Mobile digital x-ray and portable cartridge based nucleic acid amplification test machines for point-of-care diagnosis of TB in rural India.
CBNAAT Edge
GeneXpert
active case finding
digital chest x-ray
point-of-care test
Journal
Transactions of the Royal Society of Tropical Medicine and Hygiene
ISSN: 1878-3503
Titre abrégé: Trans R Soc Trop Med Hyg
Pays: England
ID NLM: 7506129
Informations de publication
Date de publication:
02 08 2021
02 08 2021
Historique:
received:
26
07
2020
revised:
25
10
2020
accepted:
19
11
2020
pubmed:
22
12
2020
medline:
6
8
2021
entrez:
21
12
2020
Statut:
ppublish
Résumé
There is no experience of point-of-care (POC) microbiological confirmation for TB in India in field settings. Under the TB-Free Haryana project, a mobile van-mounted digital x-ray and portable GeneXpert system screened all presumptive TB patients with strong clinic-radiological suspicion for TB. Of 1673 x-rays, 215 (13%) had findings suggestive of TB, 109 had strong clinical suspicion and were eligible for POC GeneXpert, in whom a test was performed in 82 (75%) cases; 59 (72%) tested positive and were initiated on treatment within 24 h. A mobile van equipped with digital x-ray and POC GeneXpert is feasible and has a good success rate with potential for replication.
Sections du résumé
BACKGROUND
There is no experience of point-of-care (POC) microbiological confirmation for TB in India in field settings.
METHODS
Under the TB-Free Haryana project, a mobile van-mounted digital x-ray and portable GeneXpert system screened all presumptive TB patients with strong clinic-radiological suspicion for TB.
RESULTS
Of 1673 x-rays, 215 (13%) had findings suggestive of TB, 109 had strong clinical suspicion and were eligible for POC GeneXpert, in whom a test was performed in 82 (75%) cases; 59 (72%) tested positive and were initiated on treatment within 24 h.
CONCLUSIONS
A mobile van equipped with digital x-ray and POC GeneXpert is feasible and has a good success rate with potential for replication.
Identifiants
pubmed: 33347591
pii: 6043210
doi: 10.1093/trstmh/traa152
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
937-939Subventions
Organisme : Medanta Hospital's Corporate Social Responsibility Fund
Informations de copyright
© The Author(s) 2020. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene.