No impact of cancer and plague-relevant
Immunogenetics
pathogen-associated molecular patterns
sars-CoV-2
Journal
Oncoimmunology
ISSN: 2162-402X
Titre abrégé: Oncoimmunology
Pays: United States
ID NLM: 101570526
Informations de publication
Date de publication:
08 12 2020
08 12 2020
Historique:
entrez:
21
12
2020
pubmed:
22
12
2020
medline:
8
1
2021
Statut:
epublish
Résumé
Formyl peptide receptor 1 (FPR1) is a pattern-recognition receptor that detects bacterial as well as endogenous danger-associated molecular patterns to trigger innate immune responses by myeloid cells. A single nucleotide polymorphism, rs867228 (allelic frequency 19-20%), in the gene coding for FPR1 accelerates the manifestation of multiple carcinomas, likely due to reduced anticancer immunosurveillance secondary to a defect in antigen presentation by dendritic cells. Another polymorphism in
Identifiants
pubmed: 33344044
doi: 10.1080/2162402X.2020.1857112
pii: 1857112
pmc: PMC7734042
doi:
Substances chimiques
FPR1 protein, human
0
Receptors, Formyl Peptide
0
Types de publication
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1857112Informations de copyright
© 2020 The Author(s). Published with license by Taylor & Francis Group, LLC.
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