Prevalence of epilepsy in Bangladesh: Results from a national household survey.

active epilepsy adults children epilepsy type perception treatment gap

Journal

Epilepsia open
ISSN: 2470-9239
Titre abrégé: Epilepsia Open
Pays: United States
ID NLM: 101692036

Informations de publication

Date de publication:
Dec 2020
Historique:
received: 22 05 2020
revised: 03 07 2020
accepted: 10 08 2020
entrez: 18 12 2020
pubmed: 19 12 2020
medline: 19 12 2020
Statut: epublish

Résumé

To determine the prevalence and types of epilepsy in Bangladesh. We conducted a nationwide population-based cross-sectional survey among Bangladeshi population of all ages, except children under one month. We surveyed 9839 participants (urban, 4918; rural, 4920) recruited at their households using multistage cluster sampling. Trained physicians with neurology background confirmed the diagnosis of suspected epilepsy cases identified by interviewer-administered questionnaires. We reported the overall and sex, residence, and age groups-specific prevalence of epilepsy per 1000 populations with 95% confidence interval. The national prevalence of epilepsy per 1000 was 8.4 (95% CI 5.6-11.1), urban 8.0 (4.6-11.4), and rural 8.5 (5.60-11.5). The prevalence in adult males and females was 9.2 (5.7-12.6) and 7.7 (3.6-11.7), respectively. The prevalence in children aged <18 years (8.2, 3.4-13.0 was similar to adults (8.5 (5.4-11.4). Among all epilepsy cases, 65.1% had active epilepsy. Their (active epilepsy) prevalence was 5.8 (3.5-8.1). Of them, 63.4% were not receiving treatment. Moreover, those who received allopathy treatment, 72.5% had low adherence leading to a high treatment gap. Our findings out of this first-ever national survey were similar to other Asian countries. However, the prevalence of active epilepsy and treatment gap were considerably higher. This study serves useful evidence for tailoring interventions aimed to reduce the burden of epilepsy-primarily through targeted community awareness program-and access to antiepileptic treatment in health facilities in Bangladesh.

Identifiants

pubmed: 33336124
doi: 10.1002/epi4.12430
pii: EPI412430
pmc: PMC7733657
doi:

Types de publication

Journal Article

Langues

eng

Pagination

526-536

Subventions

Organisme : World Health Organization
ID : 001
Pays : International

Informations de copyright

© 2020 The Authors. Epilepsia Open published by Wiley Periodicals LLC on behalf of International League Against Epilepsy.

Déclaration de conflit d'intérêts

None of the authors has any conflict of interest to disclose. The authors alone are responsible for their views expressed in this article, which do not necessarily represent the views, decisions, or policies of the institutions with which they are affiliated. We confirm that we have read the Journal's position on issues involved in ethical publication and affirm that this report is consistent with those guidelines.

