Case Report: Myelin Oligodendrocyte Glycoprotein Antibody-Associated Relapse With COVID-19.

Devic's disease autoimmune diseases myelin-oligodendrocyte glycoprotein (MOG) optic neuritis post-infectious visual loss

Journal

Frontiers in neurology
ISSN: 1664-2295
Titre abrégé: Front Neurol
Pays: Switzerland
ID NLM: 101546899

Informations de publication

Date de publication:
2020
Historique:
received: 24 08 2020
accepted: 19 10 2020
entrez: 16 12 2020
pubmed: 17 12 2020
medline: 17 12 2020
Statut: epublish

Résumé

A 39-year-old lady with relapsing myelin oligodendrocyte glycoprotein antibody (MOG-IgG) associated disease developed coryzal symptoms, malaise, sweating, and postural dizziness. Six days later she presented with painful progressive right visual loss consistent with optic neuritis. COVID-19 was confirmed by nasopharyngeal swab and MOG-IgG serological reversion was noted. Visual function improved following steroids and plasma exchange. This case highlights a possible causal association between inflammation due to COVID-19 and a relapse of MOG-IgG associated disease. It also highlights the clinical relevance of reporting MOG-IgG titers in MOG-IgG associated disease.

Identifiants

pubmed: 33324337
doi: 10.3389/fneur.2020.598531
pmc: PMC7724101
doi:

Types de publication

Case Reports

Langues

eng

Pagination

598531

Informations de copyright

Copyright © 2020 Woodhall, Mitchell, Gibbons, Healy, Waters and Huda.

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Auteurs

Mark Woodhall (M)

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.

James W Mitchell (JW)

Department of Neurology, Walton Centre NHS Foundation Trust, Liverpool, United Kingdom.
Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, United Kingdom.

Emily Gibbons (E)

Department of Neurology, Walton Centre NHS Foundation Trust, Liverpool, United Kingdom.

Sarah Healy (S)

Department of Neurology, Walton Centre NHS Foundation Trust, Liverpool, United Kingdom.

Patrick Waters (P)

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.

Saif Huda (S)

Department of Neurology, Walton Centre NHS Foundation Trust, Liverpool, United Kingdom.

Classifications MeSH