No differences in hemostatic and endothelial activations between haploidentical and matched-donor hematopoietic stem cell transplantation in thalassemia disease.

Endothelial activation Haploidentical hematopoietic stem cell transplantation Hemostasis Thalassemia

Journal

Thrombosis journal
ISSN: 1477-9560
Titre abrégé: Thromb J
Pays: England
ID NLM: 101170542

Informations de publication

Date de publication:
04 Sep 2020
Historique:
received: 12 05 2020
accepted: 07 08 2020
entrez: 17 12 2020
pubmed: 18 12 2020
medline: 18 12 2020
Statut: epublish

Résumé

Hemostatic changes and endothelial activations have been recognized in β-thalassemic patients after matched-donor hematopoietic stem cell transplantation (HSCT) but there are limited studies for haploidentical HSCT. This report demonstrates that the levels of hemostatic and endothelial markers, including thrombin antithrombin complex, prothrombin fragment, D-dimer, von Willebrand factor antigen and thrombomodulin levels, were not significantly different between haploidentical and matched-donor HSCT patients.

Identifiants

pubmed: 33327955
doi: 10.1186/s12959-020-00232-z
pii: 10.1186/s12959-020-00232-z
pmc: PMC7739460
doi:

Types de publication

Letter

Langues

eng

Pagination

21

Subventions

Organisme : Mahidol University
ID : RF_59023

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Auteurs

Surapong Lertthammakiat (S)

Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Ratchathewi District, Bangkok, Thailand.
Chakri Naruebodindr Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samut Prakan, Thailand.

Peerasit Sitthirat (P)

Department of Biology, Mahidol Wittayanusorn School, Nakhon Pathom, Thailand.

Usanarat Anurathapan (U)

Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Ratchathewi District, Bangkok, Thailand.

Duantida Songdej (D)

Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Ratchathewi District, Bangkok, Thailand.

Samart Pakakasama (S)

Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Ratchathewi District, Bangkok, Thailand.

Ampaiwan Chuansumrit (A)

Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Ratchathewi District, Bangkok, Thailand.

Nattaphat Putawornsub (N)

Department of Biology, Mahidol Wittayanusorn School, Nakhon Pathom, Thailand.

Sawitt Sirasittikarn (S)

Department of Biology, Mahidol Wittayanusorn School, Nakhon Pathom, Thailand.

Sataporn Wantanawijarn (S)

Department of Biology, Mahidol Wittayanusorn School, Nakhon Pathom, Thailand.

Praguywan Kadegasem (P)

Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Ratchathewi District, Bangkok, Thailand.

Suradej Hongeng (S)

Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Ratchathewi District, Bangkok, Thailand.

Nongnuch Sirachainan (N)

Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Ratchathewi District, Bangkok, Thailand. nongnuch.sir@mahidol.ac.th.

Classifications MeSH