In situ melanoma of oral cavity: Diagnosis and treatment of a rare entity.
Cancer
Early diagnosis
Head and neck tumor
Melanoma
Oral cavity
Oral health
Oral melanoma
Journal
Oral oncology
ISSN: 1879-0593
Titre abrégé: Oral Oncol
Pays: England
ID NLM: 9709118
Informations de publication
Date de publication:
04 2021
04 2021
Historique:
received:
18
11
2020
accepted:
22
11
2020
pubmed:
21
12
2020
medline:
18
11
2021
entrez:
20
12
2020
Statut:
ppublish
Résumé
Oral melanoma is an extremely aggressive and rare tumor. Commonly, oral melanomas are diagnosed as invasive tumors, which considerably reduces the chances of cure. In situ oral melanomas being exceedingly rare, which makes its clinicopathological and prognostic characteristics poorly known. Herein, we report a case of 67-year-old non-white woman with a large black patch on the maxillary alveolar mucosa. A biopsy was made and microscopical analysis revealed moderate atypical junctional melanocytic. Tumor cells were positive for S100 (Polyclonal), Melan-A (Clone A103) and Melanosome (HMB-45). The diagnosis of in situ oral melanoma was made and the patient was treated surgically with partial maxillectomy and rehabilitated with obturator prosthesis. Although extremely rare in situ melanomas should be considered in the differential diagnosis of non-invasive pigmented lesions of the oral mucosa.
Identifiants
pubmed: 33341377
pii: S1368-8375(20)30552-2
doi: 10.1016/j.oraloncology.2020.105116
pii:
doi:
Types de publication
Case Reports
Letter
Langues
eng
Sous-ensembles de citation
IM
Pagination
105116Informations de copyright
Copyright © 2020 Elsevier Ltd. All rights reserved.