The growing role of precision medicine for the treatment of autoimmune diseases; results of a systematic review of literature and Experts' Consensus.

Autoimmune Diseases / therapy Consensus Humans Lupus Erythematosus, Systemic Precision Medicine Sjogren's Syndrome
Precision medicine antiphospholipid syndrome primary Sjogren’s syndrome rheumatoid arthritis spondyloarthritides systemic lupus erythematosus systemic sclerosis

Journal

Autoimmunity reviews
ISSN: 1873-0183
Titre abrégé: Autoimmun Rev
Pays: Netherlands
ID NLM: 101128967

Informations de publication

Date de publication:
Feb 2021
Historique:
received: 13 09 2020
accepted: 22 09 2020
pubmed: 17 12 2020
medline: 16 2 2021
entrez: 16 12 2020
Statut: ppublish

Résumé

Autoimmune diseases (AIDs) share similar serological, clinical, and radiological findings, but, behind these common features, there are different pathogenic mechanisms, immune cells dysfunctions, and targeted organs. In this context, multiple lines of evidence suggest the application of precision medicine principles to AIDs to reduce the treatment failure. Precision medicine refers to the tailoring of therapeutic strategies to the individual characteristics of each patient, thus it could be a new approach for management of AIDS which considers individual variability in genes, environmental exposure, and lifestyle. Precision medicine would also assist physicians in choosing the right treatment, the best timing of administration, consequently trying to maximize drug efficacy, and, possibly, reducing adverse events. In this work, the growing body of evidence is summarized regarding the predictive factors for drug response in patients with AIDs, applying the precision medicine principles to provide high-quality evidence for therapeutic opportunities in improving the management of these patients.

Identifiants

DOI: 10.1016/j.autrev.2020.102738 PMID: 33326854
pubmed: 33326854
pii: S1568-9972(20)30319-0
doi: 10.1016/j.autrev.2020.102738
pii:
doi:

Types de publication

Journal Article Review Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

102738

Subventions

Organisme : Versus Arthritis
ID : 21268
Pays : United Kingdom
Organisme : Department of Health
ID : 11/100/76
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/K015346/1
Pays : United Kingdom
Organisme : Department of Health
ID : TRF-2018-11-ST2-002
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/N003063/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : G0800648
Pays : United Kingdom

Informations de copyright

Copyright © 2020. Published by Elsevier B.V.

Auteurs

Roberto Giacomelli (R)

Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy. Electronic address: roberto.giacomelli@cc.univaq.it.

Antonella Afeltra (A)

Unit of Allergology, Immunology and Rheumatology, Department of Medicine, Università Campus Bio-Medico di Roma, Rome, Italy.

Elena Bartoloni (E)

Rheumatology Unit, Department of Medicine, University of Perugia, Italy.

Onorina Berardicurti (O)

Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

Michele Bombardieri (M)

Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

Alessandra Bortoluzzi (A)

Department of Clinical and Experimental Medicine, Rheumatology Unit, Sant'anna Hospital, University of Ferrara, Ferrara, Italy.

Francesco Carubbi (F)

Department of Medicine, ASL1 Avezzano Sulmona L'Aquila, L'Aquila, Italy.

Francesco Caso (F)

Rheumatology Unit, Department of Clinical Medicine and Surgery, School of Medicine, University of Naples Federico II, Naples, Italy.

Ricard Cervera (R)

Autoimmune Diseases, Hospital Clinic, University of Barcelona, Barcelona, Catalonia, Spain.

Francesco Ciccia (F)

Rheumatology Section, Department of Clinical and Precision Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

Paola Cipriani (P)

Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

Emmanuel Coloma-Bazán (E)

Autoimmune Diseases, Hospital Clinic, University of Barcelona, Barcelona, Catalonia, Spain.

Fabrizio Conti (F)

Rheumatology Unit, Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.

Luisa Costa (L)

Rheumatology Unit, Department of Clinical Medicine and Surgery, School of Medicine, University of Naples Federico II, Naples, Italy.

Salvatore D'Angelo (S)

Rheumatology Institute of Lucania (IReL), San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, Potenza, Italy.

Oliver Distler (O)

Department of Rheumatology, University Hospital Zurich, Switzerland.

Eugen Feist (E)

Helios Department of Rheumatology, Sophie-v.-Boetticher-Straße 1, 39245 Gommern, Germany.

Nathan Foulquier (N)

LATIM, Laboratoire de Traitement de l'Information Médicale, UMR 1101, IBRBS, Université de Brest, Inserm, CHU, France.

