Impact of Radiation Therapy on Pain Relief of Cancer Patients Affected by on Malignant Psoas Syndrome: 26 Years of Experience.
Malignant psoas syndrome
pain
radiotherapy
Journal
Indian journal of palliative care
ISSN: 0973-1075
Titre abrégé: Indian J Palliat Care
Pays: United States
ID NLM: 101261221
Informations de publication
Date de publication:
Historique:
received:
23
11
2019
accepted:
26
03
2020
entrez:
14
12
2020
pubmed:
15
12
2020
medline:
15
12
2020
Statut:
ppublish
Résumé
The malignant psoas syndrome (MPS) is a rare and complex cancer-related clinical entity, with a significant impact on cancer patients' quality of life. The literature describing malignant infiltration of the psoas muscle as well as its management is limited. The primary endpoint of the study was the assessment of pain relief in symptomatic terminal-stage MPS patients. Patients underwent hypofractionated (two- or three-dimensional conformal) radiotherapy as palliative treatment. A dose of 42.5 Gy in 17 daily fractions (2.5 Gy/fraction) was prescribed. Pain response was measured before 3 and 6 months after radiation delivery. Between May 1992 and April 2019, eight patients were treated. The median age was 75 years (range: 59-87 years). All patients had distant metastatic disease at the time of treatment. We found a significant pain relief (median duration of response of 105 days) and an improvement in health-related quality of life. Radiotherapy had a favorable outcome and can be considered an effective analgesic treatment in case of painful MPS.
Identifiants
pubmed: 33311878
doi: 10.4103/IJPC.IJPC_205_19
pii: IJPC-26-348
pmc: PMC7725172
doi:
Types de publication
Journal Article
Langues
eng
Pagination
348-351Informations de copyright
Copyright: © 2020 Indian Journal of Palliative Care.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
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