Adult form of Langerhans cell histiocytosis with pulmonary and hepatic involvement mimicking malignancy in a patient with chronic hepatitis C infection.
Carcinoma
Hepatitis C
Hepatocellular
Langerhans cell histiocytosis
Liver
Liver cirrhosis
Journal
Radiology case reports
ISSN: 1930-0433
Titre abrégé: Radiol Case Rep
Pays: Netherlands
ID NLM: 101467888
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
received:
12
08
2020
revised:
09
11
2020
accepted:
11
11
2020
entrez:
15
12
2020
pubmed:
16
12
2020
medline:
16
12
2020
Statut:
epublish
Résumé
Langerhans cell histiocytosis (LCH) is a myeloid neoplasm with inflammatory properties. There are few published reports of adult LCH with liver involvement, which is still poorly understood, but shows high morbidity and mortality. We report a case of a 37-year-old woman suffering from hepatitis C showing a LCH affecting the lung as well as the liver. Consistent with histology, we found an early stage of a proliferative/granulomatous phase of hepatobiliary LCH, whereas pulmonary findings showed a nodular stage of adult pulmonary LCH. Although hepatocellular carcinoma is a common malignancy in patients suffering from hepatitis C, it is crucial to keep in mind differential diagnosis for newly appearing liver lesions.
Identifiants
pubmed: 33318775
doi: 10.1016/j.radcr.2020.11.022
pii: S1930-0433(20)30598-7
pmc: PMC7724096
doi:
Types de publication
Case Reports
Langues
eng
Pagination
327-333Commentaires et corrections
Type : ErratumIn
Informations de copyright
© 2020 Published by Elsevier Inc. on behalf of University of Washington.
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