The coagulation profile as a marker for acute appendicitis in the paediatric population: Retrospective study.
Appendicitis
children
coagulation
Journal
African journal of paediatric surgery : AJPS
ISSN: 0974-5998
Titre abrégé: Afr J Paediatr Surg
Pays: India
ID NLM: 101255062
Informations de publication
Date de publication:
Historique:
entrez:
21
12
2020
pubmed:
22
12
2020
medline:
11
5
2021
Statut:
ppublish
Résumé
Appendicitis is the commonest and most frequently misdiagnosed acute abdominal surgical illness in the paediatric population worldwide. The aim of this study is to evaluate the role of coagulation profile in acute appendicitis (AA) in children. we retrospectively collected data of patients submitted to appendectomy from 2011 to 2017. According to histopathology, patients were divided into three groups: not histologically confirmed AA (NAA), simple AA (SAA) and complicated AA (CAA). White blood cell (WBC) count, relative neutrophilia (Neutr%), C-reactive protein (CRP), prothrombin time ratio (PTratio), activated partial thromboplastin time ratio (APTTratio) and fibrinogen (Fib) were compared among groups. Three hundred and seven patients were included: 57 NAA, 184 SAA and 66 CAA. WBC was significantly different among groups: CAA (mean 16.67 × 10 extrinsic coagulation pathway is altered in AA, especially in CAA. Coagulation can be useful in the diagnostic and perioperative anaesthetic management of AA in children. Fib seems to have the highest accuracy.
Identifiants
pubmed: 33342835
pii: AfrJPaediatrSurg_2020_17_3_59_303989
doi: 10.4103/ajps.AJPS_52_20
pmc: PMC8051619
doi:
Substances chimiques
Biomarkers
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
59-63Déclaration de conflit d'intérêts
None
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