Epidemiology, longitudinal treatment patterns and outcomes of chronic lymphocytic leukemia in Israel.


Journal

Leukemia & lymphoma
ISSN: 1029-2403
Titre abrégé: Leuk Lymphoma
Pays: United States
ID NLM: 9007422

Informations de publication

Date de publication:
05 2021
Historique:
pubmed: 12 12 2020
medline: 20 5 2021
entrez: 11 12 2020
Statut: ppublish

Résumé

This study aims to describe chronic lymphocytic leukemia (CLL) epidemiology, treatment patterns and outcomes in a 2.3-million-member healthcare provider database (Maccabi Healthcare Services, Israel). Newly-diagnosed CLL patients (1999-2017) were followed through 31/3/2018. A total of 1857 newly-diagnosed CLL patients were included. Annual incidence was 5.82 per 100,000 population. Median overall survival (OS) was 12.7 (95%CI: 11.8-13.5) years since diagnosis. Approximately 1/3 initiated treatment within 5 y. A statistical trend (

Identifiants

pubmed: 33305641
doi: 10.1080/10428194.2020.1858293
doi:

Substances chimiques

Rituximab 4F4X42SYQ6
Cyclophosphamide 8N3DW7272P
Bendamustine Hydrochloride 981Y8SX18M
Vidarabine FA2DM6879K

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1136-1145

Auteurs

Clara Weil (C)

Maccabi Institute for Research and Innovation (Maccabitech), Maccabi Healthcare Services, Tel Aviv, Israel.

Gabriel Chodick (G)

Maccabi Institute for Research and Innovation (Maccabitech), Maccabi Healthcare Services, Tel Aviv, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Varda Shalev (V)

Maccabi Institute for Research and Innovation (Maccabitech), Maccabi Healthcare Services, Tel Aviv, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Inna Kan (I)

AbbVie Inc, Hod Hasharon, Israel.

Ran Afik (R)

AbbVie Inc, Hod Hasharon, Israel.

Raanan Cohen (R)

AbbVie Inc, Hod Hasharon, Israel.

Kavita Sail (K)

AbbVie Inc, North Chicago, IL, USA.

Yair Herishanu (Y)

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Department of Hematology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.

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Classifications MeSH