Elastosis Perforans Serpiginosa: a D-penicillamine induced dermatoses in a patient with Wilson's disease.
Biopsy
Elastic tissue
Skin Diseases
Journal
Autopsy & case reports
ISSN: 2236-1960
Titre abrégé: Autops Case Rep
Pays: Brazil
ID NLM: 101640070
Informations de publication
Date de publication:
06 May 2020
06 May 2020
Historique:
entrez:
21
12
2020
pubmed:
22
12
2020
medline:
22
12
2020
Statut:
epublish
Résumé
Long term use of D-penicillamine for Wilson's disease can be associated with many adverse reactions and systemic side effects. We report the case of a 28-year-old male patient diagnosed with Wilson's disease presenting with a serpiginous raised violaceous skin lesion in the anterior aspect of the neck over the last six months and two small papules with central umbilication during the last month. Histopathological examination of skin lesions demonstrated transepidermal perforating channel, and the Verhoeff's-van Gieson stain showed marked increase number of irregular serrated elastic fibers suggesting the diagnosis of D- penicillamine induced elastosis perforans serpiginosa.
Identifiants
pubmed: 33344284
doi: 10.4322/acr.2020.167
pii: autopsy051119
pmc: PMC7703465
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e2020167Informations de copyright
Autopsy and Case Reports. ISSN 2236-1960. Copyright © 2020.
Déclaration de conflit d'intérêts
Conflict of interest: None
Références
Am J Dermatopathol. 1986 Aug;8(4):314-20
pubmed: 3766920
J Dermatol. 1997 Jul;24(7):458-65
pubmed: 9267106
Int J Dermatol. 1985 Jun;24(5):267-79
pubmed: 3160676
J Am Acad Dermatol. 2009 Apr;60(4):700-3
pubmed: 19293020
Clin Exp Dermatol. 2016 Aug;41(6):667-70
pubmed: 27378586
J Am Acad Dermatol. 1981 Mar;4(3):300-15
pubmed: 6452467
J Assoc Physicians India. 1998 Jul;46(7):602-5
pubmed: 12152840
Lancet Gastroenterol Hepatol. 2017 Feb;2(2):144
pubmed: 28403984
Arch Dermatol. 1968 Apr;97(4):381-93
pubmed: 4230639
Clin Exp Dermatol. 2001 Sep;26(6):521-4
pubmed: 11678881
J Invest Dermatol. 1960 Aug;35:113-22
pubmed: 13844513