Interdialytic weight gain of less than 2.5% seems to limit cardiac damage during hemodialysis.
Biocompatibility
NT-pro-BNP
emboli
heart
hemodialysis
interdialytic weight gain
pentraxin
troponin
Journal
The International journal of artificial organs
ISSN: 1724-6040
Titre abrégé: Int J Artif Organs
Pays: United States
ID NLM: 7802649
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
pubmed:
20
12
2020
medline:
19
8
2021
entrez:
19
12
2020
Statut:
ppublish
Résumé
To investigate if a single low-flux HD induces a rise in cardiac biomarkers and if a change in clinical approach may limit such mechanism. A total of 20 chronic HD patients each underwent three different study-dialyses. Dialyzers (low-flux polysulfone, 1.8 sqm) had been stored either dry or wet (Wet) and the blood level in the venous chamber kept low or high. Laboratory results were measured at baseline, 30 and 180 min, adjusted for the effect of fluid shift. Ultrasound measured microemboli signals (MES) within the return line. Hemodialysis raised cardiac biomarkers ( Hemodialysis, independent of type of dialyzer storage, was associated with raised cardiac biomarkers, more profoundly in patients with higher pre-dialysis values and IDWG. A limitation in IDWG to <2.5% and prolonged ultrafiltration time may limit cardiac strain during HD, especially in patients with cardiovascular risk.
Identifiants
pubmed: 33339470
doi: 10.1177/0391398820981385
pmc: PMC8366174
doi:
Substances chimiques
Biomarkers
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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