Références

Epilepsia Open. 2020 Sep 18;5(4):526-536
pubmed: 33336124
Cochrane Database Syst Rev. 2011 Jan 19;(1):CD008312
pubmed: 21249705
Epilepsy Behav. 2012 Mar;23(3):291-3
pubmed: 22341966
Epilepsia. 1994 Sep-Oct;35(5):950-8
pubmed: 7925166
Can J Neurol Sci. 2004 May;31(2):257-60
pubmed: 15198454
Bull World Health Organ. 1993;71(2):247-58
pubmed: 8490989
J Med Assoc Thai. 2002 Oct;85(10):1066-73
pubmed: 12501897
Mymensingh Med J. 2018 Oct;27(4):776-784
pubmed: 30487494
Epilepsy Behav. 2012 Nov;25(3):297-302
pubmed: 23099230
Med Care. 1986 Jan;24(1):67-74
pubmed: 3945130
Paediatr Perinat Epidemiol. 1992 Apr;6(2):166-80
pubmed: 1584719
Bull World Health Organ. 2010 Apr;88(4):260-6
pubmed: 20431789
Epilepsia. 1993 Jul-Aug;34(4):592-6
pubmed: 8330566
Lancet Neurol. 2007 Jun;6(6):533-43
pubmed: 17509488
Epilepsy Behav. 2008 Nov;13(4):637-41
pubmed: 18656553
Epilepsia. 2002;43 Suppl 6:21-5
pubmed: 12190974
Epilepsy Res. 2012 Aug;101(1-2):129-34
pubmed: 22542198
Mymensingh Med J. 2014 Jan;23(1):56-61
pubmed: 24584374
Ann Indian Acad Neurol. 2014 Mar;17(Suppl 1):S3-S11
pubmed: 24791085
Epilepsy Res. 2015 Jul;113:68-75
pubmed: 25986192
Epilepsia. 2011 Aug;52(8):1382-7
pubmed: 21635234
Epilepsy Res. 2009 Dec;87(2-3):107-19
pubmed: 19782536
Epilepsia. 1981 Aug;22(4):489-501
pubmed: 6790275
Epilepsia. 2002;43 Suppl 6:9-11
pubmed: 12190968
Pediatrics. 2017 May;139(5):
pubmed: 28557750

Auteurs

Quazi Deen Mohammad (QD)

National Institute of Neurosciences and Hospital Dhaka Bangladesh.

Narayan Chandra Saha (NC)

Department of Pediatric Neurology National Institute of Neurosciences and Hospital Dhaka Bangladesh.

Md Badrul Alam (MB)

Department of Clinical Neurology National Institute of Neurosciences and Hospital Dhaka Bangladesh.

Seikh Azimul Hoque (SA)

Department of Paediatric Neurology National Institute of Neurosciences and Hospital Dhaka Bangladesh.

Ariful Islam (A)

Department of Paediatric Neurology National Institute of Neurosciences and Hospital Dhaka Bangladesh.

Rajib Nayan Chowdhury (RN)

Department of Neurophysiology National Institute of Neurosciences and Hospital Dhaka Bangladesh.

Mohammad Enayet Hussain (ME)

Department of Neurophysiology National Institute of Neurosciences and Hospital Dhaka Bangladesh.

Yamin Shahriar Chowdhury (YS)

Department of Paediatric Neurology National Institute of Neurosciences and Hospital Dhaka Bangladesh.

Sakhawat Hossain (S)

Neurology Sir Salimullah Medical College Dhaka Bangladesh.

Mahmood Ahmed Chowdhury (MA)

Autism & Child Development Center Chattogram Maa O Shishu Hospital Medical College Agrabad, Chattogram Bangladesh.

Matiur Rahman (M)

Sylhet MAG Osmani Medical College Sylhet Bangladesh.

Bikash Kumar Majumder (BK)

Pediatrics Rangpur Medical College Hospital Rangpur Bangladesh.

Abdus Salam (A)

Neurology Shaheed Sheikh Abu Naser Specialized Hospital Khulna Bangladesh.

Amitabh Sarker (A)

Neurology Sher-E-Bangla Medical College Barishal Bangladesh.

Md Kafil Uddin (MK)

Neurology Rajshahi Medical College Rajshahi Bangladesh.
National Institute of Neurosciences and Hospital Dhaka Bangladesh.

Mohammad Moniruzzaman (M)

Center for Epidemiologic Research in Asia Shiga University of Medical Science Otsu Japan.

Ferdous Hakim (F)

Mental and Neurology Study Team National Institute of Neurosciences and Hospital Dhaka Bangladesh.

Rijwan Bhuiyan (R)

Mental and Neurology Study Team National Institute of Neurosciences and Hospital Dhaka Bangladesh.

Nazneen Anwar (N)

World Health Organization Regional Office for South- East Asia New Delhi India.

Mohammad Mostafa Zaman (MM)

World Health Organization Bangladesh Dhaka Bangladesh.

Classifications MeSH