Homeopathy in Experimental Cancer Models: A Systematic Review.


Journal

Homeopathy : the journal of the Faculty of Homeopathy
ISSN: 1476-4245
Titre abrégé: Homeopathy
Pays: Germany
ID NLM: 101140517

Informations de publication

Date de publication:
May 2021
Historique:
pubmed: 22 12 2020
medline: 13 10 2021
entrez: 21 12 2020
Statut: ppublish

Résumé

 Complementary and alternative medicine, including homeopathy, is widely used to improve well-being among cancer patients and reduce adverse effects of conventional treatment. In contrast, there are few studies on the use of homeopathic medicines to treat the disease itself. Yet, evidence of possible effectiveness of homeopathic high dilutions in experimental cancer models has been published during the past 20 years.  The aim of the study was to perform a systematic review of fundamental research studies on homeopathic high dilutions in cancer.  Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline, we conducted a literature search in the database PubMed for original publications, from 2000 to 2018 and in English, on  Twenty-three articles met the inclusion criteria-14  Fundamental research of homeopathy in cancer is still at an early stage and has mainly been performed by a few groups of investigators. The results point to an interference of well-selected homeopathic medicines with cell cycle and apoptotic mechanisms in cancer cells. However, these findings still need independent reproduction.

Sections du résumé

BACKGROUND BACKGROUND
 Complementary and alternative medicine, including homeopathy, is widely used to improve well-being among cancer patients and reduce adverse effects of conventional treatment. In contrast, there are few studies on the use of homeopathic medicines to treat the disease itself. Yet, evidence of possible effectiveness of homeopathic high dilutions in experimental cancer models has been published during the past 20 years.
AIM OBJECTIVE
 The aim of the study was to perform a systematic review of fundamental research studies on homeopathic high dilutions in cancer.
METHODS METHODS
 Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline, we conducted a literature search in the database PubMed for original publications, from 2000 to 2018 and in English, on
RESULTS RESULTS
 Twenty-three articles met the inclusion criteria-14
CONCLUSION CONCLUSIONS
 Fundamental research of homeopathy in cancer is still at an early stage and has mainly been performed by a few groups of investigators. The results point to an interference of well-selected homeopathic medicines with cell cycle and apoptotic mechanisms in cancer cells. However, these findings still need independent reproduction.

Identifiants

pubmed: 33348419
doi: 10.1055/s-0040-1716369
doi:

Substances chimiques

Antineoplastic Agents 0
Materia Medica 0

Types de publication

Journal Article Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

76-85

Informations de copyright

Faculty of Homeopathy. This article is published by Thieme.

Déclaration de conflit d'intérêts

None declared.

Auteurs

Andreza Pereira Dos Santos (AP)

Research Center, Universidade Paulista, UNIP, Graduate Program in Environmental and Experimental Pathology, São Paulo, Brazil.

Thayná Neves Cardoso (TN)

Research Center, Universidade Paulista, UNIP, Graduate Program in Environmental and Experimental Pathology, São Paulo, Brazil.

Silvia Waisse (S)

Pontifical Catholic University of São Paulo, PUC-SP, Graduate Program in History of Science, São Paulo, Brazil.

Leoni Villano Bonamin (LV)

Research Center, Universidade Paulista, UNIP, Graduate Program in Environmental and Experimental Pathology, São Paulo, Brazil.

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Classifications MeSH