Marco Gabini (M)

UOC Reumatologia, Presidio Ospedaliero "Santo Spirito", Pescara, Italy.

Vanessa Gerber (V)

Department of Rheumatology, University Hospital Zurich, Switzerland.

Roberto Gerli (R)

Rheumatology Unit, Department of Medicine, University of Perugia, Italy.

Rosa Daniela Grembiale (RD)

Department of Health Sciences, University of Catanzaro "Magna Graecia"; Catanzaro, Italy.

Giuliana Guggino (G)

Rheumatology Unit, Department of Medicine-DIMED, University of Padova, Italy.

Ariela Hoxha (A)

Internal Medicine Unit, Department of Medicine, San Bortolo Hospital, Vicenza, and Rheumatology Unit, Department of Medicine-DIMED, University of Padova, Italy.

Annamaria Iagnocco (A)

Academic Rheumatology Centre, DSCB, Università degli Studi di Torino, Torino, Italy.

Suzana Jordan (S)

Department of Rheumatology, University Hospital Zurich, Switzerland.

Bashar Kahaleh (B)

Division of Rheumatology and Immunology, Department of Internal Medicine, University of Toledo Medical Center, Toledo, OH, USA.

Kim Lauper (K)

Division of Rheumatology, Geneva University Hospitals & Faculty of Medicine, University of Geneva, Geneva, Switzerland.

Vasiliki Liakouli (V)

Autoimmune Diseases, Hospital Clinic, University of Barcelona, Barcelona, Catalonia, Spain.

Ennio Lubrano (E)

Academic Rheumatology Unit, Dipartimento Di Medicina E Scienze, Della Salute "Vincenzo Tiberio", Università Degli Studi del Molise, Campobasso, Italy.

Domenico Margiotta (D)

Unit of Allergology, Immunology and Rheumatology, Department of Medicine, Università Campus Bio-Medico di Roma, Rome, Italy.

Saverio Naty (S)

Department of Health Sciences, University of Catanzaro "Magna Graecia"; Catanzaro, Italy.

Luca Navarini (L)

Unit of Allergology, Immunology and Rheumatology, Department of Medicine, Università Campus Bio-Medico di Roma, Rome, Italy.

Federico Perosa (F)

Rheumatic and Systemic Autoimmune Diseases Unit, Department of Biomedical Sciences and Human Oncology, University of Bari Medical School, Bari, Italy.

Carlo Perricone (C)

Rheumatology Unit, Department of Medicine, University of Perugia, Italy.

Roberto Perricone (R)

Rheumatology Unit, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.

Marcella Prete (M)

Rheumatic and Systemic Autoimmune Diseases Unit, Department of Biomedical Sciences and Human Oncology, University of Bari Medical School, Bari, Italy.

Jacques-Olivier Pers (JO)

UMR1227, Lymphocytes B et Autoimmunité, Univ de Brest, Inserm, CHU de Brest, LabEx IGO, Brest, France.

Costantino Pitzalis (C)

Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

Roberta Priori (R)

Rheumatology Unit, Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.

Felice Rivellese (F)

Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

Amelia Ruffatti (A)

Internal Medicine Unit, Department of Medicine, San Bortolo Hospital, Vicenza, and Rheumatology Unit, Department of Medicine-DIMED, University of Padova, Italy.

Piero Ruscitti (P)

Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

Raffaele Scarpa (R)

Rheumatology Unit, Department of Clinical Medicine and Surgery, School of Medicine, University of Naples Federico II, Naples, Italy.

Yehuda Shoenfeld (Y)

Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel HaShomer, Ramat Gan, Israel; Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv-Yafo, Israel; I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Russia.

Giovanni Triolo (G)

Rheumatology Unit, Department of Medicine-DIMED, University of Padova, Italy.

Athanasios Tzioufas (A)

Pathophysiology Department, Athens School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Maladies du système immunitaire › Maladies auto-immunes › The growing role of precision medicine for the...
questionsmedicales.fr › Phénomènes psychologiques › Processus mentaux › Pensée (activité mentale) › Prise de décision › Consensus › The growing role of precision medicine for the...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The growing role of precision medicine for the...
questionsmedicales.fr › Maladies du système immunitaire › Maladies auto-immunes › Lupus érythémateux disséminé › The growing role of precision medicine for the...
questionsmedicales.fr › Professions de santé › Médecine › Médecine clinique › Médecine de précision › The growing role of precision medicine for the...
questionsmedicales.fr › Maladies du système immunitaire › Maladies auto-immunes › Polyarthrite rhumatoïde › Syndrome de Gougerot-Sjögren › The growing role of precision medicine for the...