Assessment of Peak Inspiratory Flow in Young Infants with Acute Viral Bronchiolitis: Physiological Basis for Initial Flow Setting in Patients Supported with High-Flow Nasal Cannula.
high-flow nasal cannula
respiratory distress
respiratory function
respiratory syncytial virus infections
Journal
The Journal of pediatrics
ISSN: 1097-6833
Titre abrégé: J Pediatr
Pays: United States
ID NLM: 0375410
Informations de publication
Date de publication:
04 2021
04 2021
Historique:
received:
03
08
2020
revised:
20
11
2020
accepted:
10
12
2020
pubmed:
18
12
2020
medline:
6
5
2021
entrez:
17
12
2020
Statut:
ppublish
Résumé
To assess the inspiratory demand in young infants with acute viral bronchiolitis to provide a physiological basis for initial flow setting for patients supported with high flow nasal cannula. Prospective study in 44 infants up to 6 months old with acute viral bronchiolitis, admitted to a pediatric intensive care unit from November 2017 to March 2019. Airflow measurements were performed using spirometry. The primary endpoint was the inspiratory demand as measured by peak tidal inspiratory flow (PTIF). The secondary endpoints were the relationships determined between PTIF, patient weight, and disease severity. Median (Q High flow nasal cannula therapy is used commonly to support infants with acute viral bronchiolitis. The efficiency of the device is optimal if the flow setting matches the patient's inspiratory demand. According to our results, a flow rate of <2.5 L/kg/minute would be appropriate in most situations.
Identifiants
pubmed: 33333115
pii: S0022-3476(20)31502-X
doi: 10.1016/j.jpeds.2020.12.020
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
239-245.e1Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.