The impact of bariatric surgery on nonalcoholic fatty liver disease as measured using non-invasive tests.
Adult
Aged
Bariatric Surgery
Elasticity Imaging Techniques
Feasibility Studies
Female
Humans
Liver
/ diagnostic imaging
Liver Cirrhosis
/ blood
Liver Function Tests
Male
Middle Aged
Non-alcoholic Fatty Liver Disease
/ blood
Obesity, Morbid
/ complications
Prospective Studies
Severity of Illness Index
Treatment Outcome
Weight Loss
Young Adult
Bariatric surgery
Non-invasive tests
Nonalcoholic fatty liver disease
Nonalcoholic-steatohepatitis
Steatosis
Journal
American journal of surgery
ISSN: 1879-1883
Titre abrégé: Am J Surg
Pays: United States
ID NLM: 0370473
Informations de publication
Date de publication:
07 2021
07 2021
Historique:
received:
31
05
2020
revised:
28
08
2020
accepted:
22
11
2020
pubmed:
15
12
2020
medline:
4
8
2021
entrez:
14
12
2020
Statut:
ppublish
Résumé
Nonalcoholic fatty liver disease (NAFLD) is common in bariatric surgery candidates. We evaluated the effect of sleeve gastrectomy (SG) on NAFLD using validated non-invasive measures. Patients with morbid obesity and NAFLD, planned for SG, were evaluated before and after surgery. Data collected included anthropometrics, biochemistry, adiponectin, SteatoTest™, NashTest™, FibroTest™, OWLiver® test and real-time ShearWave™ elastography (SWE). Twenty-six subjects were included in the study, mean age 44.1 ± 4.8 years, 69.2% males. One year following SG, body mass index decreased significantly from 41.7 ± 4.8 kg/m Steatosis and steatohepatitis are significantly improved by SG as measured by non-invasive measures.
Sections du résumé
BACKGROUND
Nonalcoholic fatty liver disease (NAFLD) is common in bariatric surgery candidates. We evaluated the effect of sleeve gastrectomy (SG) on NAFLD using validated non-invasive measures.
METHODS
Patients with morbid obesity and NAFLD, planned for SG, were evaluated before and after surgery. Data collected included anthropometrics, biochemistry, adiponectin, SteatoTest™, NashTest™, FibroTest™, OWLiver® test and real-time ShearWave™ elastography (SWE).
RESULTS
Twenty-six subjects were included in the study, mean age 44.1 ± 4.8 years, 69.2% males. One year following SG, body mass index decreased significantly from 41.7 ± 4.8 kg/m
CONCLUSION
Steatosis and steatohepatitis are significantly improved by SG as measured by non-invasive measures.
Identifiants
pubmed: 33309037
pii: S0002-9610(20)30767-4
doi: 10.1016/j.amjsurg.2020.11.045
pii:
doi:
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
214-219Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest All authors declare that they have no conflict of interest.