Characterization of neonates born to mothers with SARS-CoV-2 infection: Review and meta-analysis.
COVID-19
SARS-CoV-2
infant
neonate
newborn
Journal
Pediatrics and neonatology
ISSN: 2212-1692
Titre abrégé: Pediatr Neonatol
Pays: Singapore
ID NLM: 101484755
Informations de publication
Date de publication:
01 2021
01 2021
Historique:
received:
28
07
2020
revised:
30
08
2020
accepted:
12
10
2020
pubmed:
19
12
2020
medline:
2
2
2021
entrez:
18
12
2020
Statut:
ppublish
Résumé
Characterization of neonates born to mothers with SARS-CoV-2 infection has been partially carried out. There has been no systematic review providing a holistic neonatal presentation including possible vertical transmission. A systematic literature search was performed using PubMed, Google Scholar and Web of Science up to June, 6 2020. Studies on neonates born to mothers with SARS-CoV-2 infection were included. A binary random effect model was used for prevalence and 95% confidence interval. 32 studies involving 261 neonates were included in meta-analysis. Most neonates born to infected mothers did not show any clinical abnormalities (80.4%). Clinical features were dyspnea in 11 (42.3%) and fever in 9 newborns (19.1%). Of 261 neonates, 120 neonates were tested for infection, of whom 12 (10.0%) tested positive. Swabs from placenta, cord blood and vaginal secretion were negative. Neonates are mostly non affected by the mother's SARS-CoV-2 infection. The risk of vertical transmission is low.
Identifiants
pubmed: 33334687
pii: S1875-9572(20)30164-9
doi: 10.1016/j.pedneo.2020.10.001
pmc: PMC7585378
pii:
doi:
Types de publication
Journal Article
Meta-Analysis
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
11-20Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
Copyright © 2020. Published by Elsevier B.V.
Déclaration de conflit d'intérêts
Declaration of competing interest All authors claim to have no conflicts of interest in connection with the subject of this publication.