The connectome of the adult Drosophila mushroom body provides insights into function.
D. melanogaster
behavior
dopamine
learning
memory
neuronal circuits
neuroscience
Journal
eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614
Informations de publication
Date de publication:
14 12 2020
14 12 2020
Historique:
received:
28
08
2020
accepted:
11
12
2020
pubmed:
15
12
2020
medline:
10
4
2021
entrez:
14
12
2020
Statut:
epublish
Résumé
Making inferences about the computations performed by neuronal circuits from synapse-level connectivity maps is an emerging opportunity in neuroscience. The mushroom body (MB) is well positioned for developing and testing such an approach due to its conserved neuronal architecture, recently completed dense connectome, and extensive prior experimental studies of its roles in learning, memory, and activity regulation. Here, we identify new components of the MB circuit in
Identifiants
pubmed: 33315010
doi: 10.7554/eLife.62576
pii: 62576
pmc: PMC7909955
doi:
pii:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Video-Audio Media
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Wellcome Trust
ID : 200846/Z/16/Z
Pays : United Kingdom
Organisme : Burroughs Wellcome Fund
ID : 1017109
Organisme : Medical Research Council
ID : MC_U105188491
Pays : United Kingdom
Organisme : Howard Hughes Medical Institute
Pays : United States
Organisme : NIBIB NIH HHS
ID : R01 EB029858
Pays : United States
Organisme : Department of Energy
ID : DE-SC0020347
Organisme : NIH HHS
ID : R01EB029858
Pays : United States
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : NINDS NIH HHS
ID : T32 NS064929
Pays : United States
Organisme : Howard Hughes Medical Institute
ID : internal funding
Pays : United States
Organisme : Wellcome Trust
ID : 203261/Z/16/Z
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC-U105188491
Pays : United Kingdom
Organisme : Simons Foundation
ID : SCGB
Organisme : National Science Foundation
ID : NeuroNex DBI-1707398
Informations de copyright
© 2020, Li et al.
Déclaration de conflit d'intérêts
FL, JL, EM, NO, MD, GD, IS, AB, MP, PS, AN, ST, NE, TY, AF, AB, RP, MC, LS, YA, GJ, LA, AL, SW, GR No competing interests declared
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