Gestational gigantomastia with fatal outcome.

Breast Diseases Gigantomastia HIV Pregnancy Pregnancy Complications

Journal

Autopsy & case reports
ISSN: 2236-1960
Titre abrégé: Autops Case Rep
Pays: Brazil
ID NLM: 101640070

Informations de publication

Date de publication:
20 Nov 2020
Historique:
entrez: 21 12 2020
pubmed: 22 12 2020
medline: 22 12 2020
Statut: epublish

Résumé

Gigantomastia is a rare disease defined by an extreme and rapid enlargement of the breast, generally bilateral. The majority of cases are reported in pregnant women. Ninety-eight cases of gestational gigantomastia have been identified in electronic databases, and those with fatal outcomes comprised only 2 cases (2%). Despite its benign nature, it can lead to severe complications and even death. Its etiology has not been fully elucidated, but it has been speculated that a hormonal component may play a role in the pathogenesis. Currently, treatment options are limited, and surgery is gaining importance, but it is often not feasible in low-resource settings. Herein, we describe a case of a 30-year-old HIV-positive female with no relevant past medical history, who died due to the complications of gestational gigantomastia at the Maputo Central Hospital, in Mozambique.

Identifiants

pubmed: 33344327
doi: 10.4322/acr.2020.213
pii: autopsy-10-04-e2020213
pmc: PMC7703335
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e2020213

Informations de copyright

Copyright: © 2020 The Authors.

Déclaration de conflit d'intérêts

Conflict of interest: none.

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Auteurs

Natalia Rakislova (N)

Barcelona Institute for Global health (ISGlobal), Hospital Clínic- Universitat de Barcelona, Barcelona, Spain.
Universitat de Barcelona, Hospital Clinic, Department of Pathology, Barcelona, Spain.

Lucilia Lovane (L)

Maputo Central Hospital, Department of Pathology, Maputo, Mozambique.

Fabiola Fernandes (F)

Maputo Central Hospital, Department of Pathology, Maputo, Mozambique.
Eduardo Mondlane University, Faculty of Medicine, Department of Pathology, Maputo, Mozambique.

Emília Gonçalves (E)

Eduardo Mondlane University, Faculty of Medicine, Department of Ginecology and Obstetrics, Maputo, Mozambique.
Maputo Central Hospital, Department of Ginecology and Obstetrics, Maputo, Mozambique.

Quique Bassat (Q)

Barcelona Institute for Global health (ISGlobal), Hospital Clínic- Universitat de Barcelona, Barcelona, Spain.
Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain.
University of Barcelona, Hospital Sant Joan de Déu, Pediatrics Department, Pediatric Infectious Diseases Unit, Barcelona, Spain.
Consorcio de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.

Sibone Mocumbi (S)

Eduardo Mondlane University, Faculty of Medicine, Department of Ginecology and Obstetrics, Maputo, Mozambique.
Maputo Central Hospital, Department of Ginecology and Obstetrics, Maputo, Mozambique.

Jaume Ordi (J)

Barcelona Institute for Global health (ISGlobal), Hospital Clínic- Universitat de Barcelona, Barcelona, Spain.
Universitat de Barcelona, Hospital Clinic, Department of Pathology, Barcelona, Spain.

Carla Carrilho (C)

Maputo Central Hospital, Department of Pathology, Maputo, Mozambique.
Eduardo Mondlane University, Faculty of Medicine, Department of Pathology, Maputo, Mozambique.

Classifications MeSH