The effects of shock wave therapy applied on hypertrophic burn scars: a randomised controlled trial.
Extracorporeal shock wave therapy
elasticity
hypertrophic scar
low-energy shock waves
mechanotransduction
non-invasive treatment
scar management
Journal
Scars, burns & healing
ISSN: 2059-5131
Titre abrégé: Scars Burn Heal
Pays: United States
ID NLM: 101718377
Informations de publication
Date de publication:
Historique:
entrez:
14
12
2020
pubmed:
15
12
2020
medline:
15
12
2020
Statut:
epublish
Résumé
A wide variety of non-invasive treatments has been proposed for the management of hypertrophic burn scars. Unfortunately, the reported efficacy has not been consistent, and especially in the first three months after wound closure, fragility of the scarred skin limits the treatment options. Extracorporeal shock wave therapy (ESWT) is a new non-invasive type of mechanotherapy to treat wounds and scars. The aim of the present study was to examine the objective and subjective scar-related effects of ESWT on burn scars in the early remodelling phase. Evaluations included the Patient and Observer Scar Assessment Scale (POSAS) for scar quality, tri-stimulus colorimetry for redness, tewametry for trans-epidermal water loss (TEWL) and cutometry for elasticity. Patients were randomly assigned to one of two groups, the low-energy intervention group or the placebo control group, and were tested at baseline, after one, three and six months. All patients were treated with pressure garments, silicone and moisturisers. Both groups received the ESWT treatment (real or placebo) once a week for 10 weeks. Results for 20 patients in each group after six months are presented. The objective assessments showed a statistically significant effect of ESWT compared with placebo on elasticity ( ESWT can give added value to the non-invasive treatment of hypertrophic scars, more specifically to improve elasticity when the treatment was already started in the first three months after wound closure. Pathological scarring is a common problem after a burn injury. A wide variety of non-invasive treatments has been proposed for the management of these scars. Unfortunately, the reported efficacy of these interventions has not been consistent, and especially in the first three months after wound closure, fragility of the scarred skin limits the treatment options. Extracorporeal shock wave therapy (ESWT) is a relatively new non-invasive therapy to treat both wounds and scars. The aim of the present study was to examine the scar-related effects of ESWT on burn scars in the early phase of healing.The scars were subjectively assessed for scar quality by the patient and an observer using the Patient and Observer Scar Assessment Scale (POSAS). Objective assessments included measurements to assess redness, water loss and elasticity. Forty patients were randomly assigned to one of two groups, the low-energy intervention group or the placebo control group (the device simulated the sound of an ESWT treatment but no real shocks were applied), and were tested at four timepoints up to six months. All patients were treated with pressure garments, silicone and moisturisers. Both groups received the ESWT treatment (real or placebo) once a week for 10 weeks.The objective assessments showed a significant improvement of elasticity in the intervention group when compared with placebo but revealed no significant effects on redness and water loss. Results of the clinical assessments showed no differences between the groups for the POSAS Patient and Observer scores.ESWT can give added value to the non-invasive treatment of pathological scars more specifically to improve elasticity in the early phase of healing.
Identifiants
pubmed: 33312712
doi: 10.1177/2059513120975624
pii: 10.1177_2059513120975624
pmc: PMC7716075
doi:
Types de publication
Journal Article
Langues
eng
Pagination
2059513120975624Informations de copyright
© The Author(s) 2020.
Déclaration de conflit d'intérêts
Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Références
Wound Repair Regen. 2012 Jul-Aug;20(4):456-65
pubmed: 22642362
Med Sci Monit. 2016 Mar 20;22:914-21
pubmed: 26994898
Burns. 2012 Aug;38(5):638-44
pubmed: 22335885
Clin Rehabil. 2015 May;29(5):439-46
pubmed: 25187393
Burns. 2019 Aug;45(5):1094-1101
pubmed: 30827852
Burns. 2004 Mar;30(2):109-14
pubmed: 15019116
Dermatol Ther (Heidelb). 2013 Dec;3(2):143-55
pubmed: 24297647
Burns. 2013 May;39(3):420-8
pubmed: 23000371
Acta Orthop. 2009 Oct;80(5):612-7
pubmed: 19916698
Int J Surg. 2015 Dec;24(Pt B):147-53
pubmed: 26612525
Burns. 1996 Sep;22(6):443-6
pubmed: 8884002
Ultrasound Med Biol. 2016 Jan;42(1):185-95
pubmed: 26454624
Dermatol Surg. 2012 May;38(5):778-82
pubmed: 22335776
Burns. 2014 Dec;40(8):1513-20
pubmed: 24630820
Burns. 2016 May;42(3):508-18
pubmed: 26777448
Burns. 2012 Feb;38(1):19-25
pubmed: 21831527
Arch Phys Med Rehabil. 2007 Dec;88(12 Suppl 2):S3-6
pubmed: 18036978
Burns. 2005 Sep;31(6):696-702
pubmed: 15994014
Plast Reconstr Surg. 2004 Jun;113(7):1960-5; discussion 1966-7
pubmed: 15253184
Medicine (Baltimore). 2016 Aug;95(32):e4575
pubmed: 27512886
Burns. 2016 Nov;42(7):1455-1462
pubmed: 27233677
Burns. 2019 Feb;45(1):128-139
pubmed: 30626496
Int J Mol Med. 2018 Apr;41(4):1931-1938
pubmed: 29393337
FASEB J. 2006 May;20(7):811-27
pubmed: 16675838
Burns Trauma. 2016 Sep 19;4:34
pubmed: 27660766
Exp Ther Med. 2018 Jan;15(1):933-939
pubmed: 29434689
Burns. 2018 Feb;44(1):24-38
pubmed: 28669442
Int J Mol Sci. 2018 Jan 02;19(1):
pubmed: 29301325
Skin Res Technol. 2001 Feb;7(1):56-9
pubmed: 11301642
Wound Repair Regen. 2016 Mar;24(2):275-86
pubmed: 26808471
Burns. 2018 May;44(3):612-619
pubmed: 29029857