Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
09 Dec 2020
Historique:
received: 17 09 2020
revised: 04 12 2020
accepted: 08 12 2020
entrez: 15 12 2020
pubmed: 16 12 2020
medline: 3 3 2021
Statut: epublish

Résumé

Carotid atherosclerotic plaque rupture can lead to cerebrovascular accident (CVA). By comparing RNA-Seq data from vascular smooth muscle cells (VSMC) extracted from carotid atheroma surgically excised from a group of asymptomatic and symptomatic subjects, we identified more than 700 genomic variants associated with symptomatology (

Identifiants

pubmed: 33317170
pii: ijms21249387
doi: 10.3390/ijms21249387
pmc: PMC7763522
pii:
doi:

Substances chimiques

BIRC6 protein, human 0
Inhibitor of Apoptosis Proteins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Eusko Jaurlaritza
ID : PIBA2018-67
Organisme : Osasun Saila, Eusko Jaurlaritzako
ID : RIS3-2019222038
Organisme : Instituto de Salud Carlos III
ID : RD16/0019/0007
Organisme : Secretaría Nacional de Ciencia, Tecnología e Innovación
ID : BIDP-III-2018-12
Organisme : RefbioII Trans-Pyrenean Cooperation Network for Biomedical Research
ID : IKERIKTUS
Organisme : Maratón EiTB 2017 for Funding of Research into Stroke
ID : BIO18/IC/005

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Auteurs

Iraide Alloza (I)

Inflammation & Biomarkers Group, Biocruces Bizkaia Health Research Institute, 48903 Barakaldo, Spain.
Department of Biochemistry and Molecular Biology, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.

Andrea Salegi (A)

Inflammation & Biomarkers Group, Biocruces Bizkaia Health Research Institute, 48903 Barakaldo, Spain.
Department of Biochemistry and Molecular Biology, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.

Jorge Mena (J)

Inflammation & Biomarkers Group, Biocruces Bizkaia Health Research Institute, 48903 Barakaldo, Spain.
Department of Biochemistry and Molecular Biology, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.

Raquel Tulloch Navarro (RT)

Inflammation & Biomarkers Group, Biocruces Bizkaia Health Research Institute, 48903 Barakaldo, Spain.
Department of Biochemistry and Molecular Biology, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.

César Martin (C)

Biofisika Institute (UPV/EHU, CSIC), 48940 Leioa, Spain.

Patricia Aspichueta (P)

Department of Physiology, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.
Biocruces Bizkaia Health Research Institute, 48903 Barakaldo, Spain.

Lucía Martínez Salazar (LM)

Department of Laboratory Medicine, Osakidetza, Bilbao-Basurto IHO, Basurto University Hospital, 48013 Bilbao, Spain.

Jon Uriarte Carpio (JU)

Department of Laboratory Medicine, Osakidetza, Bilbao-Basurto IHO, Basurto University Hospital, 48013 Bilbao, Spain.

Patricia De-la-Hera Cagigal (PD)

Department of Laboratory Medicine, Osakidetza, Bilbao-Basurto IHO, Basurto University Hospital, 48013 Bilbao, Spain.

Reyes Vega (R)

Neurovascular Group, Biocruces Bizkaia Health Research Institute, 48903 Barakaldo, Spain.

Juan Carlos Triviño (JC)

Sistemas Genómicos, 46980 Peterna, Spain.

Maria Del Mar Freijo (MDM)

Neurovascular Group, Biocruces Bizkaia Health Research Institute, 48903 Barakaldo, Spain.

Koen Vandenbroeck (K)

Inflammation & Biomarkers Group, Biocruces Bizkaia Health Research Institute, 48903 Barakaldo, Spain.
Department of Biochemistry and Molecular Biology, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.
Ikerbasque, Basque Foundation for Science, 48013 Bilbao, Spain.

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Classifications MeSH