Epidemiology of breast cancer in women based on diagnosis data from oncologists and senologists in Algeria.

Algeria Breast Neoplasms / epidemiology Female Humans Middle Aged Oncologists / standards Serology / standards

Breast cancer Diagnosis Incidence Mortality Treatment

Journal

Cancer treatment and research communications

ISSN: 2468-2942

Titre abrégé: Cancer Treat Res Commun

Pays: England

ID NLM: 101694651

Informations de publication

Date de publication:
2020

Historique:

received: 30 03 2020

revised: 12 08 2020

accepted: 28 09 2020

pubmed: 18 12 2020

medline: 18 11 2021

entrez: 17 12 2020

Statut: ppublish

Résumé

Breast cancer (BC) is a major health issue threatening women's life. No reliable epidemiological data on BC diagnosed by oncologists/senologists are available in Algeria. The BreCaReAl study, a non-interventional prospective cohort study, included adult women with confirmed BC in Algeria. Disease incidence, patients and disease characteristics, treatment patterns, and mortality rate were recorded up to 12 months of follow-up. Overall, 1,437 patients were analysed: median age was 48 [41;57] years and 337 (23.5%) women had a family history of BC. BC incidence was 22.3 (95% CI: 21.5; 23.2) cases per 100,000 inhabitants over 8 months. Delayed diagnosis was reported in 400 (29.2%) patients. First line of treatments were mainly chemotherapy and surgery. Twenty-eight serious adverse events were reported including 10 (37.0%) events which led to death. Mortality rate reached 3.2% at 12 months CONCLUSION: A delayed diagnosis highlights the importance of implementing more effective screening strategies.

Sections du résumé

BACKGROUND

Breast cancer (BC) is a major health issue threatening women's life. No reliable epidemiological data on BC diagnosed by oncologists/senologists are available in Algeria.

METHODS

The BreCaReAl study, a non-interventional prospective cohort study, included adult women with confirmed BC in Algeria. Disease incidence, patients and disease characteristics, treatment patterns, and mortality rate were recorded up to 12 months of follow-up.

RESULTS

Overall, 1,437 patients were analysed: median age was 48 [41;57] years and 337 (23.5%) women had a family history of BC. BC incidence was 22.3 (95% CI: 21.5; 23.2) cases per 100,000 inhabitants over 8 months. Delayed diagnosis was reported in 400 (29.2%) patients. First line of treatments were mainly chemotherapy and surgery. Twenty-eight serious adverse events were reported including 10 (37.0%) events which led to death. Mortality rate reached 3.2% at 12 months CONCLUSION: A delayed diagnosis highlights the importance of implementing more effective screening strategies.

Identifiants

DOI: 10.1016/j.ctarc.2020.100220 PMID: 33333411

pubmed: 33333411

pii: S2468-2942(20)30055-1

doi: 10.1016/j.ctarc.2020.100220

pii:

doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

Pagination

100220