Associations between IVIM histogram parameters and histopathology in rectal cancer.
Histogram analysis
IVIM, rectal cancer
MRI
Microvessel density
Journal
Magnetic resonance imaging
ISSN: 1873-5894
Titre abrégé: Magn Reson Imaging
Pays: Netherlands
ID NLM: 8214883
Informations de publication
Date de publication:
04 2021
04 2021
Historique:
received:
20
10
2020
revised:
18
11
2020
accepted:
08
12
2020
pubmed:
15
12
2020
medline:
17
4
2021
entrez:
14
12
2020
Statut:
ppublish
Résumé
Histogram analysis can better reflect tumor heterogeneity than conventional imaging analysis. The present study analyzed possible correlations between histogram analysis parameters derived from Intravoxel-incoherent imaging (IVIM) and histopathological features in rectal cancer (RC). Seventeen patients with histopathologically proven rectal adenocarcinomas were retrospectively acquired. In all cases, pelvic MRI was performed. Diffusion weighted imaging was obtained using a multi-slice single-shot echo-planar imaging sequence with b values of 0, 50, 200, 500 and 1000 s/mm There were statistically significant correlations between Ki 67 index and mode derived from ADC as well as entropy from f, r=-0.50, p=.04 and r=-0.55, p=.02, respectively. MVD correlated well with parameters derived from f. IVIM histogram analysis parameters can reflect histopathology in RC. ADC and D values are associated with proliferation potential. Perfusion fraction f is associated with MVD.
Identifiants
pubmed: 33316358
pii: S0730-725X(20)30656-1
doi: 10.1016/j.mri.2020.12.008
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
21-27Informations de copyright
Copyright © 2020. Published by Elsevier Inc.