Developing [60]Fullerene Nanomaterials for Better Photodynamic Treatment of Non-Melanoma Skin Cancers.
EPR spin trapping
[60]fullerene
lipid peroxidation
non-melanoma skin cancer
photodynamic therapy
singlet oxygen
Journal
ACS biomaterials science & engineering
ISSN: 2373-9878
Titre abrégé: ACS Biomater Sci Eng
Pays: United States
ID NLM: 101654670
Informations de publication
Date de publication:
12 10 2020
12 10 2020
Historique:
entrez:
15
12
2020
pubmed:
16
12
2020
medline:
20
5
2021
Statut:
ppublish
Résumé
Skin cancer is the most common cancer in the U.S.A. and Europe. Its subtype, squamous skin carcinoma (SCC), if allowed to grow, has the potential to metastasize and can become deadly. Currently, carbon nanomaterials are being developed to treat cancer due to their attractive physicochemical and biological properties such as an enhanced permeability effect and their ability to produce reactive oxygen species. Here, we describe the synthesis of two water-soluble aminofullerenes (MonoaminoC
Identifiants
pubmed: 33320587
doi: 10.1021/acsbiomaterials.0c00932
doi:
Substances chimiques
Fullerenes
0
Reactive Oxygen Species
0
Singlet Oxygen
17778-80-2
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM