Genistein enhances the effects of L-asparaginase on inducing cell apoptosis in human leukemia cancer HL-60 cells.
Genistein
L-asparaginase
apoptosis
human leukemia cancer HL-60 cells
mitochondria dysfunction
Journal
Environmental toxicology
ISSN: 1522-7278
Titre abrégé: Environ Toxicol
Pays: United States
ID NLM: 100885357
Informations de publication
Date de publication:
May 2021
May 2021
Historique:
received:
07
04
2020
accepted:
29
11
2020
pubmed:
22
12
2020
medline:
28
4
2021
entrez:
21
12
2020
Statut:
ppublish
Résumé
Genistein (GEN) has been shown to induce apoptotic cell death in various human cancer cells. L-asparaginase (Asp), a clinical drug for leukemia, has been shown to induce cell apoptosis in leukemia cells. No available information concerning GEN combined with Asp increased the cell apoptosis compared to GEN or Asp treatment alone. The objective of this study is to evaluate the anti-leukemia activity of GEN combined with Asp on human leukemia HL-60 cells in vitro. The cell viability, the distribution of cell cycle, apoptotic cell death, and the level of ΔΨ
Substances chimiques
Genistein
DH2M523P0H
Asparaginase
EC 3.5.1.1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
764-772Informations de copyright
© 2020 Wiley Periodicals LLC.
Références
Ferlay J, Parkin DM, Steliarova-Foucher E. Estimates of cancer incidence and mortality in Europe in 2008. Eur J Cancer. 2010;46:765-781.
Siegel RL, Miller KD, Jemal A. Cancer statistics, 2018. CA Cancer J Clin. 2018;68:7-30.
Lee SJ, Kim KH, Park JS, et al. Comparative analysis of cell surface proteins in chronic and acute leukemia cell lines. Biochem Biophys Res Commun. 2007;357:620-626.
Yeh MY, Shih YL, Chung HY, et al. Chitosan promotes immune responses, ameliorating total mature white blood cell numbers, but increases glutamic oxaloacetic transaminase and glutamic pyruvic transaminase, and ameliorates lactate dehydrogenase levels in leukemia mice in vivo. Mol Med Rep. 2017;16:2483-2490.
Hunger SP, Mullighan CG. Acute lymphoblastic leukemia in children. N Engl J Med. 2015;373:1541-1552.
Glade MJ. Food, nutrition, and the prevention of cancer: a global perspective. American Institute for Cancer Research/World Cancer Research Fund, American Institute for Cancer Research, 1997. Nutrition. 1999;15:523-526.
van't Veer P, Jansen MC, Klerk M, Kok FJ. Fruits and vegetables in the prevention of cancer and cardiovascular disease. Public Health Nutr. 2000;3:103-107.
Snyder RD, Gillies PJ. Reduction of genistein clastogenicity in Chinese hamster V79 cells by daidzein and other flavonoids. Food Chem Toxicol. 2003;41:1291-1298.
Banerjee S, Zhang Y, Ali S, et al. Molecular evidence for increased antitumor activity of gemcitabine by genistein in vitro and in vivo using an orthotopic model of pancreatic cancer. Cancer Res. 2005;65:9064-9072.
Banerjee S, Zhang Y, Wang Z, et al. In vitro and in vivo molecular evidence of genistein action in augmenting the efficacy of cisplatin in pancreatic cancer. Int J Cancer. 2007;120:906-917.
Hwang KA, Kang NH, Yi BR, Lee HR, Park MA, Choi KC. Genistein, a soy phytoestrogen, prevents the growth of BG-1 ovarian cancer cells induced by 17beta-estradiol or bisphenol a via the inhibition of cell cycle progression. Int J Oncol. 2013;42:733-740.
Hwang KA, Park MA, Kang NH, et al. Anticancer effect of genistein on BG-1 ovarian cancer growth induced by 17 beta-estradiol or bisphenol a via the suppression of the crosstalk between estrogen receptor alpha and insulin-like growth factor-1 receptor signaling pathways. Toxicol Appl Pharmacol. 2013;272:637-646.
Ouyang G, Yao L, Ruan K, Song G, Mao Y, Bao S. Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways. Cell Biol Int. 2009;33:1237-1244.
Yamasaki M, Mine Y, Nishimura M, et al. Genistein induces apoptotic cell death associated with inhibition of the NF-kappaB pathway in adult T-cell leukemia cells. Cell Biol Int. 2013;37:742-747.
Sanchez Y, Amran D, de Blas E, Aller P. Regulation of genistein-induced differentiation in human acute myeloid leukaemia cells (HL60, NB4) protein kinase modulation and reactive oxygen species generation. Biochem Pharmacol. 2009;77:384-396.
Piatkowska-Jakubas B, Krawczyk-Kulis M, Giebel S, et al. Use of L-asparaginase in acute lymphoblastic leukemia: recommendations of the polish adult leukemia group. Pol Arch Med Wewn. 2008;118:664-669.
Willems L, Jacque N, Jacquel A, et al. Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia. Blood. 2013;122:3521-3532.
