Women Are Less Likely to Be Tested for HIV or Offered Preexposure Prophylaxis at the Time of Sexually Transmitted Infection Diagnosis.


Journal

Sexually transmitted diseases
ISSN: 1537-4521
Titre abrégé: Sex Transm Dis
Pays: United States
ID NLM: 7705941

Informations de publication

Date de publication:
01 2021
Historique:
entrez: 14 12 2020
pubmed: 15 12 2020
medline: 25 5 2021
Statut: ppublish

Résumé

Ending the HIV epidemic requires linkage of at-risk individuals from diverse health care settings to comprehensive HIV prevention services. Sexually transmitted infections (STIs) are significant biomarkers of HIV risk and should trigger preexposure prophylaxis (PrEP) discussion. We reviewed STI testing practices outside of sexual health clinics to identify opportunities for improvement in the provision of HIV prevention services. An electronic sexual health dashboard was used to identify patient encounters with a positive gonorrhea, chlamydia, and/or rapid plasma reagin test result between January 1, 2019, and August 23, 2019, at a large urban academic medical center. A retrospective chart review was performed to assess HIV testing, completeness of STI screening, and HIV prevention discussion; inadequate screening was defined as no HIV test in 12 months before STI diagnosis. A total of 815 patients with 856 patient encounters were included. Patients were predominantly female (64.4%); median age was 24 years (range, 18-85 years). The most common test and most common positive test result was the genitourinary gonorrhea/chlamydia nucleic acid amplification test. Multisite testing was rare (7.5% of patient encounters) and performed more frequently in men than in women (20.3% vs. 0.36%). Women were also more likely to be inadequately screened for HIV (15.1% vs. 25.8%).Documentation of PrEP discussion was rare (4.7% of patient encounters) compared with safe sex (44.6%) and condoms (49.8%). Preexposure prophylaxis was discussed almost exclusively with men compared with women (17% vs. 1.1%). In patients diagnosed with bacterial STI outside of sexual health clinics, gaps in HIV prevention exist. HIV screening, multisite STI screening, and discussion of PrEP were particularly infrequent among women.

Sections du résumé

BACKGROUND
Ending the HIV epidemic requires linkage of at-risk individuals from diverse health care settings to comprehensive HIV prevention services. Sexually transmitted infections (STIs) are significant biomarkers of HIV risk and should trigger preexposure prophylaxis (PrEP) discussion. We reviewed STI testing practices outside of sexual health clinics to identify opportunities for improvement in the provision of HIV prevention services.
METHODS
An electronic sexual health dashboard was used to identify patient encounters with a positive gonorrhea, chlamydia, and/or rapid plasma reagin test result between January 1, 2019, and August 23, 2019, at a large urban academic medical center. A retrospective chart review was performed to assess HIV testing, completeness of STI screening, and HIV prevention discussion; inadequate screening was defined as no HIV test in 12 months before STI diagnosis.
RESULTS
A total of 815 patients with 856 patient encounters were included. Patients were predominantly female (64.4%); median age was 24 years (range, 18-85 years). The most common test and most common positive test result was the genitourinary gonorrhea/chlamydia nucleic acid amplification test. Multisite testing was rare (7.5% of patient encounters) and performed more frequently in men than in women (20.3% vs. 0.36%). Women were also more likely to be inadequately screened for HIV (15.1% vs. 25.8%).Documentation of PrEP discussion was rare (4.7% of patient encounters) compared with safe sex (44.6%) and condoms (49.8%). Preexposure prophylaxis was discussed almost exclusively with men compared with women (17% vs. 1.1%).
CONCLUSIONS
In patients diagnosed with bacterial STI outside of sexual health clinics, gaps in HIV prevention exist. HIV screening, multisite STI screening, and discussion of PrEP were particularly infrequent among women.

