[Thymoma and squamous thymic carcinoma diagnosis; experience from the RYTHMIC network].
Diagnostic des thymomes et carcinomes thymiques malpighiens ; expérience du réseau RYTHMIC.
Carcinome thymique
Immunohistochemistry
Immunohistochimie
RYTHMIC
Stade
Stage
Thymic carcinoma
Thymoma
Thymome
Journal
Annales de pathologie
ISSN: 0242-6498
Titre abrégé: Ann Pathol
Pays: France
ID NLM: 8106337
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
received:
18
07
2020
revised:
10
10
2020
accepted:
11
11
2020
pubmed:
15
12
2020
medline:
16
10
2021
entrez:
14
12
2020
Statut:
ppublish
Résumé
The RYTHMIC network, supported by the French National Cancer Institute is dedicated to the management of patients with thymic epithelial tumors through regional and national multidisciplinary tumor boards. Tumor board decisions are based on the initial pathology diagnoses. However, following clinical inclusion in the network, a central pathology review is organized, implicating a panel of pathologists, for histotype and stage classification, which is different from a classical second opinion from pathologist to pathologist for a difficult case. Thanks to the participation of all French pathologists, more than 1000 cases have been reviewed by the panel. The aim of this review is to share with the French pathology community, the experience of the group. It underlines the importance of macroscopy and surgeon-pathologist involvement to allow a good central review, the main histopathological and immunophenotypical patterns of the most frequent thymomas and thymic carcinoma types, the differential diagnoses, as well as the difficulties for the panel to reproducibly assess on slides, stage, for some cases.
Identifiants
pubmed: 33309329
pii: S0242-6498(20)30268-6
doi: 10.1016/j.annpat.2020.11.002
pii:
doi:
Types de publication
Journal Article
Review
Langues
fre
Sous-ensembles de citation
IM
Pagination
154-165Informations de copyright
Copyright © 2020 Elsevier Masson SAS. All rights reserved.