Maternal Microdeletion at the
Beckwith-Wiedemann Syndrome
DNA methylation
H19
Igf2
Methyl donor deficiency
antibiotic
epigenetics
genomic imprinting
pregnancy
succinylsulfathiozole
Journal
Epigenetics insights
ISSN: 2516-8657
Titre abrégé: Epigenet Insights
Pays: United States
ID NLM: 101735398
Informations de publication
Date de publication:
2020
2020
Historique:
received:
02
05
2020
accepted:
09
10
2020
entrez:
14
12
2020
pubmed:
15
12
2020
medline:
15
12
2020
Statut:
epublish
Résumé
Deficiency of methyl donor nutrients folate, choline, and methionine (methyl deficiency) during gestation can impair fetal development and perturb DNA methylation. Here, we assessed genetic susceptibility to methyl deficiency by comparing effects in wildtype C57BL/6J (B6) mice to mutant mice carrying a 1.3 kb deletion at the
Identifiants
pubmed: 33313480
doi: 10.1177/2516865720970575
pii: 10.1177_2516865720970575
pmc: PMC7716063
doi:
Types de publication
Journal Article
Langues
eng
Pagination
2516865720970575Subventions
Organisme : NIGMS NIH HHS
ID : F32 GM085999
Pays : United States
Organisme : NIEHS NIH HHS
ID : K22 ES023849
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK056350
Pays : United States
Organisme : NIEHS NIH HHS
ID : P30 ES010126
Pays : United States
Informations de copyright
© The Author(s) 2020.
Déclaration de conflit d'intérêts
Declaration of conflicting interests:The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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