The development of marine biomaterial derived from decellularized squid mantle for potential application as tissue engineered urinary conduit.

Animals Biocompatible Materials Decapodiformes Extracellular Matrix Swine Tissue Engineering Tissue Scaffolds Urinary Bladder Urothelium
Decellularized biomaterial Marine biomaterial Reconstructive urology Tissue engineering Urinary conduit

Journal

Materials science & engineering. C, Materials for biological applications
ISSN: 1873-0191
Titre abrégé: Mater Sci Eng C Mater Biol Appl
Pays: Netherlands
ID NLM: 101484109

Informations de publication

Date de publication:
Feb 2021
Historique:
received: 23 06 2020
revised: 12 08 2020
accepted: 24 09 2020
entrez: 16 12 2020
pubmed: 17 12 2020
medline: 15 5 2021
Statut: ppublish

Résumé

Tissue engineering is focusing research effort on search for new biomaterials that might be applied to create artificial urinary conduit. Nevertheless, the demanding biomechanical characteristics necessary for proper conduit function is difficult to be replicated. In this study, we are introducing novel marine biomaterial obtained by decellularization of squid mantle derived from Loligo vulgaris. Squid mantles underwent decellularization according to developed dynamic flow two-staged procedure. Efficacy of the method was confirmed by computational dynamic flow analysis. Subsequently Decellularized Squid Mantle (DSM) underwent extensive histological analysis and mechanical evaluation. Based on gained biomechanical data the computational modelling using finite element method was utilized to simulate behavior of DSM used as a urinary conduit. Taking into account potential application in reconstructive urology, the DSM was then evaluated as a scaffold for urothelial and smooth muscle cells derived from porcine urinary bladder. Conducted analysis showed that DSM created favorable environment for cells growth. In addition, due to polarized structure and natural external polysaccharide layer, it protected seeded cells from urine.

Identifiants

DOI: 10.1016/j.msec.2020.111579 PMID: 33321625
pubmed: 33321625
pii: S0928-4931(20)33497-4
doi: 10.1016/j.msec.2020.111579
pii:
doi:

Substances chimiques

Biocompatible Materials 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

111579

Informations de copyright

Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.

Auteurs

J Adamowicz (J)

Chair of Urology, Department of Regenerative Medicine, Collegium Medicum, Nicolaus Copernicus University, Curie-Skłodowskiej 9, 85-094 Bydgoszcz, Poland; Reconstructive Urology Working Group, Young Academic Urologists, European Association of Urology, the Netherlands. Electronic address: adamowicz.jz@gmail.com.

T Kloskowski (T)

Chair of Urology, Department of Regenerative Medicine, Collegium Medicum, Nicolaus Copernicus University, Curie-Skłodowskiej 9, 85-094 Bydgoszcz, Poland.

M Stopel (M)

Department of Mechanics and Computer Methods, University of Science and Technology, Kaliskiego 7, 85-796 Bydgoszcz, Poland.

M Gniadek (M)

Department of Fundamentals of Machine Design and Biomedical Engineering, University of Science and Technology, Kaliskiego 7, 85-796 Bydgoszcz, Poland.

M Rasmus (M)

Chair of Urology, Department of Regenerative Medicine, Collegium Medicum, Nicolaus Copernicus University, Curie-Skłodowskiej 9, 85-094 Bydgoszcz, Poland.

D Balcerczyk (D)

Chair of Urology, Department of Regenerative Medicine, Collegium Medicum, Nicolaus Copernicus University, Curie-Skłodowskiej 9, 85-094 Bydgoszcz, Poland.

M Buhl (M)

Chair of Urology, Department of Regenerative Medicine, Collegium Medicum, Nicolaus Copernicus University, Curie-Skłodowskiej 9, 85-094 Bydgoszcz, Poland.

M Gagat (M)

Department of Histology and Embryology, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz Curie-Skłodowskiej 9, 85-094 Bydgoszcz, Poland.

P Antosik (P)

Department of Clinical Pathomorphology, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz Curie-Skłodowskiej 9, 85-094 Bydgoszcz, Poland.

D Grzanka (D)

Department of Clinical Pathomorphology, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz Curie-Skłodowskiej 9, 85-094 Bydgoszcz, Poland.

A Sionkowska (A)

Department of Chemistry of Biomaterials and Cosmetics, Nicolaus Copernicus University, Gagarina 11, 87-100 Torun, Poland.

T Drewa (T)

Chair of Urology, Department of Regenerative Medicine, Collegium Medicum, Nicolaus Copernicus University, Curie-Skłodowskiej 9, 85-094 Bydgoszcz, Poland.

M Pokrywczynska (M)

Chair of Urology, Department of Regenerative Medicine, Collegium Medicum, Nicolaus Copernicus University, Curie-Skłodowskiej 9, 85-094 Bydgoszcz, Poland.

Articles similaires

Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials.

Sudhir Prem Srivastava, Vishwajyoti Pascual Srivastava, Avinesh Singh et al.
1.00
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Use of organic material provided by an automatic enrichment device by weaner pigs and its influence on tail lesions.

Philipp Heseker, Jeanette Probst, Stefanie Ammer et al.
1.00
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › The development of marine biomaterial derived...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Matériaux biocompatibles › The development of marine biomaterial derived...
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Mollusca › Cephalopoda › Decapodiformes › The development of marine biomaterial derived...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace extracellulaire › Matrice extracellulaire › The development of marine biomaterial derived...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Artiodactyla › Suidae › The development of marine biomaterial derived...
questionsmedicales.fr › Technologie, industrie et agriculture › Ingénierie › Bioingénierie › Ingénierie cellulaire › Ingénierie tissulaire › The development of marine biomaterial derived...
questionsmedicales.fr › Équipement et fournitures › Prothèses et implants › Structures d'échafaudage tissulaires › The development of marine biomaterial derived...
questionsmedicales.fr › Appareil urogénital › Voies urinaires › Vessie urinaire › The development of marine biomaterial derived...
questionsmedicales.fr › Tissus › Épithélium › Urothélium › The development of marine biomaterial derived...