Identifiants

pubmed: 33315784
doi: 10.1097/OLQ.0000000000001265
pii: 00007435-202101000-00006
pmc: PMC8543120
mid: NIHMS1737989
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

32-36

Subventions

Organisme : NIAID NIH HHS
ID : L30 AI133789
Pays : United States

Références

Centers for Disease Control and Prevention. HIV Surveillance Report, 2018 (Preliminary). 2019. Available at: http://www.cdc.gov/hiv/library/reports/hiv-surveillance.html . Accessed February 22, 2020.
Center for Disease Control and Prevention. HIV Incidence: Estimated Annual Infections in the U.S., 2010–2016. Atlanta, GA: CDC, 2019.
Grant RM, Lama JR, Anderson PL, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med 2010; 363:2587–2599.
Baeten JM, Donnell D, Ndase P, et al. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. N Engl J Med 2012; 367:399–410.
Choopanya K, Martin M, Suntharasamai P, et al. Antiretroviral prophylaxis for HIV infection in injecting drug users in Bangkok, Thailand (the Bangkok Tenofovir Study): A randomised, double-blind, placebo-controlled phase 3 trial. Lancet 2013; 381:2083–2090.
PrEPWatch. United States. 2019; Available at: https://www.prepwatch.org/country/united-states/ . Accessed February 15, 2020.
Smith DK, Van Handel M, Wolitski RJ, et al. Vital signs: estimated percentages and numbers of adults with indications for preexposure prophylaxis to prevent HIV acquisition—United States, 2015. J Miss State Med Assoc 2015; 56:364–371.
Nguyen C, et al. Utilization of emtricitabine/tenofovir disoproxil fumarate (FTC/TDF) for HIV pre-exposure prophylaxis (PrEP) in the United States by age, gender, and race/ethnicity (2014–2017). Presented at: IAS 2019: Conference on HIV Pathogenesis, Treatment, and Prevention; July 21–24, 2019; Mexico City, Mexico.
Calabrese SK, Earnshaw VA, Underhill K, et al. The impact of patient race on clinical decisions related to prescribing HIV pre-exposure prophylaxis (PrEP): Assumptions about sexual risk compensation and implications for access. AIDS Behav 2014; 18:226–240.
Arrington-Sanders R, Hailey-Fair K, Wirtz AL, et al. Role of structural marginalization, HIV stigma, and mistrust on HIV prevention and treatment among young Black Latinx men who have sex with men and transgender women: Perspectives from youth service providers. AIDS Patient Care STDS 2020; 34:7–15.
Andrasik M, Broder G, Oseso L, et al. Stigma, implicit bias, and long-lasting prevention interventions to end the domestic HIV/AIDS epidemic. Am J Public Health 2020; 110:67–68.
Aaron E, Blum C, Seidman D, et al. Optimizing delivery of HIV preexposure prophylaxis for women in the United States. AIDS Patient Care STDS 2018; 32:16–23.
Peterman TA, Newman DR, Maddox L, et al. Risk for HIV following a diagnosis of syphilis, gonorrhoea or chlamydia: 328,456 women in Florida, 2000–2011. Int J STD AIDS 2015; 26:113–119.
Bernstein KT, Marcus JL, Nieri G, et al. Rectal gonorrhea and chlamydia reinfection is associated with increased risk of HIV seroconversion. J Acquir Immune Defic Syndr 2010; 53:537–543.
Pathela P, Slutsker J, JA S. Opportunities for HIV prevention: Screening for rectal chlamydia and gonorrhea among men who have sex with men in New York City. NYC Vital Signs 2018; 17:1–4.
Zucker J, Patterson B, Ellman T, et al. Missed opportunities for engagement in the prevention continuum in a predominantly Black and Latino community in New York City. AIDS Patient Care STDS 2018; 32:432–437.
Hess KM, Crawford J, Eanes A, et al. Reasons why young men who have sex with men report not using HIV pre-exposure prophylaxis: Perceptions of burden, need, and safety. AIDS Patient Care STDS 2019; 33:449–454.
Smith DK, Chang MH, Duffus WA, et al. Missed opportunities to prescribe preexposure prophylaxis in South Carolina, 2013–2016. Clin Infect Dis 2018; 68:37–42.
