Current approaches and future prospects of nanofibers: a special focus on antimicrobial drug delivery.


Journal

Journal of drug targeting
ISSN: 1029-2330
Titre abrégé: J Drug Target
Pays: England
ID NLM: 9312476

Informations de publication

Date de publication:
07 2021
Historique:
pubmed: 22 12 2020
medline: 24 12 2021
entrez: 21 12 2020
Statut: ppublish

Résumé

Antibacterial nanofibers have a great potential for effective treatment of infections. They act as drug reservoir systems that release higher quantities of antibacterial agents/drug in a controlled manner at infection sites and prevent drug resistance, while concomitantly decreasing the systemic toxicity. With this drug delivery system, it is also possible to achieve multiple drug entrapment and also simultaneous or sequential release kinetics at the site of action. Therefore, advances in antibacterial nanofibers as drug delivery systems were overviewed within this article. Recently published data on antibacterial drug delivery was also summarised to provide a view of the current state of art in this field. Although antibacterial use seems to be limited and one can ask that '

Identifiants

pubmed: 33345641
doi: 10.1080/1061186X.2020.1867991
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

563-575

Auteurs

Betul Topcu (B)

Department of Pharmaceutical Technology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.

Merve Gultekinoglu (M)

Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.

Selin Seda Timur (SS)

Department of Pharmaceutical Technology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.

Ipek Eroglu (I)

Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.

Kezban Ulubayram (K)

Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.
Department of Nanotechnology and Nanomedicine, Institute of Graduate Studies in Science and Engineering, Ankara, Turkey.
Department of Bioengineering, Institute of Graduate Studies in Science and Engineering, Hacettepe University, Ankara, Turkey.

Hakan Eroglu (H)

Department of Pharmaceutical Technology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.

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Classifications MeSH