Borderline Case of TAFRO Syndrome and POEMS Syndrome.
Castleman disease
POEMS syndrome
TAFRO syndrome
lymphoproliferative disorder
Journal
Internal medicine (Tokyo, Japan)
ISSN: 1349-7235
Titre abrégé: Intern Med
Pays: Japan
ID NLM: 9204241
Informations de publication
Date de publication:
15 May 2021
15 May 2021
Historique:
pubmed:
18
12
2020
medline:
19
5
2021
entrez:
17
12
2020
Statut:
ppublish
Résumé
TAFRO syndrome and POEMS syndrome are lymphoproliferative disorders with elevated interleukin-6 and vascular endothelial growth factor (VEGF) levels; however, their underlying pathogenic mechanisms remain unclear. Similarities have been reported in the pathological findings of the lymph nodes of TAFRO syndrome, Multicentric Castleman disease (MCD), and some cases of POEMS syndrome. However, there is no consensus on the relationship among them. We encountered a case of lymphoproliferative disorder that presented with manifestations of both TAFRO syndrome and POEMS syndrome. This case may be a subtype of idiopathic MCD and will be very important for establishing the disease concept of TAFRO syndrome and POEMS syndrome.
Identifiants
pubmed: 33328401
doi: 10.2169/internalmedicine.5860-20
pmc: PMC8188039
doi:
Substances chimiques
Vascular Endothelial Growth Factor A
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1589-1595Références
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