Neglected side effects to curative prostate cancer treatments.


Journal

International journal of impotence research
ISSN: 1476-5489
Titre abrégé: Int J Impot Res
Pays: England
ID NLM: 9007383

Informations de publication

Date de publication:
May 2021
Historique:
received: 18 08 2020
accepted: 24 11 2020
revised: 17 11 2020
pubmed: 16 12 2020
medline: 21 5 2021
entrez: 15 12 2020
Statut: ppublish

Résumé

In this narrative review we summarize neglected side effects of curative intended treatment for prostate cancer. They include climacturia, arousal incontinence (AI), orgasmic disturbances such as altered orgasmic sensation, anorgasmia, and orgasm-associated pain (dysorgasmia), ejaculatory dysfunction, and morphological penile alterations in the form of shortening and deformity. Even though they have not received as much interest as erectile dysfunction (ED) or urinary incontinence, these side effects have been shown to negatively impact patient's quality of life. They are common and rates of climacturia after radical prostatectomy (RP) range from 20% and 45%, less after external beam radiation therapy (EBRT). Decreased orgasmic sensation ranges from 3.9% to 60% after RP and between 36-57% after EBRT. Dysorgasmia ranges from 9.5-15% for both RP and EBRT. Anejculation after EBRT ranges from 11-71% and rates of penile shortening are reported between 0 and 100%. There are no internationally validated questionnaires that adequately asses these side effects. This is necessary if we are to align patient and partner expectations properly and consequently manage them optimally. Neglected side effects should be discussed with patients and their partners preoperatively, as they are associated with bother and may lead to patient's avoiding sexual activity.

Identifiants

pubmed: 33318637
doi: 10.1038/s41443-020-00386-4
pii: 10.1038/s41443-020-00386-4
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

428-438

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Auteurs

Alexander B Nolsøe (AB)

Department of Urology, Herlev and Gentofte Hospital, Herlev, Denmark.
Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark.

Christian Fuglesang S Jensen (CFS)

Department of Urology, Herlev and Gentofte Hospital, Herlev, Denmark.
Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark.

Peter B Østergren (PB)

Department of Urology, Herlev and Gentofte Hospital, Herlev, Denmark.
Department of Urology, Zealand University Hospital, Roskilde, Denmark.

Mikkel Fode (M)

Department of Urology, Herlev and Gentofte Hospital, Herlev, Denmark. mimf@regionsjaelland.dk.
Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark. mimf@regionsjaelland.dk.
Department of Urology, Zealand University Hospital, Roskilde, Denmark. mimf@regionsjaelland.dk.

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