Relationship between

BRCA1 MUTYH OGG1 base excision repair breast cancer gene expression mutation ovarian cancer oxidative stress prevention

Journal

Molecular and clinical oncology
ISSN: 2049-9450
Titre abrégé: Mol Clin Oncol
Pays: England
ID NLM: 101613422

Informations de publication

Date de publication:
Jan 2021
Historique:
received: 14 02 2020
accepted: 29 09 2020
entrez: 21 12 2020
pubmed: 22 12 2020
medline: 22 12 2020
Statut: ppublish

Résumé

The aetiology of breast and ovarian cancer (BC/OC) is multi-factorial. At present, the involvement of base excision repair (BER) glycosylases (MUTYH and OGG1) in BC/OC predisposition is controversial. The present study investigated whether germline mutation status and mRNA expression of two BER genes,

Identifiants

pubmed: 33343895
doi: 10.3892/mco.2020.2177
pii: MCO-0-0-02177
pmc: PMC7725208
doi:

Types de publication

Journal Article

Langues

eng

Pagination

15

Informations de copyright

Copyright: © Moscatello et al.

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Auteurs

Carmelo Moscatello (C)

Department of Medical, Oral and Biotechnological Sciences, 'G. d'Annunzio' University of Chieti-Pescara, I-66100 Chieti, Italy.

Marta Di Nicola (M)

Department of Medical, Oral and Biotechnological Sciences, 'G. d'Annunzio' University of Chieti-Pescara, I-66100 Chieti, Italy.

Serena Veschi (S)

Department of Pharmacy, 'G. d'Annunzio' University of Chieti-Pescara, I-66100 Chieti, Italy.

Patrizia Di Gregorio (P)

Department of Psychological, Health and Territorial Sciences, School of Medicine and Health Sciences, 'G. d'Annunzio' University of Chieti-Pescara, I-66100 Chieti, Italy.

Ettore Cianchetti (E)

Department of Medical, Oral and Biotechnological Sciences, 'G. d'Annunzio' University of Chieti-Pescara, I-66100 Chieti, Italy.

Liborio Stuppia (L)

Immunohaematology and Transfusional Medicine Service, 'SS. Annunziata' Hospital, I-66100 Chieti, Italy.

Pasquale Battista (P)

Department of Medical, Oral and Biotechnological Sciences, 'G. d'Annunzio' University of Chieti-Pescara, I-66100 Chieti, Italy.

Alessandro Cama (A)

Department of Pharmacy, 'G. d'Annunzio' University of Chieti-Pescara, I-66100 Chieti, Italy.

Maria Cristina Curia (MC)

Department of Medical, Oral and Biotechnological Sciences, 'G. d'Annunzio' University of Chieti-Pescara, I-66100 Chieti, Italy.

Gitana Maria Aceto (GM)

Department of Medical, Oral and Biotechnological Sciences, 'G. d'Annunzio' University of Chieti-Pescara, I-66100 Chieti, Italy.

Classifications MeSH