Male infertility.


Journal

Lancet (London, England)
ISSN: 1474-547X
Titre abrégé: Lancet
Pays: England
ID NLM: 2985213R

Informations de publication

Date de publication:
23 01 2021
Historique:
received: 18 02 2020
revised: 13 08 2020
accepted: 19 08 2020
pubmed: 15 12 2020
medline: 6 3 2021
entrez: 14 12 2020
Statut: ppublish

Résumé

It is estimated that infertility affects 8-12% of couples globally, with a male factor being a primary or contributing cause in approximately 50% of couples. Causes of male subfertility vary highly, but can be related to congenital, acquired, or idiopathic factors that impair spermatogenesis. Many health conditions can affect male fertility, which underscores the need for a thorough evaluation of patients to identify treatable or reversible lifestyle factors or medical conditions. Although semen analysis remains the cornerstone for evaluating male infertility, advanced diagnostic tests to investigate sperm quality and function have been developed to improve diagnosis and management. The use of assisted reproductive techniques has also substantially improved the ability of couples with infertility to have biological children. This Seminar aims to provide a comprehensive overview of the assessment and management of men with infertility, along with current controversies and future endeavours.

Identifiants

pubmed: 33308486
pii: S0140-6736(20)32667-2
doi: 10.1016/S0140-6736(20)32667-2
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

319-333

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Auteurs

Ashok Agarwal (A)

American Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH, USA. Electronic address: agarwaa@ccf.org.

Saradha Baskaran (S)

American Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH, USA.

Neel Parekh (N)

Department of Urology, Cleveland Clinic, Cleveland, OH, USA.

Chak-Lam Cho (CL)

SH Ho Urology Center, Department of Surgery, Chinese University of Hong Kong, Hong Kong.

Ralf Henkel (R)

American Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH, USA; Department of Medical Bioscience, University of Western Cape, Bellville, South Africa; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.

Sarah Vij (S)

Department of Urology, Cleveland Clinic, Cleveland, OH, USA.

Mohamed Arafa (M)

Male Infertility Unit, Urology Department, Hamad Medical Corporation, Doha, Qatar; Andrology Department, Cairo University, Cairo, Egypt.

Manesh Kumar Panner Selvam (MK)

American Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH, USA.

Rupin Shah (R)

Department of Urology, Lilavati Hospital and Research Center, Mumbai, India.

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Classifications MeSH