Sugimoto K, Suzuki HI, Fujimura T, et al. A clinically attainable dose of L-asparaginase targets glutamine addiction in lymphoid cell lines. Cancer Sci. 2015;106:1534-1543.
He Y, Li B, Zhang H, et al. L-asparaginase induces in AML U937 cells apoptosis via an AIF-mediated mechanism. Front Biosci (Landmark Ed). 2014;19:515-527.
Song P, Ye L, Fan J, et al. Asparaginase induces apoptosis and cytoprotective autophagy in chronic myeloid leukemia cells. Oncotarget. 2015;6:3861-3873.
Huang YC, Kuo CL, Lu KW, et al. 18alpha-Glycyrrhetinic acid induces apoptosis of HL-60 human leukemia cells through Caspases- and mitochondria-dependent signaling pathways. Molecules. 2016;21:872.
Ruiz-Medina BE, Lerma D, Hwang M, et al. Green barley mitigates cytotoxicity in human lymphocytes undergoing aggressive oxidative stress, via activation of both the Lyn/PI3K/Akt and MAPK/ERK pathways. Sci Rep. 2019;9:6005.
Shang HS, Shih YL, Lee CH, et al. Sulforaphane-induced apoptosis in human leukemia HL-60 cells through extrinsic and intrinsic signal pathways and altering associated genes expression assayed by cDNA microarray. Environ Toxicol. 2017;32:311-328.
Robles-Escajeda E, Lerma D, Nyakeriga AM, et al. Searching in mother nature for anti-cancer activity: anti-proliferative and pro-apoptotic effect elicited by green barley on leukemia/lymphoma cells. PLoS One. 2013;8:e73508.
Hsu YC, Chiang JH, Yu CS, et al. Antitumor effects of deguelin on H460 human lung cancer cells in vitro and in vivo: roles of apoptotic cell death and H460 tumor xenografts model. Environ Toxicol. 2017;32:84-98.
Leung YM, Wong KL, Chen SW, et al. Down-regulation of voltage-gated Ca2+ channels in Ca2+ store-depleted rat insulinoma RINm5F cells. Biomedicine. 2013;3:130-139.
Lee MR, Lin C, Lu CC, et al. YC-1 induces G0/G1 phase arrest and mitochondria-dependent apoptosis in cisplatin-resistant human oral cancer CAR cells. Biomedicine. 2017;7:12.
Chang Y-M, Velmurugan BK, Kuo W-W, et al. Inhibitory effect of alpinate Oxyphyllae fructus extracts on Ang II-induced cardiac pathological remodeling-related pathways in H9c2 cardiomyoblast cells. Biomedicine. 2013;3:148-152.
Collins SJ, Gallo RC, Gallagher RE. Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture. Nature. 1977;270:347-349.
Fontana JA, Colbert DA, Deisseroth AB. Identification of a population of bipotent stem cells in the HL60 human promyelocytic leukemia cell line. Proc Natl Acad Sci U S A. 1981;78:3863-3866.
Safarzadeh E, Sandoghchian Shotorbani S, Baradaran B. Herbal medicine as inducers of apoptosis in cancer treatment. Adv Pharm Bull. 2014;4:421-427.
Collins RJ, Verschuer LA, Harmon BV, Prentice RL, Pope JH, Kerr JF. Spontaneous programmed death (apoptosis) of B-chronic lymphocytic leukaemia cells following their culture in vitro. Br J Haematol. 1989;71:343-350.
Chen H, Wang H, An J, Shang Q, Ma J. Plumbagin induces RPE cell cycle arrest and apoptosis via p38 MARK and PI3K/AKT/mTOR signaling pathways in PVR. BMC Complement Altern Med. 2018;18:89.
Xu Z, Shao J, Li L, et al. All-trans retinoic acid synergizes with topotecan to suppress AML cells via promoting RARalpha-mediated DNA damage. BMC Cancer. 2016;16:2.
Negretto GW, Deon M, Burin M, et al. In vitro effect of genistein on DNA damage in leukocytes from mucopolysaccharidosis IVA patients. Mol Genet Metab. 2014;111:205-208.
Chueh FS, Chen YL, Hsu SC, et al. Triptolide induced DNA damage in A375.S2 human malignant melanoma cells is mediated via reduction of DNA repair genes. Oncol Rep. 2013;29:613-618.
Shimizu T, Kubota M, Adachi S, et al. Pre-treatment of a human T-lymphoblastoid cell line with L-asparaginase reduces etoposide-induced DNA strand breakage and cytotoxicity. Int J Cancer. 1992;50:644-648.
Chou HY, Chueh FS, Ma YS, et al. Bufalin induced apoptosis in SCC4 human tongue cancer cells by decreasing Bcl2 and increasing Bax expression via the mitochondriadependent pathway. Mol Med Rep. 2017;16:7959-7966.
Yang JS, Hour MJ, Huang WW, Lin KL, Kuo SC, Chung JG. MJ-29 inhibits tubulin polymerization, induces mitotic arrest, and triggers apoptosis via cyclin-dependent kinase 1-mediated Bcl-2 phosphorylation in human leukemia U937 cells. J Pharmacol Exp Ther. 2010;334:477-488.