DiNapoli TP. An Economic Snapshot of Washington Heights and Inwood. New York, NY: Office of the State Comptroller, 2015.
AIDSVu: Local Data, New York City. New York: Emory University, Rollins School of Public Health, 2017.
Vail R.M. PrEP to prevent HIV and promote sexual health . 2020; Available at: https://www.hivguidelines.org/prep-for-prevention/prep/ . Accessed March 3, 2020.
Daskalakis D. PrEP for Women. New York: New York State Department of Health, 2018.
Workowski KA, Bolan GA; Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines, 2015. MMWR Recomm Rep 2015; 64:1–137.
Branson BM, Handsfield HH, Lampe MA, et al. Revised recommendations for HIV testing of adults, adolescents, and pregnant women in health-care settings. MMWR Recomm Rep 2006; 5:1–17.
Bamberger DM, Graham G, Dennis L, et al. Extragenital gonorrhea and chlamydia among men and women according to type of sexual exposure. Sex Transm Dis 2019; 46:329–334.
Habel MA, Leichliter JS, Dittus PJ, et al. Heterosexual anal and oral sex in adolescents and adults in the United States, 2011–2015. Sex Transm Dis 2018; 45:775–782.
Chan PA, Robinette A, Montgomery M, et al. Extragenital infections caused by Chlamydia trachomatis and Neisseria gonorrhoeae : A review of the literature. Infect Dis Obstet Gynecol 2016; 2016:5758387–5758387.
Sexually Transmitted Disease Surveillance 2018. Atlanta, GA: Centers for Disease Control and Prevention, 2019.
Schmidt R, Carson PJ, Jansen RJ. Resurgence of syphilis in the United States: An assessment of contributing factors. Infect Dis (Auckl) 2019; 12:1178633719883282.
Rodger AJ, Cambiano V, Bruun T, et al. Sexual activity without condoms and risk of HIV transmission in serodifferent couples when the HIV-positive partner is using suppressive antiretroviral therapy. JAMA 2016; 316:171–181.
Marcus JL, Snowden JM. Words matter: Putting an end to “unsafe” and “risky” sex. Sex Transm Dis 2020; 47:1–3.
Feller DJ, Zucker J, Don't Walk OB 4th, et al. Towards the inference of social and behavioral determinants of sexual health: Development of a gold-standard corpus with semi-supervised learning. AMIA Annu Symp Proc 2018; 2018:422–429.
Sexually Transmitted Disease Surveillance 2018. Atlanta, GA: Department of Health & Human Services, Centers fo Disease Control and Prevention:2019.
Logie CH, Turan JM. How do we balance tensions between COVID-19 public health responses and stigma mitigation? Learning from HIV research. AIDS Behav 2020; 24:2003–2006.
Tran NT, Tappis H, Spilotros N, et al. Not a luxury: A call to maintain sexual and reproductive health in humanitarian and fragile settings during the COVID-19 pandemic. Lancet Glob Health 2020; 8:e760–e761.

Auteurs

Caitlin Yumori (C)

From the Department of Internal Medicine, University of California Los Angeles, Los Angeles, CA.

Jason Zucker (J)

Department of Internal Medicine, Division of Infectious Diseases.

Deborah Theodore (D)

Department of Internal Medicine, Division of Infectious Diseases.

Michelle Chang (M)

Department of Internal Medicine, Columbia University Irving Medical Center.

Caroline Carnevale (C)

NewYork-Presbyterian Hospital.

Jacek Slowikowski (J)

NewYork-Presbyterian Hospital.

Elijah LaSota (E)

Department of Internal Medicine, Division of Infectious Diseases.

Susan Olender (S)

Department of Internal Medicine, Division of Infectious Diseases.

Peter Gordon (P)

Department of Internal Medicine, Division of Infectious Diseases.

Alwyn Cohall (A)

Department of Pediatrics, Columbia University Irving Medical Center, New York, NY.

Magdalena E Sobieszczyk (ME)

Department of Internal Medicine, Division of Infectious Diseases.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH