary endpoint was the amount of time that elapsed before patients were considered medically fit for discharge (MFD) and length of hospital stay (LOHS). Secondary endpoints included morbidity, mortality, the time to first flatus, defecation, first walk, and freedom from infusion. Perioperative serum nutritional markers, insulin resistance, respiratory quotient (RQ), and resting energy expenditure (REE) were also assessed. Between August 2014 and March 2017, 57 patients were randomized into 2 groups; ERAS group (n = 29) and conventional management (n = 28). The median MFD was not significantly different between the ERAS and conventional management groups (6.5 This trial did not demonstrate greater efficacy of the ERAS protocol following open hepatectomy in terms of the MFD and LOHS. However, the ERAS protocol was associated with better recovery from postoperative gastrointestinal paresis, suggesting that it is useful for patients undergoing open hepatectomy.
Identifiants
pubmed: 33304859
doi: 10.4174/astr.2020.99.6.320
pmc: PMC7704272
doi:
Types de publication
Journal Article
Langues
eng
Pagination
320-328Informations de copyright
Copyright © 2020, the Korean Surgical Society.
Déclaration de conflit d'intérêts
Conflict of Interest: No potential conflict of interest relevant to this article was reported.
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