Dynamics of Internalization and Intracellular Interaction of Tau Antibodies and Human Pathological Tau Protein in a Human Neuron-Like Model.

Alzheimer's disease PHF antibodies immunotherapies live imaging tau

Journal

Frontiers in neurology
ISSN: 1664-2295
Titre abrégé: Front Neurol
Pays: Switzerland
ID NLM: 101546899

Informations de publication

Date de publication:
2020
Historique:
received: 02 09 2020
accepted: 02 11 2020
entrez: 16 12 2020
pubmed: 17 12 2020
medline: 17 12 2020
Statut: epublish

Résumé

We and others have shown in various

Identifiants

pubmed: 33324339
doi: 10.3389/fneur.2020.602292
pmc: PMC7727311
doi:

Types de publication

Journal Article

Langues

eng

Pagination

602292

Subventions

Organisme : NIMH NIH HHS
ID : T32 MH096331
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA016087
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG032611
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG020197
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS077239
Pays : United States
Organisme : NIH HHS
ID : R24 OD018339
Pays : United States
Organisme : NINDS NIH HHS
ID : T32 NS069514
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR000038
Pays : United States
Organisme : NIH HHS
ID : U42 OD011158
Pays : United States
Organisme : NIH HHS
ID : R24 OD018340
Pays : United States

Informations de copyright

Copyright © 2020 Shamir, Deng, Wu, Modak, Congdon and Sigurdsson.

Déclaration de conflit d'intérêts

ES is an inventor on patents on tau immunotherapy and related diagnostics that are assigned to New York University. Some of this technology is licensed to and is being co-developed with H. Lundbeck A/S. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

Neurobiol Dis. 2020 Apr;137:104770
pubmed: 31982516
J Biol Chem. 2013 Nov 15;288(46):33081-95
pubmed: 24089520
Mol Neurodegener. 2016 Aug 30;11(1):62
pubmed: 27578006
EBioMedicine. 2019 Apr;42:157-173
pubmed: 30910484
Methods Mol Biol. 2018;1779:513-526
pubmed: 29886554
Trends Neurosci. 2005 Sep;28(9):464-71
pubmed: 16040136
Acta Neuropathol. 2020 Jan;139(1):3-25
pubmed: 31686182
J Biol Chem. 2012 Jun 8;287(24):20522-33
pubmed: 22496370
Neuropharmacology. 2020 Sep 15;175:108104
pubmed: 32360477
Biochem Biophys Res Commun. 2004 Jul 2;319(3):993-1000
pubmed: 15184080
Immunol Rev. 2015 Nov;268(1):25-51
pubmed: 26497511
Dev Neurobiol. 2010 Apr;70(5):304-22
pubmed: 20186705
Nat Neurosci. 2007 Jun;10(6):702-11
pubmed: 17515902
J Neurochem. 2011 Aug;118(4):658-67
pubmed: 21644996
J Biol Chem. 2013 Dec 6;288(49):35452-65
pubmed: 24163366
Neurobiol Dis. 2007 May;26(2):353-62
pubmed: 17398105
J Biol Chem. 2014 Jan 10;289(2):956-67
pubmed: 24235150
Nature. 2015 Jul 23;523(7561):431-436
pubmed: 26176913
Acta Neuropathol. 2011 Sep;122(3):285-92
pubmed: 21630115
MAbs. 2019 Apr;11(3):477-488
pubmed: 30794086
Brain. 2014 Oct;137(Pt 10):2834-46
pubmed: 25085375
Front Psychiatry. 2011 Oct 21;2:59
pubmed: 22025915
Cell Mol Neurobiol. 2017 Jan;37(1):121-131
pubmed: 26961542
EBioMedicine. 2018 Sep;35:270-278
pubmed: 30146345
Nat Rev Neurol. 2018 Jul;14(7):399-415
pubmed: 29895964
J Alzheimers Dis. 2010;21(3):795-811
pubmed: 20634587
Sci Rep. 2014 Nov 20;4:7130
pubmed: 25410733
Nat Neurosci. 2005 Feb;8(2):164-72
pubmed: 15665879
Alzheimers Dement. 2016 Oct;12(10):1098-1107
pubmed: 27016263
Anat Cell Biol. 2010 Sep;43(3):201-10
pubmed: 21212860
J Neurosci. 2007 Aug 22;27(34):9115-29
pubmed: 17715348
Methods Mol Biol. 2018;1779:371-379
pubmed: 29886544
Methods Enzymol. 1999;309:81-9
pubmed: 10507018
J Neurosci. 2004 Apr 21;24(16):4070-81
pubmed: 15102922
J Psychiatr Res. 2007 Aug;41(5):387-94
pubmed: 16554070
Curr Protoc Cell Biol. 2009 Sep;Chapter 3:Unit 3.33 3.33.1-33
pubmed: 19731227
J Neurochem. 2000 Sep;75(3):991-1003
pubmed: 10936180
J Neurobiol. 2002 Apr;51(1):9-23
pubmed: 11920724
J Neurosci. 2011 Aug 17;31(33):11894-904
pubmed: 21849550
J Biol Chem. 2015 Aug 28;290(35):21652-62
pubmed: 26126828
Sci Rep. 2015 Jun 09;5:11161
pubmed: 26057852
Neurobiol Dis. 2020 Feb;134:104707
pubmed: 31841678
J Biol Chem. 2014 Jul 18;289(29):19855-61
pubmed: 24860099
Brain. 2014 Mar;137(Pt 3):834-48
pubmed: 24477431
J Neurosci. 2014 Dec 10;34(50):16835-50
pubmed: 25505335
Sci Rep. 2014 Nov 13;4:7026
pubmed: 25391618
PLoS One. 2012;7(5):e35921
pubmed: 22615744
J Biol Chem. 2013 Jan 18;288(3):1856-70
pubmed: 23188818
Brain. 2017 May 1;140(5):1220-1230
pubmed: 28379300
Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):574-579
pubmed: 28049840
Cytometry A. 2010 Aug;77(8):733-42
pubmed: 20653013
PLoS Biol. 2013;11(2):e1001478
pubmed: 23424281
J Alzheimers Dis. 2010;20(4):1069-82
pubmed: 20413890
Sci Rep. 2019 Mar 15;9(1):4658
pubmed: 30874605

Auteurs

Dov B Shamir (DB)

Department of Neuroscience and Physiology, Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, United States.

Yan Deng (Y)

Microscopy Core, New York University Grossman School of Medicine, New York, NY, United States.

Qian Wu (Q)

Department of Neuroscience and Physiology, Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, United States.

Swananda Modak (S)

Department of Neuroscience and Physiology, Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, United States.

Erin E Congdon (EE)

Department of Neuroscience and Physiology, Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, United States.

Einar M Sigurdsson (EM)

Department of Neuroscience and Physiology, Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, United States.
Department of Psychiatry, New York University Grossman School of Medicine, New York, NY, United States.

Classifications MeSH