Enhancement in serum (1-3)-β-D-glucan level by cutaneous alternariosis: A case report and literature review.
(1–3)-β-D-glucan detection
Alternaria
Cutaneous infection
Phaeohyphomycosis
Journal
Microbial pathogenesis
ISSN: 1096-1208
Titre abrégé: Microb Pathog
Pays: England
ID NLM: 8606191
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
received:
02
07
2020
revised:
24
11
2020
accepted:
06
12
2020
pubmed:
22
12
2020
medline:
22
6
2021
entrez:
21
12
2020
Statut:
ppublish
Résumé
Contamination with the fungus Alternaria spp. is often considered to have originated from laboratory sources, which occasionally causes infection in immunocompromised patients, termed as phaeohyphomycosis. Here, we have reported a case of cutaneous alternariosis caused by Alternaria alternata. This diagnosis was based on microscopic examination and mycological culturing of patient's vesicular lesions, with the use of 5 molecular markers (namely, ITS, ATPase, Actin, rpb2, and tef1) for strain identification. We noted that Alternaria infection caused an increase in the serum level of (1-3)-β-D-glucan (BG) in the patients. To the best of our knowledge, no such finding has been reported in previously in the literature.
Identifiants
pubmed: 33347963
pii: S0882-4010(20)31069-X
doi: 10.1016/j.micpath.2020.104703
pii:
doi:
Substances chimiques
Antifungal Agents
0
beta-Glucans
0
Types de publication
Case Reports
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
104703Informations de copyright
Copyright © 2020 Elsevier Ltd. All rights reserved.