Self-Association in EO-BO-EO Triblock Copolymers as a Nanocarrier Template for Sustainable Release of Anticancer Drugs.
Journal
The journal of physical chemistry. B
ISSN: 1520-5207
Titre abrégé: J Phys Chem B
Pays: United States
ID NLM: 101157530
Informations de publication
Date de publication:
24 12 2020
24 12 2020
Historique:
pubmed:
12
12
2020
medline:
15
5
2021
entrez:
11
12
2020
Statut:
ppublish
Résumé
Ethylene oxide (EO)-butylene oxide (BO)-ethylene oxide (EO)-based triblock copolymers with varying hydrophilic-hydrophobic ratios in arrangement, generally referred to as EBE, were scrutinized in an aqueous environment. Various self-associative (micellization) physicochemical properties of these EBEs were examined at different temperatures unified with a quantum chemical study. The salting-out effect on 5%w/v EBE was examined by observing their aqueous solution behavior where the clear transparent solution/turbidity suggested the probable presence of spherical or ellipsoidal micelles, which was confirmed from the scattering outline. The hydrodynamic radius (
Identifiants
pubmed: 33305575
doi: 10.1021/acs.jpcb.0c09386
doi:
Substances chimiques
Alkenes
0
Antineoplastic Agents
0
Micelles
0
Polymers
0
butylene
25167-67-3
Ethylene Oxide
JJH7GNN18P
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM